IL119844A - Substituted indole derivatives and pharmaceutical compositions containing them - Google Patents
Substituted indole derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL119844A IL119844A IL11984496A IL11984496A IL119844A IL 119844 A IL119844 A IL 119844A IL 11984496 A IL11984496 A IL 11984496A IL 11984496 A IL11984496 A IL 11984496A IL 119844 A IL119844 A IL 119844A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- indole derivatives
- substituted indole
- substituted
- Prior art date
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9525963A GB2308362A (en) | 1995-12-19 | 1995-12-19 | Pharmaceutical indole derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL119844A0 IL119844A0 (en) | 1997-03-18 |
IL119844A true IL119844A (en) | 2000-12-06 |
Family
ID=10785702
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11984496A IL119844A (en) | 1995-12-19 | 1996-12-17 | Substituted indole derivatives and pharmaceutical compositions containing them |
Country Status (27)
Country | Link |
---|---|
US (1) | US5773448A (de) |
EP (1) | EP0780388B1 (de) |
JP (1) | JPH09202784A (de) |
KR (1) | KR970042503A (de) |
CN (1) | CN1157822A (de) |
AR (1) | AR010205A1 (de) |
AT (1) | ATE204273T1 (de) |
AU (1) | AU720711B2 (de) |
BR (1) | BR9606066A (de) |
CA (1) | CA2193039C (de) |
CZ (1) | CZ372296A3 (de) |
DE (1) | DE69614491T2 (de) |
DK (1) | DK0780388T3 (de) |
ES (1) | ES2159693T3 (de) |
GB (1) | GB2308362A (de) |
HU (1) | HUP9603498A3 (de) |
IL (1) | IL119844A (de) |
MX (1) | MX9606531A (de) |
NO (1) | NO307512B1 (de) |
NZ (1) | NZ299959A (de) |
PE (1) | PE26198A1 (de) |
PL (1) | PL317526A1 (de) |
PT (1) | PT780388E (de) |
SG (1) | SG47206A1 (de) |
TR (1) | TR199601018A1 (de) |
YU (1) | YU67096A (de) |
ZA (1) | ZA9610589B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9810886D0 (en) * | 1998-05-13 | 1998-07-22 | Lilly Industries Ltd | Pharmaceutical compounds |
GB2362826A (en) * | 2000-06-02 | 2001-12-05 | Lilly Co Eli | A pharmaceutical composition comprising a serotonin transport inhibitor and a serotonin recptor antagonist |
US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
WO2017075535A1 (en) | 2015-10-28 | 2017-05-04 | Oxeia Biopharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
CN106928122A (zh) * | 2017-03-07 | 2017-07-07 | 贵州大学 | 3‑烷氧基季碳氧化吲哚及其制备方法 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4411890A (en) * | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4035369A (en) * | 1975-10-08 | 1977-07-12 | Janssen Pharmaceutica N.V. | 1-Benzazolylalkyl-4-substituted-piperidines |
US4432978A (en) * | 1979-07-30 | 1984-02-21 | Pfizer Inc. | Hexahydro-trans-pyridoindole |
US4254127A (en) * | 1980-04-03 | 1981-03-03 | Janssen Pharmaceutica, N.V. | 1,3-Dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives |
FR2523964B1 (fr) * | 1982-03-23 | 1985-09-27 | Sanofi Sa | Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation |
IL69132A (en) * | 1982-07-14 | 1986-02-28 | Roussel Uclaf | Benzo-and naphtho-thiopyranopyrimidinones,their preparation and pharmaceutical compositions containing them |
US4658038A (en) * | 1982-10-07 | 1987-04-14 | Research Foundation For Mental Hygiene, Inc. | N-acylated 5-hydroxytryptophan amide derivatives |
US4608374A (en) * | 1983-11-07 | 1986-08-26 | Hoechst-Roussel Pharmaceuticals Inc. | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents |
GB8332704D0 (en) * | 1983-12-07 | 1984-01-11 | Pfizer Ltd | Growth promotants for animals |
DE3563964D1 (en) * | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
US4789676A (en) * | 1986-03-05 | 1988-12-06 | Merrell Dow Pharmaceuticals Inc. | Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives, usefull as anxiolytic agents |
EP0351283A1 (de) * | 1988-07-12 | 1990-01-17 | Synthelabo | 2-[(4-Piperidinyl)methyl]-2,3-dihydro-1H-isoindol- und 2,3,4,5-tetrahydro-1H-benzazepin-Derivate, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung |
FR2634207B1 (fr) * | 1988-07-12 | 1990-09-07 | Synthelabo | Derives de ((piperidinyl-4)methyl) benzazepines, leur preparation et leur application en therapeutique |
FR2635524B1 (fr) * | 1988-08-19 | 1992-04-24 | Adir | Nouveaux derives de benzopyrrolidinone, leur procede de preparation et les compositions pharmaceutiques les renfermant |
US5068234A (en) * | 1990-02-26 | 1991-11-26 | Sterling Drug Inc. | 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles |
GB9005014D0 (en) * | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
TW203049B (de) * | 1990-04-13 | 1993-04-01 | Yamanouchi Pharma Co Ltd | |
FR2661177A1 (fr) * | 1990-04-23 | 1991-10-25 | Rhone Poulenc Sante | Derives du naphtosultame antagonistes de la serotonine, leur preparation et les medicaments les contenant. |
US5328920A (en) * | 1991-04-17 | 1994-07-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted (pyridinylamino)-indoles |
FR2679561A1 (fr) * | 1991-07-26 | 1993-01-29 | Schneider Marc | Nouveaux derives de l'(indolyl-1) alkylamine substituee par une chaine presentant des groupements carbonyles conjugues a un noyau aromatique. |
SE9103752D0 (sv) | 1991-12-18 | 1991-12-18 | Astra Ab | New compounds |
TW218875B (de) * | 1992-03-09 | 1994-01-11 | Takeda Pharm Industry Co Ltd | |
TW226019B (de) * | 1992-03-23 | 1994-07-01 | Sankyo Co | |
EP0572235A3 (en) * | 1992-05-28 | 1994-06-01 | Tanabe Seiyaku Co | Beta-carboline derivatives with anticholecystoquinine activity |
JPH08503213A (ja) * | 1992-11-06 | 1996-04-09 | メルク エンド カンパニー インコーポレーテッド | 成長ホルモンの放出を促進する置換ジペプチド同族体 |
RO115804B1 (ro) * | 1992-12-11 | 2000-06-30 | Merck & Co Inc | Derivati de spiropiperidine, procedee de preparare si compozitii farmaceutice ale acestora |
US5578593A (en) * | 1992-12-11 | 1996-11-26 | Merck & Co., Inc. | Spiro piperidines and homologs promote release of growth hormone |
CN1052730C (zh) * | 1993-12-23 | 2000-05-24 | 诺沃挪第克公司 | 具有生长激素释放特性的化合物 |
SK281963B6 (sk) * | 1993-12-23 | 2001-09-11 | Novo Nordisk A/S | Zlúčeniny ovplyvňujúce uvoľňovanie rastového hormónu, farmaceutické prostriedky s ich obsahom a ich použitie |
GB9418326D0 (en) * | 1994-09-12 | 1994-11-02 | Lilly Industries Ltd | Pharmaceutical compounds |
ATE247114T1 (de) * | 1994-09-12 | 2003-08-15 | Lilly Co Eli | Serotonergische modulatoren |
US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
-
1995
- 1995-12-19 GB GB9525963A patent/GB2308362A/en not_active Withdrawn
-
1996
- 1996-12-16 PE PE1996000916A patent/PE26198A1/es not_active Application Discontinuation
- 1996-12-16 CA CA002193039A patent/CA2193039C/en not_active Expired - Fee Related
- 1996-12-17 MX MX9606531A patent/MX9606531A/es unknown
- 1996-12-17 PL PL96317526A patent/PL317526A1/xx unknown
- 1996-12-17 TR TR96/01018A patent/TR199601018A1/xx unknown
- 1996-12-17 EP EP96309200A patent/EP0780388B1/de not_active Expired - Lifetime
- 1996-12-17 DE DE69614491T patent/DE69614491T2/de not_active Expired - Fee Related
- 1996-12-17 SG SG1996011771A patent/SG47206A1/en unknown
- 1996-12-17 ZA ZA9610589A patent/ZA9610589B/xx unknown
- 1996-12-17 PT PT96309200T patent/PT780388E/pt unknown
- 1996-12-17 DK DK96309200T patent/DK0780388T3/da active
- 1996-12-17 ES ES96309200T patent/ES2159693T3/es not_active Expired - Lifetime
- 1996-12-17 NZ NZ299959A patent/NZ299959A/en unknown
- 1996-12-17 IL IL11984496A patent/IL119844A/xx not_active IP Right Cessation
- 1996-12-17 YU YU67096A patent/YU67096A/sh unknown
- 1996-12-17 AT AT96309200T patent/ATE204273T1/de not_active IP Right Cessation
- 1996-12-17 AR ARP960105722A patent/AR010205A1/es not_active Application Discontinuation
- 1996-12-18 CN CN96117941A patent/CN1157822A/zh active Pending
- 1996-12-18 BR BR9606066A patent/BR9606066A/pt not_active Application Discontinuation
- 1996-12-18 NO NO965448A patent/NO307512B1/no not_active IP Right Cessation
- 1996-12-18 KR KR1019960067182A patent/KR970042503A/ko not_active Application Discontinuation
- 1996-12-18 CZ CZ963722A patent/CZ372296A3/cs unknown
- 1996-12-18 JP JP8337819A patent/JPH09202784A/ja active Pending
- 1996-12-18 HU HU9603498A patent/HUP9603498A3/hu unknown
- 1996-12-19 AU AU75460/96A patent/AU720711B2/en not_active Ceased
-
1997
- 1997-04-14 US US08/833,239 patent/US5773448A/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
MM9K | Patent not in force due to non-payment of renewal fees |