|
US6015668A
(en)
*
|
1994-09-30 |
2000-01-18 |
Life Technologies, Inc. |
Cloned DNA polymerases from thermotoga and mutants thereof
|
|
US5912155A
(en)
*
|
1994-09-30 |
1999-06-15 |
Life Technologies, Inc. |
Cloned DNA polymerases from Thermotoga neapolitana
|
|
US6077664A
(en)
*
|
1995-06-07 |
2000-06-20 |
Promega Corporation |
Thermophilic DNA polymerases from Thermotoga neapolitana
|
|
US20050112637A1
(en)
*
|
1995-09-08 |
2005-05-26 |
Chatterjee Deb K. |
Mutant DNA polymerases and uses thereof
|
|
WO1997009451A1
(fr)
*
|
1995-09-08 |
1997-03-13 |
Life Technologies, Inc. |
Adn polymerases clonees tirees de thermotoga et mutants de ces polymerases
|
|
US6165765A
(en)
*
|
1995-10-18 |
2000-12-26 |
Shanghai Institute Of Biochemistry, Chinese Academy Of Sciences |
DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides
|
|
US6818431B1
(en)
|
1995-10-18 |
2004-11-16 |
Shanghai Mendel Dna Center Co. Ltd. |
DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides
|
|
US5972603A
(en)
*
|
1996-02-09 |
1999-10-26 |
President And Fellows Of Harvard College |
DNA polymerase with modified processivity
|
|
DE19612684A1
(de)
*
|
1996-03-29 |
1997-10-02 |
Gsf Forschungszentrum Umwelt |
Neue Verwendung extrem thermophiler DNA-Polymerasen
|
|
US6214555B1
(en)
*
|
1996-05-01 |
2001-04-10 |
Visible Genetics Inc. |
Method compositions and kit for detection
|
|
CZ293215B6
(cs)
*
|
1996-08-06 |
2004-03-17 |
F. Hoffmann-La Roche Ag |
Rekombinantní tepelně stálá DNA polymeráza, způsob její přípravy a prostředek, který ji obsahuje
|
|
US5885775A
(en)
*
|
1996-10-04 |
1999-03-23 |
Perseptive Biosystems, Inc. |
Methods for determining sequences information in polynucleotides using mass spectrometry
|
|
WO1998023733A2
(fr)
*
|
1996-11-27 |
1998-06-04 |
University Of Washington |
Polymerases thermostables presentant une fidelite modifiee
|
|
FR2757178B1
(fr)
*
|
1996-12-13 |
1999-03-05 |
Centre Nat Rech Scient |
Utilisation d'un vecteur exprimant l'adn polymerase beta comme medicament
|
|
DE19653439A1
(de)
*
|
1996-12-20 |
1998-07-02 |
Svante Dr Paeaebo |
Verfahren zur direkten, exponentiellen Amplifikation und Sequenzierung von DNA Molekülen und dessen Anwendung
|
|
US6399304B1
(en)
|
1996-12-20 |
2002-06-04 |
Roche Diagnostics Gmbh |
Sequential activation of one or more enzymatic activities within a thermocycling reaction for synthesizing DNA molecules
|
|
US6828094B2
(en)
*
|
1996-12-20 |
2004-12-07 |
Roche Diagnostics Gmbh |
Method for the uncoupled, direct, exponential amplification and sequencing of DNA molecules with the addition of a second thermostable DNA polymerase and its application
|
|
US6605428B2
(en)
*
|
1996-12-20 |
2003-08-12 |
Roche Diagnostics Gmbh |
Method for the direct, exponential amplification and sequencing of DNA molecules and its application
|
|
DE19653494A1
(de)
*
|
1996-12-20 |
1998-06-25 |
Svante Dr Paeaebo |
Verfahren zur entkoppelten, direkten, exponentiellen Amplifikation und Sequenzierung von DNA Molekülen unter Zugabe einer zweiten thermostabilen DNA Polymerase und dessen Anwendung
|
|
US6306588B1
(en)
*
|
1997-02-07 |
2001-10-23 |
Invitrogen Corporation |
Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
|
|
EP1247866B1
(fr)
|
1997-03-12 |
2009-07-29 |
Applied Biosystems, LLC |
ADN polymérases présentant des propriétés améliorées d'incorporation de nucléotides marqués
|
|
DE69841023D1
(de)
*
|
1997-03-12 |
2009-09-10 |
Applied Biosystems Llc |
DNA Polymerasen mit verbesserten Fähigkeiten zum Einbau von markierten Nukleotiden
|
|
US6355417B2
(en)
*
|
1997-03-14 |
2002-03-12 |
Transgenomic, Inc. |
Band array display of polynucleotide separations
|
|
JP3318579B2
(ja)
*
|
1997-07-07 |
2002-08-26 |
理化学研究所 |
Dnaの塩基配列決定方法
|
|
JP3172710B2
(ja)
*
|
1997-07-07 |
2001-06-04 |
理化学研究所 |
Rnaポリメラーゼ
|
|
US6228628B1
(en)
|
1997-07-09 |
2001-05-08 |
Roche Molecular Systems |
Mutant chimeric DNA polymerase
|
|
US5882904A
(en)
*
|
1997-08-04 |
1999-03-16 |
Amersham Pharmacia Biotech Inc. |
Thermococcus barossii DNA polymerase mutants
|
|
ATE502043T1
(de)
|
1997-08-29 |
2011-04-15 |
Life Technologies Corp |
Hochempfindliche polymerasen und ihre verwendungen
|
|
US6346379B1
(en)
*
|
1997-09-11 |
2002-02-12 |
F. Hoffman-La Roche Ag |
Thermostable DNA polymerases incorporating nucleoside triphosphates labeled with fluorescein family dyes
|
|
EP1025217B1
(fr)
*
|
1997-10-24 |
2006-10-04 |
Invitrogen Corporation |
Clonage recombinatoire au moyen d'acides nucleiques possedant des sites de recombinaison
|
|
ATE299190T1
(de)
*
|
1998-02-04 |
2005-07-15 |
Amersham Biosciences Corp |
Didesoxy farbterminatoren
|
|
US6787305B1
(en)
|
1998-03-13 |
2004-09-07 |
Invitrogen Corporation |
Compositions and methods for enhanced synthesis of nucleic acid molecules
|
|
NZ512244A
(en)
|
1998-11-12 |
2003-12-19 |
Invitrogen Corp |
Polycationic transfection reagents for introducing anions into a cell
|
|
AU2505000A
(en)
*
|
1999-01-15 |
2000-08-01 |
Myriad Genetics, Inc. |
Method for controlling the distribution of dna sequencing termination products
|
|
GB9907813D0
(en)
*
|
1999-04-06 |
1999-06-02 |
Medical Biosystems Ltd |
Synthesis
|
|
EP1175501A4
(fr)
*
|
1999-05-12 |
2002-11-27 |
Invitrogen Corp |
Compositions et methodes d'amelioration de la sensibilite et de la specificite d'une synthese d'acide nucleique
|
|
WO2000079009A2
(fr)
|
1999-06-22 |
2000-12-28 |
Invitrogen Corporation |
Amorces et procedes ameliores destines a la detection et a la discrimination d'acides nucleiques
|
|
US6830902B1
(en)
|
1999-07-02 |
2004-12-14 |
Invitrogen Corporation |
Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
|
|
JP2003510063A
(ja)
*
|
1999-09-30 |
2003-03-18 |
ニュー・イングランド・バイオラブズ・インコーポレイティッド |
古細菌のdnaポリメラーゼによる修飾ヌクレオチドの取り込み及びそれに関する方法
|
|
US20040009486A1
(en)
|
1999-10-29 |
2004-01-15 |
Sorge Joseph A. |
Compositions and methods utilizing DNA polymerases
|
|
DE60027040T2
(de)
*
|
1999-10-29 |
2006-11-23 |
Stratagene California, La Jolla |
Zusammensetzungen und methoden zur verwendung von dna polymerasen
|
|
WO2001038546A1
(fr)
*
|
1999-11-23 |
2001-05-31 |
Amersham Biosciences Corp |
Utilisation amelioree de didesoxynucleotide triphosphate par l'adn polymerase hyperthermophile issu de l'archaeon pyrococcus furiosus
|
|
NZ539430A
(en)
|
1999-12-10 |
2006-09-29 |
Invitrogen Corp |
Use of multiple recombination sites with unique specificity in recombinational cloning
|
|
US7179590B2
(en)
*
|
2000-04-18 |
2007-02-20 |
Roche Molecular Systems, Inc |
High temperature reverse transcription using mutant DNA polymerases
|
|
US7198924B2
(en)
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
|
US6548251B1
(en)
|
2000-09-05 |
2003-04-15 |
Fidelity Systems, Inc. |
Inhibition of molecular and biological processes using modified oligonucleotides
|
|
AU2001296645A1
(en)
|
2000-10-06 |
2002-04-15 |
The Trustees Of Columbia University In The City Of New York |
Massive parallel method for decoding dna and rna
|
|
AU2715302A
(en)
|
2000-12-08 |
2002-06-18 |
Invitrogen Corp |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
|
WO2002073504A1
(fr)
*
|
2001-03-14 |
2002-09-19 |
Gene Logic, Inc. |
Systeme et procede d'extraction et d'utilisation de donnees d'expression genique provenant de multiples sources
|
|
US20050042629A1
(en)
|
2002-09-13 |
2005-02-24 |
Applera Corporation |
Thermus scotoductus nucleic acid polymerases
|
|
US20070020622A1
(en)
*
|
2001-09-14 |
2007-01-25 |
Invitrogen Corporation |
DNA Polymerases and mutants thereof
|
|
US20030165859A1
(en)
*
|
2001-10-23 |
2003-09-04 |
Invitrogen Corporation |
Primers and methods for the detection and discrimination of nucleic acids
|
|
JP4210769B2
(ja)
*
|
2001-11-22 |
2009-01-21 |
独立行政法人産業技術総合研究所 |
Gatewayエントリークローンの作製方法
|
|
EP1456394B2
(fr)
|
2001-11-28 |
2011-04-27 |
Bio-Rad Laboratories, Inc. |
Procedes d'utilisation de polymerases ameliorees
|
|
US20030194726A1
(en)
*
|
2001-11-30 |
2003-10-16 |
Applera Corporation |
Thermus oshimai nucleic acid polymerases
|
|
JP2005511043A
(ja)
|
2001-11-30 |
2005-04-28 |
アプレラ コーポレイション |
Thermusthermophilus核酸ポリメラーゼ
|
|
US7052877B2
(en)
|
2001-11-30 |
2006-05-30 |
Applera Corporation |
Thermus brockianus nucleic acid polymerases
|
|
WO2003057910A2
(fr)
|
2002-01-08 |
2003-07-17 |
Roche Diagnostics Gmbh |
Utilisation d'un materiau de silice dans une reaction d'amplification
|
|
US20030228589A1
(en)
*
|
2002-02-12 |
2003-12-11 |
Bond-Nutter Diane R. |
Polymerase compositions
|
|
US7148049B2
(en)
|
2002-04-02 |
2006-12-12 |
Roche Molecular Systems, Inc. |
Thermostable or thermoactive DNA polymerase molecules with attenuated 3′-5′ exonuclease activity
|
|
US20040132133A1
(en)
*
|
2002-07-08 |
2004-07-08 |
Invitrogen Corporation |
Methods and compositions for the production, identification and purification of fusion proteins
|
|
EP1539209A2
(fr)
*
|
2002-09-05 |
2005-06-15 |
Invitrogen Corporation |
Compositions et procedes de synthese d'acides nucleiques
|
|
US20040126765A1
(en)
*
|
2002-12-27 |
2004-07-01 |
Adams Craig W. |
Method and compositions for sequencing nucleic acid molecules
|
|
AU2004225520A1
(en)
|
2003-03-25 |
2004-10-14 |
Stratagene |
DNA polymerase fusions and uses thereof
|
|
EP2216415B2
(fr)
*
|
2003-08-01 |
2017-01-04 |
Life Technologies Corporation |
Compositions et procédés de préparation de courtes molécules d'ARN et d'autres acides nucléiques
|
|
US7179602B2
(en)
*
|
2003-09-04 |
2007-02-20 |
Los Alamos National Security, Llc |
Methods for sequencing GC-rich and CCT repeat DNA templates
|
|
WO2005054438A2
(fr)
*
|
2003-12-01 |
2005-06-16 |
Invitrogen Corporation |
Molecule d'acide nucleique contenant des sites de recombinaison et leurs procedes d'utilisation
|
|
US20050196392A1
(en)
*
|
2004-02-20 |
2005-09-08 |
Andersen Mark R. |
Lesion repair polymerase compositions
|
|
WO2005113147A2
(fr)
|
2004-04-08 |
2005-12-01 |
Biomatrica, Inc. |
Integration du stockage et de la gestion d'echantillons pour les sciences de la vie
|
|
US20080176209A1
(en)
*
|
2004-04-08 |
2008-07-24 |
Biomatrica, Inc. |
Integration of sample storage and sample management for life science
|
|
US20060099567A1
(en)
*
|
2004-04-08 |
2006-05-11 |
Biomatrica, Inc. |
Integration of sample storage and sample management for life science
|
|
US20070048748A1
(en)
*
|
2004-09-24 |
2007-03-01 |
Li-Cor, Inc. |
Mutant polymerases for sequencing and genotyping
|
|
US20060105348A1
(en)
*
|
2004-11-15 |
2006-05-18 |
Lee Jun E |
Compositions and methods for the detection and discrimination of nucleic acids
|
|
US20060275792A1
(en)
*
|
2004-11-15 |
2006-12-07 |
Lee Jun E |
Enhancement of nucleic acid amplification using double-stranded DNA binding proteins
|
|
BRPI0515777A
(pt)
*
|
2004-12-11 |
2008-08-05 |
Cytogenix Inc |
biossìntese isenta de células de ácido nucléico de alta qualidade e usos dos mesmos
|
|
US20060228726A1
(en)
*
|
2005-01-06 |
2006-10-12 |
Martin Patrick K |
Polypeptides having nucleic acid binding activity and compositions and methods for nucleic acid amplification
|
|
US9505846B2
(en)
*
|
2005-01-28 |
2016-11-29 |
Life Technologies Corporation |
Multi-component inhibitors of nucleic acid polymerases
|
|
US20060223067A1
(en)
*
|
2005-03-31 |
2006-10-05 |
Paolo Vatta |
Mutant DNA polymerases and methods of use
|
|
US20060292578A1
(en)
*
|
2005-06-28 |
2006-12-28 |
Weidong Zheng |
DNA polymerase blends and mutant DNA polymerases
|
|
US20070059713A1
(en)
*
|
2005-09-09 |
2007-03-15 |
Lee Jun E |
SSB-DNA polymerase fusion proteins
|
|
US20100260465A1
(en)
*
|
2005-12-22 |
2010-10-14 |
Pacific Biosciences Of California, Inc. |
Protein engineering strategies to optimize activity of surface attached proteins
|
|
WO2007075987A2
(fr)
*
|
2005-12-22 |
2007-07-05 |
Pacific Biosciences Of California, Inc. |
Polymérases actives couplées à des surfaces
|
|
EP1914303A1
(fr)
*
|
2006-10-09 |
2008-04-23 |
Qiagen GmbH |
ADN polymerases de Thermus eggertssonii
|
|
EP1970440A1
(fr)
*
|
2007-03-06 |
2008-09-17 |
Qiagen GmbH |
Stabilisation de polymérase par des détergents ioniques
|
|
CA2684959A1
(fr)
*
|
2007-04-24 |
2009-01-15 |
Biomatrica, Inc. |
Stockage d'echantillon pour sciences biologiques
|
|
US20080274458A1
(en)
*
|
2007-05-01 |
2008-11-06 |
Latham Gary J |
Nucleic acid quantitation methods
|
|
WO2009087394A1
(fr)
*
|
2008-01-11 |
2009-07-16 |
Genesys Ltd |
Protéine chimérique cren7
|
|
GB0803628D0
(en)
*
|
2008-02-28 |
2008-04-02 |
Genesys Ltd |
Enzyme
|
|
GB0804722D0
(en)
*
|
2008-03-14 |
2008-04-16 |
Genesys Ltd |
Enzyme
|
|
GB0804721D0
(en)
*
|
2008-03-14 |
2008-04-16 |
Genesys Ltd |
Enzyme
|
|
US9127259B2
(en)
*
|
2008-03-31 |
2015-09-08 |
Pacific Biosciences Of California, Inc. |
Enzymes resistant to photodamage
|
|
WO2010051434A1
(fr)
*
|
2008-10-31 |
2010-05-06 |
Helicos Biosciences Corporation |
Polymérases et leurs procédés d'utilisation
|
|
US20100330556A1
(en)
*
|
2009-06-30 |
2010-12-30 |
Brian Jon Peter |
Genome analysis using a nicking endonuclease
|
|
US9428737B1
(en)
*
|
2010-01-11 |
2016-08-30 |
Eric Gaucher |
Taq polymerase sequences useful for incorporating analogs of nucleoside triphosphates
|
|
EP2392680A1
(fr)
|
2010-06-04 |
2011-12-07 |
Labor Diagnostik GmbH Leipzig |
Procédé pour la détection spécifique de virus recombinant de la peste porcine
|
|
EP2582850B1
(fr)
|
2010-06-21 |
2016-11-09 |
Life Technologies Corporation |
Compositions, trousses et procédés pour la synthèse et/ou la détection d'acides nucléiques
|
|
WO2012018639A2
(fr)
|
2010-07-26 |
2012-02-09 |
Biomatrica, Inc. |
Compositions de stabilisation d'adn, d'arn, de protéines salivaires et d'autres échantillons biologiques lors du transport et du stockage à températures ambiantes
|
|
EP2598660B1
(fr)
|
2010-07-26 |
2017-03-15 |
Biomatrica, INC. |
Compositions de stabilisation d'adn, d'arn, de protéines dans le sang et d'autres échantillons biologiques lors du transport et du stockage à températures ambiantes
|
|
US10301674B2
(en)
|
2010-08-20 |
2019-05-28 |
Life Technologies Corporation |
Polymerase assay with a FRET substrate
|
|
WO2012024642A1
(fr)
|
2010-08-20 |
2012-02-23 |
Life Technologies Corporation |
Dosage d'amplification en chaîne par polymérase en temps réel utilisant des amorces à double marquage de transfert d'énergie par résonance de fluorescence
|
|
US8932813B2
(en)
|
2010-12-13 |
2015-01-13 |
Life Technologies Corporation |
Polymerization of nucleic acids using activation by polyphosphorolysis (APP) reactions
|
|
US8715987B2
(en)
|
2011-05-02 |
2014-05-06 |
New England Biolabs, Inc. |
Solubilized phospholipids for stabilizing nucleic acid polymerases
|
|
US8663919B2
(en)
|
2011-05-18 |
2014-03-04 |
Life Technologies Corporation |
Chromosome conformation analysis
|
|
US10323236B2
(en)
|
2011-07-22 |
2019-06-18 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
GB201113430D0
(en)
|
2011-08-03 |
2011-09-21 |
Fermentas Uab |
DNA polymerases
|
|
US11208636B2
(en)
|
2011-08-10 |
2021-12-28 |
Life Technologies Corporation |
Polymerase compositions, methods of making and using same
|
|
US20130040365A1
(en)
|
2011-08-10 |
2013-02-14 |
Life Technologies Corporation |
Polymerase compositions, methods of making and using same
|
|
DK2914741T3
(da)
|
2012-11-02 |
2017-11-20 |
Life Technologies Corp |
Hidtil ukendte sammensætninger og fremgangsmåder til forbedring af PCR-specificitet
|
|
US9725703B2
(en)
|
2012-12-20 |
2017-08-08 |
Biomatrica, Inc. |
Formulations and methods for stabilizing PCR reagents
|
|
EP2971095B1
(fr)
|
2013-03-12 |
2019-11-20 |
Life Technologies Corporation |
Procédés de génotypage fondés sur des indicateurs universels, et mixtures et trousses appropriés
|
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
|
US9228207B2
(en)
|
2013-09-06 |
2016-01-05 |
President And Fellows Of Harvard College |
Switchable gRNAs comprising aptamers
|
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
|
ES2786373T3
(es)
|
2014-06-10 |
2020-10-09 |
Biomatrica Inc |
Estabilización de trombocitos a temperaturas ambiente
|
|
EP3169310A1
(fr)
|
2014-07-15 |
2017-05-24 |
Life Technologies Corporation |
Compositions comprenant des agrégats lipidiques et procédés d'administration efficace de molécules dans des cellules
|
|
US10077453B2
(en)
|
2014-07-30 |
2018-09-18 |
President And Fellows Of Harvard College |
CAS9 proteins including ligand-dependent inteins
|
|
CN107109474B
(zh)
|
2014-08-19 |
2021-03-19 |
豪夫迈·罗氏有限公司 |
用于核酸检测的方法和组合物
|
|
US10329545B2
(en)
|
2014-11-14 |
2019-06-25 |
Illumina, Inc. |
Polymerases
|
|
EP3967768A1
(fr)
|
2015-03-13 |
2022-03-16 |
Life Technologies Corporation |
Compositions pour la capture, la détection et la quantification de petit nra
|
|
US10077470B2
(en)
|
2015-07-21 |
2018-09-18 |
Omniome, Inc. |
Nucleic acid sequencing methods and systems
|
|
IL310721B2
(en)
|
2015-10-23 |
2025-11-01 |
Harvard College |
Nucleobase editors and uses thereof
|
|
KR20250047404A
(ko)
|
2015-12-08 |
2025-04-03 |
바이오매트리카 인코포레이티드 |
적혈구 침강 속도의 감소
|
|
EP3449012B1
(fr)
|
2016-04-29 |
2020-12-23 |
Omniome, Inc. |
Procédé de séquençage faisant appel à la déstabilisation d'un complexe ternaire pour identifier des nucléotides apparentés
|
|
US20170362640A1
(en)
|
2016-06-16 |
2017-12-21 |
Life Technologies Corporation |
Novel compositions, methods and kits for microorganism detection
|
|
CN110214183A
(zh)
|
2016-08-03 |
2019-09-06 |
哈佛大学的校长及成员们 |
腺苷核碱基编辑器及其用途
|
|
WO2018031683A1
(fr)
|
2016-08-09 |
2018-02-15 |
President And Fellows Of Harvard College |
Protéines de fusion cas9-recombinase programmables et utilisations associées
|
|
US10428378B2
(en)
|
2016-08-15 |
2019-10-01 |
Omniome, Inc. |
Sequencing method for rapid identification and processing of cognate nucleotide pairs
|
|
EP3497236B1
(fr)
|
2016-08-15 |
2021-11-03 |
Omniome, Inc. |
Procédé de séquençage d'acides nucléiques
|
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
US11613777B2
(en)
|
2016-08-26 |
2023-03-28 |
Life Technologies Corporation |
Nucleic acid extraction and amplification controls and methods of use thereof
|
|
KR102622411B1
(ko)
|
2016-10-14 |
2024-01-10 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵염기 에디터의 aav 전달
|
|
WO2018119359A1
(fr)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Édition du gène récepteur ccr5 pour protéger contre l'infection par le vih
|
|
EP3562962B1
(fr)
|
2016-12-30 |
2022-01-05 |
Omniome, Inc. |
Procédé et système utilisant des polymérases pouvant être distinguées pour détecter des complexes ternaires et identifier des nucléotides parents
|
|
WO2018136487A1
(fr)
|
2017-01-20 |
2018-07-26 |
Omniome, Inc. |
Procédé de détection de nucléotides apparentés dans un flux de travaux de séquençage d'acides nucléiques
|
|
US12390514B2
(en)
|
2017-03-09 |
2025-08-19 |
President And Fellows Of Harvard College |
Cancer vaccine
|
|
EP3592853A1
(fr)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Suppression de la douleur par édition de gène
|
|
US11542496B2
(en)
|
2017-03-10 |
2023-01-03 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
|
KR20240116572A
(ko)
|
2017-03-23 |
2024-07-29 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제
|
|
US9951385B1
(en)
|
2017-04-25 |
2018-04-24 |
Omniome, Inc. |
Methods and apparatus that increase sequencing-by-binding efficiency
|
|
US10161003B2
(en)
|
2017-04-25 |
2018-12-25 |
Omniome, Inc. |
Methods and apparatus that increase sequencing-by-binding efficiency
|
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
|
EP3676376B1
(fr)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
Éditeurs de bases à haut rendement comprenant une gam
|
|
KR20250107288A
(ko)
|
2017-10-16 |
2025-07-11 |
더 브로드 인스티튜트, 인코퍼레이티드 |
아데노신 염기 편집제의 용도
|
|
EP3697932A1
(fr)
|
2017-10-19 |
2020-08-26 |
Omniome, Inc. |
Réduction du bruit de fond et stabilisation de complexes simultanées dans des flux de travaux de dosage par liaison
|
|
WO2019094973A1
(fr)
|
2017-11-13 |
2019-05-16 |
Life Technologies Corporation |
Compositions, procédés et kits de détection de micro-organismes dans les voies urinaires
|
|
KR102190629B1
(ko)
*
|
2017-11-21 |
2020-12-14 |
(주)나노헬릭스 |
중합효소 반응용 조성물
|
|
US12406749B2
(en)
|
2017-12-15 |
2025-09-02 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
US20200392562A1
(en)
|
2017-12-22 |
2020-12-17 |
Thermo Fisher Scientific Baltics Uab |
Polymerase chain reaction composition comprising amines
|
|
US12157760B2
(en)
|
2018-05-23 |
2024-12-03 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
US12522807B2
(en)
|
2018-07-09 |
2026-01-13 |
The Broad Institute, Inc. |
RNA programmable epigenetic RNA modifiers and uses thereof
|
|
WO2020092453A1
(fr)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Éditeurs de nucléobases comprenant geocas9 et utilisations associées
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
WO2020191233A1
(fr)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Procédés et compositions pour l'édition de séquences nucléotidiques
|
|
US12473543B2
(en)
|
2019-04-17 |
2025-11-18 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
CN110093410A
(zh)
*
|
2019-05-21 |
2019-08-06 |
通用生物系统(安徽)有限公司 |
一种dna测序反应试剂及其制备方法
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
CN111534500A
(zh)
*
|
2019-11-13 |
2020-08-14 |
深圳市真迈生物科技有限公司 |
改造的Klenow片段及应用
|
|
US12428658B2
(en)
|
2019-11-25 |
2025-09-30 |
The General Hospital Corporation |
Methods and compositions for enzymatic polymerization of N3′→P5′ phosphoramidate DNA
|
|
IL297761A
(en)
|
2020-05-08 |
2022-12-01 |
Broad Inst Inc |
Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence
|
|
CA3193099A1
(fr)
|
2020-09-24 |
2022-03-31 |
David R. Liu |
Arn guides d'edition primaire, leurs compositions et leurs methodes d'utilisation
|
|
WO2022074058A1
(fr)
|
2020-10-06 |
2022-04-14 |
Keygene N.V. |
Addition de séquence ciblée
|
|
EP4274894A2
(fr)
|
2021-01-11 |
2023-11-15 |
The Broad Institute, Inc. |
Variants d'éditeur primaire, constructions et procédés pour améliorer l'efficacité et la précision d'une édition primaire
|
|
IL309368A
(en)
*
|
2021-06-29 |
2024-02-01 |
Agilent Technologies Inc |
polymerase mutants and use with 3'-OH UNBLOCKED REVERSIBLE TERMINATORS
|
|
WO2023076898A1
(fr)
|
2021-10-25 |
2023-05-04 |
The Broad Institute, Inc. |
Procédés et compositions pour l'édition d'un génome à l'aide d'une édition primaire et d'une recombinase
|
|
WO2024039652A1
(fr)
|
2022-08-16 |
2024-02-22 |
Aldevron, L.L.C. |
Procédé acellulaire de production d'acide nucléique circulaire synthétique
|
|
EP4619515A1
(fr)
|
2022-11-17 |
2025-09-24 |
The Broad Institute, Inc. |
Distribution d'éditeur primaire par vaa
|
|
WO2024138087A2
(fr)
|
2022-12-23 |
2024-06-27 |
The Broad Institute, Inc. |
Procédés et compositions pour moduler des facteurs cellulaires pour augmenter les efficacités d'édition primaire
|
|
EP4652272A1
(fr)
|
2023-01-18 |
2025-11-26 |
The Broad Institute Inc. |
Lecture médiée par édition primaire de codons de terminaison prématurée (pert)
|
|
WO2025064678A2
(fr)
|
2023-09-20 |
2025-03-27 |
The Broad Institute, Inc. |
Translecture médiée par édition primaire de mutations par décalage du cadre de lecture (perf)
|