IL116310A - Alkyl-substituted piperidinyl and piperazinyl anti-AIDS compounds - Google Patents

Alkyl-substituted piperidinyl and piperazinyl anti-AIDS compounds

Info

Publication number
IL116310A
IL116310A IL11631095A IL11631095A IL116310A IL 116310 A IL116310 A IL 116310A IL 11631095 A IL11631095 A IL 11631095A IL 11631095 A IL11631095 A IL 11631095A IL 116310 A IL116310 A IL 116310A
Authority
IL
Israel
Prior art keywords
piperazinyl
alkyl
substituted piperidinyl
aids compounds
aids
Prior art date
Application number
IL11631095A
Other languages
English (en)
Other versions
IL116310A0 (en
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26998606&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL116310(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL116310A0 publication Critical patent/IL116310A0/xx
Publication of IL116310A publication Critical patent/IL116310A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL11631095A 1994-12-13 1995-12-10 Alkyl-substituted piperidinyl and piperazinyl anti-AIDS compounds IL116310A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35492594A 1994-12-13 1994-12-13
US40009595A 1995-03-07 1995-03-07

Publications (2)

Publication Number Publication Date
IL116310A0 IL116310A0 (en) 1996-03-31
IL116310A true IL116310A (en) 2000-08-31

Family

ID=26998606

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11631095A IL116310A (en) 1994-12-13 1995-12-10 Alkyl-substituted piperidinyl and piperazinyl anti-AIDS compounds

Country Status (10)

Country Link
US (1) US5866589A (xx)
EP (1) EP0797576A1 (xx)
JP (1) JPH10510530A (xx)
AR (1) AR003106A1 (xx)
AU (1) AU4151696A (xx)
CO (1) CO4700295A1 (xx)
IL (1) IL116310A (xx)
PE (1) PE55596A1 (xx)
TW (1) TW406075B (xx)
WO (1) WO1996018628A1 (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9811557A (pt) * 1997-08-15 2000-08-22 Pfizer Prod Inc Derivados do 2-)4-aril ou heteroaril-piperazin-1-ilmetil)-1h-indol
US6251919B1 (en) * 1998-02-27 2001-06-26 Warner-Lambert Heterocyclic substituted aniline calcium channel blockers
SE9803773D0 (sv) * 1998-11-05 1998-11-05 Astra Pharma Prod Compounds
GB0016453D0 (en) * 2000-07-04 2000-08-23 Hoffmann La Roche Pyrrole derivatives
HU227197B1 (en) * 2000-10-24 2010-10-28 Richter Gedeon Nyrt Nmda receptor antagonist carboxylic acid amide derivatives and pharmaceutical compositions containing them
PT1363705E (pt) * 2001-02-02 2012-08-17 Bristol Myers Squibb Co Composição e actividade antiviral de derivados de piperazina azaindoleoxoacética substituídos
JP2005509032A (ja) * 2001-11-14 2005-04-07 シェーリング　コーポレイション カンナビノイドレセプターリガンド
US20050215614A1 (en) * 2002-10-15 2005-09-29 Rigel Pharmaceuticals, Inc. Substituted indoles and their use as hcv inhibitors
US20050075364A1 (en) * 2003-07-01 2005-04-07 Kap-Sun Yeung Indole, azaindole and related heterocyclic N-substituted piperazine derivatives
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
US8247442B2 (en) * 2006-03-29 2012-08-21 Purdue Pharma L.P. Benzenesulfonamide compounds and their use
US8791264B2 (en) * 2006-04-13 2014-07-29 Purdue Pharma L.P. Benzenesulfonamide compounds and their use as blockers of calcium channels
TW200812963A (en) * 2006-04-13 2008-03-16 Euro Celtique Sa Benzenesulfonamide compounds and the use thereof
JO2642B1 (en) * 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) * 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
US8399486B2 (en) * 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
DK2148873T3 (da) 2007-04-23 2012-11-26 Janssen Pharmaceutica Nv 4-alkoxypyridazinderivater som hurtigt dissocierende dopamin 2- receptorantagonister
EP2148872A1 (en) * 2007-04-23 2010-02-03 Janssen Pharmaceutica, N.V. Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
AU2008240729B2 (en) 2007-04-23 2012-08-23 Janssen Pharmaceutica N.V. Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
WO2009040659A2 (en) * 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
CN101896481B (zh) * 2007-10-16 2014-04-30 第一三共株式会社 嘧啶基二氢吲哚化合物
ES2398625T3 (es) 2008-07-03 2013-03-20 Janssen Pharmaceutica N.V. 6-(1-Piperazinil)-piritazinas sustituidas como antagonistas de receptores 5-HT6
ES2622161T3 (es) * 2008-07-31 2017-07-05 Janssen Pharmaceutica, N.V. Piridinas sustituidas con piperazin-1-il-trifluorometilo como antagonistas del receptor de la dopamina 2 de disociación rápida
CN106573893B (zh) 2014-07-31 2020-06-09 巴斯夫欧洲公司 制备吡唑的方法
PE20180327A1 (es) 2015-05-11 2018-02-13 Basf Se Proceso para preparar 4-amino-piridazinas
WO2018082964A1 (en) 2016-11-04 2018-05-11 Basf Se Process for the production of pyridazinyl-amides in a one-pot synthesis
CN114605303A (zh) * 2022-03-14 2022-06-10 武汉工程大学 一种地拉韦啶及其中间体的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3686188A (en) * 1970-06-30 1972-08-22 Ciba Geigy Corp N-benzofurylmethyl-arylalkyleneimines
DK0507861T3 (xx) * 1989-12-28 1997-03-03 Upjohn Co
US5563142A (en) * 1989-12-28 1996-10-08 The Upjohn Company Diaromatic substituted compounds as anti-HIV-1 agents
WO1992018089A2 (en) * 1991-04-09 1992-10-29 The Upjohn Company Use of steroidal and non-steroidal amines to sensitize multidrug-resistant cells
WO1993001181A1 (en) * 1991-07-03 1993-01-21 The Upjohn Company Substituted indoles as anti-aids pharmaceuticals
DE4307883A1 (en) * 1992-03-12 1993-09-23 Westarp Martin Egon Dr Med Use of anti-retroviral substances - to treat motor-neuronal diseases
WO1994009781A1 (en) * 1992-10-28 1994-05-11 The Upjohn Company Use of bhap compounds in combination with other non-nucleoside reverse transcriptase inhibitors for the treatment of hiv infection
EP0757398A1 (de) * 1995-07-25 1997-02-05 DORNIER GmbH Anordnung von mehreren Brennstoffzellen-Stacks zu einem Modul

Also Published As

Publication number Publication date
IL116310A0 (en) 1996-03-31
CO4700295A1 (es) 1998-12-29
TW406075B (en) 2000-09-21
US5866589A (en) 1999-02-02
AU4151696A (en) 1996-07-03
JPH10510530A (ja) 1998-10-13
WO1996018628A1 (en) 1996-06-20
EP0797576A1 (en) 1997-10-01
AR003106A1 (es) 1998-07-08
PE55596A1 (es) 1996-12-11

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees