IL117249A - Vaccine compositions comprising hepatitis B antigen 3-O-deacylated monophosphoryl lipid A and aluminum phosphate - Google Patents

Vaccine compositions comprising hepatitis B antigen 3-O-deacylated monophosphoryl lipid A and aluminum phosphate

Info

Publication number
IL117249A
IL117249A IL11724996A IL11724996A IL117249A IL 117249 A IL117249 A IL 117249A IL 11724996 A IL11724996 A IL 11724996A IL 11724996 A IL11724996 A IL 11724996A IL 117249 A IL117249 A IL 117249A
Authority
IL
Israel
Prior art keywords
hepatitis
antigen
aluminum phosphate
vaccine compositions
monophosphoryl lipid
Prior art date
Application number
IL11724996A
Other languages
English (en)
Other versions
IL117249A0 (en
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10770292&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL117249(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of IL117249A0 publication Critical patent/IL117249A0/xx
Publication of IL117249A publication Critical patent/IL117249A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL11724996A 1995-02-25 1996-02-23 Vaccine compositions comprising hepatitis B antigen 3-O-deacylated monophosphoryl lipid A and aluminum phosphate IL117249A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9503863.4A GB9503863D0 (en) 1995-02-25 1995-02-25 Vaccine compositions

Publications (2)

Publication Number Publication Date
IL117249A0 IL117249A0 (en) 1996-06-18
IL117249A true IL117249A (en) 2000-11-21

Family

ID=10770292

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11724996A IL117249A (en) 1995-02-25 1996-02-23 Vaccine compositions comprising hepatitis B antigen 3-O-deacylated monophosphoryl lipid A and aluminum phosphate

Country Status (35)

Country Link
US (1) US5972346A (de)
EP (1) EP0810877B1 (de)
JP (1) JP3881015B2 (de)
KR (1) KR100365373B1 (de)
CN (1) CN1101225C (de)
AP (1) AP766A (de)
AR (1) AR002279A1 (de)
AT (1) ATE209045T1 (de)
AU (1) AU695921B2 (de)
BG (1) BG101851A (de)
BR (1) BR9607458A (de)
CA (1) CA2212552C (de)
CZ (1) CZ288417B6 (de)
DE (1) DE69617211T2 (de)
DK (1) DK0810877T3 (de)
EA (1) EA199700126A1 (de)
ES (1) ES2166879T3 (de)
FI (1) FI118118B (de)
GB (1) GB9503863D0 (de)
HU (1) HU224832B1 (de)
IL (1) IL117249A (de)
MA (1) MA23814A1 (de)
MX (1) MX9706450A (de)
MY (1) MY113428A (de)
NO (1) NO319394B1 (de)
NZ (1) NZ302674A (de)
OA (1) OA10612A (de)
PL (1) PL182679B1 (de)
PT (1) PT810877E (de)
SA (1) SA96160633B1 (de)
SK (1) SK115097A3 (de)
TR (1) TR199700849T1 (de)
TW (1) TW467745B (de)
WO (1) WO1996026741A1 (de)
ZA (1) ZA961460B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6620414B2 (en) * 1992-03-27 2003-09-16 Smithkline Beecham Biologicals (S.A.) Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A
FR2711670B1 (fr) 1993-10-22 1996-01-12 Pasteur Institut Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite.
US6488934B1 (en) * 1995-02-25 2002-12-03 Smithkline Beecham Biologicals S.A. Hepatitis B vaccine
US20010014331A1 (en) * 1996-11-07 2001-08-16 Smithkline Beecham Biologicals S.A. Acellular pertussis vaccine with diphthriae-and tetanus-toxoids
US20030049268A1 (en) 1998-05-01 2003-03-13 Smithkline Beecham Biologicals S.A. Novel composition
GB9809507D0 (en) * 1998-05-01 1998-07-01 Smithkline Beecham Biolog Novel composition
DK1733735T3 (en) 1998-05-22 2017-06-19 Ottawa Hospital Res Inst Methods and products for the induction of mucosal immunity
US6306404B1 (en) 1998-07-14 2001-10-23 American Cyanamid Company Adjuvant and vaccine compositions containing monophosphoryl lipid A
AU750587B2 (en) * 1998-10-16 2002-07-25 Smithkline Beecham Biologicals (Sa) Adjuvant systems and vaccines
CU22871A1 (es) * 1998-12-02 2003-10-21 Ct Ingenieria Genetica Biotech Formulaciones conteniendo partículas semejantes a virus como inmunopotenciadores por vía mucosal
JP2002532116A (ja) * 1998-12-23 2002-10-02 メルク エンド カムパニー インコーポレーテッド 改良された組換えｂ型肝炎表面抗原
CN1227030C (zh) 1999-04-19 2005-11-16 史密丝克莱恩比彻姆生物有限公司 包含皂甙和免疫刺激寡核苷酸的佐剂组合物
US6635261B2 (en) 1999-07-13 2003-10-21 Wyeth Holdings Corporation Adjuvant and vaccine compositions containing monophosphoryl lipid A
CU23031A1 (es) * 2002-01-24 2005-02-23 Ct Ingenieria Genetica Biotech Antigeno de superficie del virus de la hepatitis b como inmunopotenciador mucosal, formulaciones resultantes
CA2598079A1 (en) * 2005-02-16 2006-08-24 Novartis Vaccines And Diagnostics, Inc. Adjuvant composition comprising aluminium phosphate and 3d-mpl
AU2006274647B2 (en) * 2005-08-02 2013-01-10 Novartis Vaccines And Diagnostics Srl Reducing interference between oil-containing adjuvants and surfactant-containing antigens
WO2007052155A2 (en) 2005-11-04 2007-05-10 Novartis Vaccines And Diagnostics Srl Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
NZ567979A (en) 2005-11-04 2012-02-24 Novartis Vaccines & Diagnostic Adjuvanted influenza vaccines including a cytokine-inducing agents which is an agonist of Toll-Like Receptor 7
PL2368572T3 (pl) 2005-11-04 2020-11-16 Seqirus UK Limited Szczepionki z adjuwantem z niewirionowymi antygenami otrzymane z wirusów grypy hodowanych w hodowli komórkowej
ES2377884T3 (es) 2005-11-04 2012-04-02 Novartis Vaccines And Diagnostics S.R.L. Vacunas contra la gripe que incluyen combinaciones de adyuvantes particulados e inmunopotenciadores
CN100415294C (zh) * 2005-12-23 2008-09-03 中国农业大学 一种治疗和/或预防乙肝的药物
BR122019013216B8 (pt) 2006-01-27 2021-07-27 Seqirus Uk Ltd ensaio imunológico para análise de uma vacina contra influenza
WO2007109813A1 (en) 2006-03-23 2007-09-27 Novartis Ag Imidazoquinoxaline compounds as immunomodulators
JP2009534303A (ja) 2006-03-24 2009-09-24 ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー 冷蔵しないインフルエンザワクチンの保存
EP1862176A1 (de) * 2006-05-31 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
EP1862177A1 (de) * 2006-06-01 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
ATE522541T1 (de) 2006-06-09 2011-09-15 Novartis Ag Bakterielle adhäsine konformere
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
EP3456348B1 (de) 2006-09-11 2025-03-26 Seqirus UK Limited Herstellung von influenza-virus-impfstoffen ohne verwendung von eiern
PL2121011T3 (pl) 2006-12-06 2014-10-31 Novartis Ag Szczepionki zawierające antygeny czterech szczepów wirusa grypy
CN101784283A (zh) 2007-06-27 2010-07-21 诺华有限公司 低添加流感疫苗
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
US8685654B2 (en) 2007-12-24 2014-04-01 Novartis Ag Assays for adsorbed influenza vaccines
TW201116294A (en) 2009-07-15 2011-05-16 Novartis Ag RSV F protein compositions and methods for making same
EP4144368B1 (de) 2011-01-26 2025-02-26 GlaxoSmithKline Biologicals S.A. Rsv-immunisierungstherapie
US9452212B2 (en) 2011-04-14 2016-09-27 Dynavax Technologies Corporation Methods and compositions for eliciting an immune response against hepatitis B virus
CN103842374A (zh) 2011-05-13 2014-06-04 诺华股份有限公司 融合前的rsv f抗原
KR20180035807A (ko) 2015-06-26 2018-04-06 세퀴러스 유케이 리미티드 항원적으로 매치된 인플루엔자 백신
JP2022513001A (ja) 2018-11-13 2022-02-07 ヴァリエーション バイオテクノロジーズ インコーポレイテッド Ｂ型肝炎の治療のための免疫原性組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
EP0414374B1 (de) * 1989-07-25 1997-10-08 Smithkline Biologicals S.A. Antigene sowie Verfahren zu deren Herstellung
EP0637223B1 (de) * 1991-05-29 1998-07-22 Origin Medsystems, Inc. Retraktor-vorrichtung fuer endoskopische chirurgie
MA22842A1 (fr) * 1992-03-27 1993-10-01 Smithkline Beecham Biolog Procede de preparation de compositions de vaccin.
DE69319728T2 (de) * 1992-05-23 1999-02-04 Smithkline Beecham Biologicals S.A., Rixensart Kombinierte Impfstoffe, die Hepatitis B oberfläche Antigen und andere Antigenen enthalten
SG48309A1 (en) * 1993-03-23 1998-04-17 Smithkline Beecham Biolog Vaccine compositions containing 3-0 deacylated monophosphoryl lipid a
GB9311536D0 (en) * 1993-06-04 1993-07-21 Unilever Plc Hot soluble low density extractable food product

Also Published As

Publication number Publication date
FI973457A0 (fi) 1997-08-22
NZ302674A (en) 1999-01-28
AP9701060A0 (en) 1997-10-31
CA2212552A1 (en) 1996-09-06
GB9503863D0 (en) 1995-04-19
DK0810877T3 (da) 2002-02-25
PL182679B1 (pl) 2002-02-28
KR100365373B1 (ko) 2003-07-07
CZ267497A3 (cs) 1998-02-18
WO1996026741A1 (en) 1996-09-06
NO973873L (no) 1997-08-22
HUP9801242A1 (hu) 1998-08-28
EP0810877B1 (de) 2001-11-21
OA10612A (en) 2002-08-29
FI973457L (fi) 1997-08-22
TW467745B (en) 2001-12-11
BG101851A (en) 1998-04-30
HK1004117A1 (en) 1998-11-20
DE69617211T2 (de) 2002-07-25
DE69617211D1 (en) 2002-01-03
PT810877E (pt) 2002-04-29
ES2166879T3 (es) 2002-05-01
ATE209045T1 (de) 2001-12-15
ZA961460B (en) 1996-08-29
SK115097A3 (en) 1998-02-04
MX9706450A (es) 1998-07-31
EA199700126A1 (ru) 1998-02-26
SA96160633B1 (ar) 2005-10-15
US5972346A (en) 1999-10-26
TR199700849T1 (xx) 1998-01-21
AR002279A1 (es) 1998-03-11
NO973873D0 (no) 1997-08-22
AU4878096A (en) 1996-09-18
AU695921B2 (en) 1998-08-27
NO319394B1 (no) 2005-08-08
EP0810877A1 (de) 1997-12-10
KR19980702480A (ko) 1998-07-15
CN1101225C (zh) 2003-02-12
CZ288417B6 (en) 2001-06-13
PL321966A1 (en) 1998-01-05
HU224832B1 (en) 2006-03-28
MA23814A1 (fr) 1996-10-01
JPH11501018A (ja) 1999-01-26
AP766A (en) 1999-09-17
IL117249A0 (en) 1996-06-18
HUP9801242A3 (en) 2000-08-28
MY113428A (en) 2002-02-28
JP3881015B2 (ja) 2007-02-14
BR9607458A (pt) 1998-06-30
CN1176604A (zh) 1998-03-18
FI118118B (fi) 2007-07-13
CA2212552C (en) 2006-07-11

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