IL114955A - N-substituted naphthofused lactams and pharmaceutical compositions containing them - Google Patents

N-substituted naphthofused lactams and pharmaceutical compositions containing them

Info

Publication number
IL114955A
IL114955A IL11495595A IL11495595A IL114955A IL 114955 A IL114955 A IL 114955A IL 11495595 A IL11495595 A IL 11495595A IL 11495595 A IL11495595 A IL 11495595A IL 114955 A IL114955 A IL 114955A
Authority
IL
Israel
Prior art keywords
naphthofused
lactams
substituted
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11495595A
Other languages
English (en)
Other versions
IL114955A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL114955A0 publication Critical patent/IL114955A0/xx
Publication of IL114955A publication Critical patent/IL114955A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11495595A 1994-08-17 1995-08-16 N-substituted naphthofused lactams and pharmaceutical compositions containing them IL114955A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK95294 1994-08-17

Publications (2)

Publication Number Publication Date
IL114955A0 IL114955A0 (en) 1995-12-08
IL114955A true IL114955A (en) 1999-12-22

Family

ID=8099355

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11495595A IL114955A (en) 1994-08-17 1995-08-16 N-substituted naphthofused lactams and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US5817654A (cs)
EP (1) EP0777668A1 (cs)
JP (1) JPH10504293A (cs)
CN (1) CN1158127A (cs)
AU (1) AU697003B2 (cs)
BR (1) BR9508805A (cs)
CA (1) CA2196877A1 (cs)
CZ (1) CZ45897A3 (cs)
HU (1) HUT76645A (cs)
IL (1) IL114955A (cs)
MX (1) MX9701187A (cs)
NO (1) NO970684L (cs)
PL (1) PL318633A1 (cs)
TW (1) TW321640B (cs)
WO (1) WO1996005195A1 (cs)
ZA (1) ZA956869B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211174B1 (en) * 1997-10-31 2001-04-03 Merck & Co., Inc. Naphtho-fused lactams promote release of growth hormone
US6380184B1 (en) 1998-10-28 2002-04-30 Bristol-Myers Squibb Co. Benzoazepines and analogs thereof useful as growth hormone secretagogues
CA2362290A1 (en) 1999-02-18 2000-08-24 Kaken Pharmaceutical Co., Ltd. Novel amide derivatives as growth hormone secretagogues
US6525203B1 (en) 1999-03-12 2003-02-25 Bristol-Myers Squibb Company Heterocyclic aromatic compounds useful as growth hormone secretagogues
US6518292B1 (en) 1999-03-12 2003-02-11 Bristol-Myers Squibb Co. Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
PL353335A1 (en) * 1999-06-30 2003-11-17 Hamilton Civic Hospitals Research Development, Inc. Heparin compositions that inhibit clot associated coagulation factors
CN1244561C (zh) 2000-05-11 2006-03-08 布里斯托尔-迈尔斯斯奎布公司 可用作生长激素促分泌素的四氢异喹啉类似物
HK1052315A1 (zh) * 2000-09-08 2003-09-11 Leo Pharma A/S 抗血栓形成合成物
AU2002357692A1 (en) 2001-11-09 2003-05-26 Bristol-Myers Squibb Company Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity
WO2013190520A2 (en) 2012-06-22 2013-12-27 The General Hospital Corporation Gh-releasing agents in the treatment of vascular stenosis and associated conditions
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions
CA3012832A1 (en) 2016-02-05 2017-08-10 Denali Therapeutics Inc. N-azepinyl-carboxamide inhibitors of receptor-interacting protein kinase1
RS63203B1 (sr) 2016-12-09 2022-06-30 Denali Therapeutics Inc Jedinjenja korisna kao inhibitori ripk1
EP4463229A1 (en) 2022-01-12 2024-11-20 Denali Therapeutics Inc. Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206235A (en) * 1991-03-20 1993-04-27 Merck & Co., Inc. Benzo-fused lactams that promote the release of growth hormone
US5583130A (en) * 1992-09-25 1996-12-10 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone

Also Published As

Publication number Publication date
IL114955A0 (en) 1995-12-08
MX9701187A (es) 1997-05-31
AU697003B2 (en) 1998-09-24
AU3161895A (en) 1996-03-07
CA2196877A1 (en) 1996-02-22
ZA956869B (en) 1996-04-10
TW321640B (cs) 1997-12-01
JPH10504293A (ja) 1998-04-28
US5817654A (en) 1998-10-06
CN1158127A (zh) 1997-08-27
BR9508805A (pt) 1998-01-06
NO970684L (no) 1997-04-17
EP0777668A1 (en) 1997-06-11
WO1996005195A1 (en) 1996-02-22
NO970684D0 (no) 1997-02-14
PL318633A1 (en) 1997-06-23
HUT76645A (en) 1997-10-28
CZ45897A3 (en) 1997-10-15

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Legal Events

Date Code Title Description
FF Patent granted