IL121053A - Method for removing N-terminal methionine - Google Patents

Method for removing N-terminal methionine

Info

Publication number
IL121053A
IL121053A IL12105397A IL12105397A IL121053A IL 121053 A IL121053 A IL 121053A IL 12105397 A IL12105397 A IL 12105397A IL 12105397 A IL12105397 A IL 12105397A IL 121053 A IL121053 A IL 121053A
Authority
IL
Israel
Prior art keywords
terminal
methionine residue
terminal methionine
peptide
salt
Prior art date
Application number
IL12105397A
Other languages
English (en)
Other versions
IL121053A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL121053A0 publication Critical patent/IL121053A0/xx
Publication of IL121053A publication Critical patent/IL121053A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Forging (AREA)
IL12105397A 1996-06-14 1997-06-10 Method for removing N-terminal methionine IL121053A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15463496 1996-06-14

Publications (2)

Publication Number Publication Date
IL121053A0 IL121053A0 (en) 1997-11-20
IL121053A true IL121053A (en) 2000-12-06

Family

ID=15588495

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12105397A IL121053A (en) 1996-06-14 1997-06-10 Method for removing N-terminal methionine

Country Status (11)

Country Link
US (2) US6066470A (el)
EP (1) EP0812856B1 (el)
KR (1) KR100478747B1 (el)
CN (1) CN1158303C (el)
AT (1) ATE185146T1 (el)
CA (1) CA2207723C (el)
DE (1) DE69700561T2 (el)
DK (1) DK0812856T3 (el)
ES (1) ES2136458T3 (el)
GR (1) GR3032139T3 (el)
IL (1) IL121053A (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768743B1 (fr) * 1997-09-23 2001-09-14 Bio Merieux Procede de lyse de micro-organisme
CN1322211A (zh) * 1998-10-05 2001-11-14 武田药品工业株式会社 除去n－末端蛋氨酸的方法
AU1797100A (en) * 1998-12-11 2000-07-03 Takeda Chemical Industries Ltd. Process for producing apelin
WO2002046405A1 (fr) * 2000-12-07 2002-06-13 Takeda Chemical Industries, Ltd. Procede de production de rfrp
EP1352964A4 (en) * 2000-12-22 2005-02-16 Nippon Soda Co PROCESS FOR PRODUCING A SUBSTANCE USING A MICROBIAL CATALYST
EP1581251B1 (en) * 2002-12-31 2016-03-16 Althea Technologies, Inc. Human growth hormone crystals and methods for preparing them
DE10353973B4 (de) * 2003-11-19 2006-08-17 Beru Ag Verfahren zum Herstellen eines keramischen Glühstiftes für eine keramische Glühkerze
CA2634053A1 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
WO2008095063A1 (en) 2007-01-31 2008-08-07 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
US8592377B2 (en) 2007-03-28 2013-11-26 President And Fellows Of Harvard College Stitched polypeptides
BR112013003248A2 (pt) 2010-08-13 2016-06-07 Aileron Therapeutics Inc "macrociclo peptidomimético e seus usos"
CN104039342A (zh) 2011-10-18 2014-09-10 爱勒让治疗公司 拟肽大环化合物
AU2013221433B2 (en) 2012-02-15 2018-01-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
JP6450191B2 (ja) 2012-02-15 2019-01-09 エイルロン セラピューティクス，インコーポレイテッド ペプチドミメティック大環状化合物
MX2015005244A (es) 2012-11-01 2015-07-14 Aileron Therapeutics Inc Aminoacidos disustituidos y metodos de preparacion y el uso de los mismos.
AU2014310255B2 (en) * 2013-08-21 2017-02-16 Cadila Healthcare Limited Purification process for PTH
JP2017533889A (ja) 2014-09-24 2017-11-16 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用
MX2017011834A (es) 2015-03-20 2018-04-11 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007380A1 (en) 1985-06-04 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing polypeptide
IT1219454B (it) * 1988-02-17 1990-05-18 Serono Cesare Ist Ricerca Metodo di rottura alla metionina di polipeptidi contenenti pontidisolfuro
JPH06316557A (ja) * 1993-03-06 1994-11-15 Fuji Kagaku Kogyo Kk アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤

Also Published As

Publication number Publication date
EP0812856A1 (en) 1997-12-17
DE69700561T2 (de) 2000-05-04
CN1178798A (zh) 1998-04-15
ATE185146T1 (de) 1999-10-15
DE69700561D1 (de) 1999-11-04
KR100478747B1 (ko) 2005-09-08
IL121053A0 (en) 1997-11-20
US6309859B1 (en) 2001-10-30
ES2136458T3 (es) 1999-11-16
US6066470A (en) 2000-05-23
GR3032139T3 (en) 2000-04-27
CA2207723A1 (en) 1997-12-14
KR980002062A (ko) 1998-03-30
CN1158303C (zh) 2004-07-21
EP0812856B1 (en) 1999-09-29
DK0812856T3 (da) 2000-01-03
CA2207723C (en) 2006-12-12

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees