IL117761A - POLYPEPTIDE HAVING Erythrina Caffra DE-3 INHIBITORY ACTIVITY WHICH REVERSIBLY AND SELECTIVELY BINDS TO SERINE PROTEASES AND ITS USES IN PURIFYING SUCH PROTEASES - Google Patents

POLYPEPTIDE HAVING Erythrina Caffra DE-3 INHIBITORY ACTIVITY WHICH REVERSIBLY AND SELECTIVELY BINDS TO SERINE PROTEASES AND ITS USES IN PURIFYING SUCH PROTEASES

Info

Publication number
IL117761A
IL117761A IL11776196A IL11776196A IL117761A IL 117761 A IL117761 A IL 117761A IL 11776196 A IL11776196 A IL 11776196A IL 11776196 A IL11776196 A IL 11776196A IL 117761 A IL117761 A IL 117761A
Authority
IL
Israel
Prior art keywords
polypeptide
seq
nucleic acid
eti
sequence
Prior art date
Application number
IL11776196A
Other languages
English (en)
Other versions
IL117761A0 (en
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of IL117761A0 publication Critical patent/IL117761A0/xx
Publication of IL117761A publication Critical patent/IL117761A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL11776196A 1995-04-06 1996-04-01 POLYPEPTIDE HAVING Erythrina Caffra DE-3 INHIBITORY ACTIVITY WHICH REVERSIBLY AND SELECTIVELY BINDS TO SERINE PROTEASES AND ITS USES IN PURIFYING SUCH PROTEASES IL117761A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19512937A DE19512937A1 (de) 1995-04-06 1995-04-06 Neuer Inhibitor des Erythrina caffra Typs und dessen Verwendung zur Reinigung von Serinproteasen

Publications (2)

Publication Number Publication Date
IL117761A0 IL117761A0 (en) 1996-08-04
IL117761A true IL117761A (en) 2004-06-20

Family

ID=7758967

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11776196A IL117761A (en) 1995-04-06 1996-04-01 POLYPEPTIDE HAVING Erythrina Caffra DE-3 INHIBITORY ACTIVITY WHICH REVERSIBLY AND SELECTIVELY BINDS TO SERINE PROTEASES AND ITS USES IN PURIFYING SUCH PROTEASES

Country Status (12)

Country Link
US (1) US5973118A (fr)
EP (1) EP0819173B1 (fr)
JP (1) JP3061199B2 (fr)
AT (1) ATE266096T1 (fr)
AU (1) AU5275496A (fr)
CA (1) CA2215531C (fr)
DE (2) DE19512937A1 (fr)
DK (1) DK0819173T3 (fr)
ES (1) ES2219685T3 (fr)
IL (1) IL117761A (fr)
WO (1) WO1996031606A1 (fr)
ZA (1) ZA962707B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3626982B2 (ja) * 1997-08-29 2005-03-09 アークレイ株式会社 タンパク質分解酵素阻害物質の測定方法およびそれに用いる測定キット
US6770457B1 (en) * 1998-05-28 2004-08-03 Korea Green Cross Corporation Process of purifying angiogenesis inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU597908B2 (en) * 1985-10-04 1990-06-14 Implico B.V. A protein reagent having the ability to bind tissue plasminogen activator in its two chain form and/or its single chain form

Also Published As

Publication number Publication date
JPH10505758A (ja) 1998-06-09
DE59611005D1 (de) 2004-06-09
EP0819173A1 (fr) 1998-01-21
ES2219685T3 (es) 2004-12-01
CA2215531C (fr) 2001-12-18
DK0819173T3 (da) 2004-09-13
AU5275496A (en) 1996-10-23
MX9707486A (es) 1997-11-29
JP3061199B2 (ja) 2000-07-10
ATE266096T1 (de) 2004-05-15
DE19512937A1 (de) 1996-10-10
EP0819173B1 (fr) 2004-05-06
WO1996031606A1 (fr) 1996-10-10
IL117761A0 (en) 1996-08-04
US5973118A (en) 1999-10-26
CA2215531A1 (fr) 1996-10-10
ZA962707B (en) 1997-10-06

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