IL121053A - Method for removing N-terminal methionine - Google Patents

Method for removing N-terminal methionine

Info

Publication number
IL121053A
IL121053A IL12105397A IL12105397A IL121053A IL 121053 A IL121053 A IL 121053A IL 12105397 A IL12105397 A IL 12105397A IL 12105397 A IL12105397 A IL 12105397A IL 121053 A IL121053 A IL 121053A
Authority
IL
Israel
Prior art keywords
terminal
methionine residue
terminal methionine
peptide
salt
Prior art date
Application number
IL12105397A
Other languages
English (en)
Other versions
IL121053A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL121053A0 publication Critical patent/IL121053A0/xx
Publication of IL121053A publication Critical patent/IL121053A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Forging (AREA)
IL12105397A 1996-06-14 1997-06-10 Method for removing N-terminal methionine IL121053A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15463496 1996-06-14

Publications (2)

Publication Number Publication Date
IL121053A0 IL121053A0 (en) 1997-11-20
IL121053A true IL121053A (en) 2000-12-06

Family

ID=15588495

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12105397A IL121053A (en) 1996-06-14 1997-06-10 Method for removing N-terminal methionine

Country Status (11)

Country Link
US (2) US6066470A (es)
EP (1) EP0812856B1 (es)
KR (1) KR100478747B1 (es)
CN (1) CN1158303C (es)
AT (1) ATE185146T1 (es)
CA (1) CA2207723C (es)
DE (1) DE69700561T2 (es)
DK (1) DK0812856T3 (es)
ES (1) ES2136458T3 (es)
GR (1) GR3032139T3 (es)
IL (1) IL121053A (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768743B1 (fr) * 1997-09-23 2001-09-14 Bio Merieux Procede de lyse de micro-organisme
DE69941337D1 (de) * 1998-10-05 2009-10-08 Takeda Pharmaceutical Verfahren zum eliminieren von n-terminalem methionin
EP1138772A4 (en) * 1998-12-11 2005-04-06 Takeda Chemical Industries Ltd PROCESS FOR THE PRODUCTION OF APELINE
WO2002046405A1 (fr) * 2000-12-07 2002-06-13 Takeda Chemical Industries, Ltd. Procede de production de rfrp
WO2002052027A1 (en) * 2000-12-22 2002-07-04 Nippon Soda Co., Ltd. Process for producing substance by using microbial catalyst
SG176314A1 (en) * 2002-12-31 2011-12-29 Altus Pharmaceuticals Inc Human growth hormone crystals and methods for preparing them
DE10353973B4 (de) * 2003-11-19 2006-08-17 Beru Ag Verfahren zum Herstellen eines keramischen Glühstiftes für eine keramische Glühkerze
US20090023629A1 (en) * 2005-12-23 2009-01-22 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
KR101623985B1 (ko) 2007-03-28 2016-05-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스티칭된 폴리펩티드
KR102104762B1 (ko) 2010-08-13 2020-04-24 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
CN108929375A (zh) 2011-10-18 2018-12-04 爱勒让治疗公司 拟肽大环化合物
KR102112373B1 (ko) 2012-02-15 2020-05-18 에일러론 테라퓨틱스 인코포레이티드 펩티드모방체 마크로사이클
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES CROSS-LINKED WITH TRIAZOLE AND THIOETHER
KR20150082307A (ko) 2012-11-01 2015-07-15 에일러론 테라퓨틱스 인코포레이티드 이치환 아미노산 및 이의 제조 및 사용 방법
EP3036252A1 (en) * 2013-08-21 2016-06-29 Cadila Healthcare Limited Purification process for pth
CN106999541A (zh) 2014-09-24 2017-08-01 艾瑞朗医疗公司 拟肽大环化合物及其用途
MX2017011834A (es) 2015-03-20 2018-04-11 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
CN115806946B (zh) * 2022-12-20 2025-09-16 深圳瑞德林生物技术有限公司 京都啡肽及其衍生物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007380A1 (fr) 1985-06-04 1986-12-18 Takeda Chemical Industries, Ltd. Procede de preparation de polypeptides
IT1219454B (it) * 1988-02-17 1990-05-18 Serono Cesare Ist Ricerca Metodo di rottura alla metionina di polipeptidi contenenti pontidisolfuro
JPH06316557A (ja) * 1993-03-06 1994-11-15 Fuji Kagaku Kogyo Kk アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤

Also Published As

Publication number Publication date
CN1178798A (zh) 1998-04-15
US6066470A (en) 2000-05-23
ES2136458T3 (es) 1999-11-16
DK0812856T3 (da) 2000-01-03
CA2207723C (en) 2006-12-12
US6309859B1 (en) 2001-10-30
KR100478747B1 (ko) 2005-09-08
DE69700561T2 (de) 2000-05-04
CN1158303C (zh) 2004-07-21
GR3032139T3 (en) 2000-04-27
KR980002062A (ko) 1998-03-30
IL121053A0 (en) 1997-11-20
EP0812856A1 (en) 1997-12-17
DE69700561D1 (de) 1999-11-04
ATE185146T1 (de) 1999-10-15
EP0812856B1 (en) 1999-09-29
CA2207723A1 (en) 1997-12-14

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees