IL114049A - Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) containing active agent and non-aqueous vehicles for control or release of active agent from the gel - Google Patents

Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) containing active agent and non-aqueous vehicles for control or release of active agent from the gel

Info

Publication number
IL114049A
IL114049A IL11404995A IL11404995A IL114049A IL 114049 A IL114049 A IL 114049A IL 11404995 A IL11404995 A IL 11404995A IL 11404995 A IL11404995 A IL 11404995A IL 114049 A IL114049 A IL 114049A
Authority
IL
Israel
Prior art keywords
active agent
gel
acne
psoriasis
release
Prior art date
Application number
IL11404995A
Other languages
English (en)
Other versions
IL114049A0 (en
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Priority to IL12235995A priority Critical patent/IL122359A/xx
Priority to IL12235895A priority patent/IL122358A/xx
Publication of IL114049A0 publication Critical patent/IL114049A0/xx
Publication of IL114049A publication Critical patent/IL114049A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11404995A 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) containing active agent and non-aqueous vehicles for control or release of active agent from the gel IL114049A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL12235995A IL122359A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) comprising ethyl-6-[2-(4,4)-dimethylthiochroman-6-yl] nicotinate in a pharmaceutical carrier and a method for its preparation
IL12235895A IL122358A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne psoriasis) containing active agent and non-aqueous vehicles for control of solubility

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25509494A 1994-06-07 1994-06-07

Publications (2)

Publication Number Publication Date
IL114049A0 IL114049A0 (en) 1995-10-31
IL114049A true IL114049A (en) 2000-08-31

Family

ID=22966815

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12235995A IL122359A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) comprising ethyl-6-[2-(4,4)-dimethylthiochroman-6-yl] nicotinate in a pharmaceutical carrier and a method for its preparation
IL11404995A IL114049A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) containing active agent and non-aqueous vehicles for control or release of active agent from the gel
IL12235895A IL122358A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne psoriasis) containing active agent and non-aqueous vehicles for control of solubility

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL12235995A IL122359A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) comprising ethyl-6-[2-(4,4)-dimethylthiochroman-6-yl] nicotinate in a pharmaceutical carrier and a method for its preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL12235895A IL122358A (en) 1994-06-07 1995-06-07 Stable gel formulation for topical treatment of skin conditions (acne psoriasis) containing active agent and non-aqueous vehicles for control of solubility

Country Status (13)

Country Link
US (2) US5914334A (xx)
EP (2) EP1147778B1 (xx)
AT (2) ATE215836T1 (xx)
AU (1) AU693905B2 (xx)
CA (1) CA2191773C (xx)
DE (2) DE69535184T2 (xx)
DK (1) DK1147778T3 (xx)
ES (2) ES2269296T3 (xx)
IL (3) IL122359A (xx)
PT (1) PT1147778E (xx)
TW (1) TW379143B (xx)
WO (1) WO1995033489A1 (xx)
ZA (1) ZA954599B (xx)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA954599B (en) * 1994-06-07 1996-01-26 Allergan Inc Stable gel formulation for topical treatment of skin conditions
IT1288708B1 (it) * 1996-10-17 1998-09-23 Achille Sandoli Composizione farmaceutica comprendente trometamina per il trattamento per via topica dell'acne vulgaris.
JP4387463B2 (ja) * 1997-02-20 2009-12-16 アラーガン、インコーポレイテッド タザロテンおよびコルチコステロイドによる乾癬の処置
AU726141B2 (en) * 1997-06-11 2000-11-02 Allergan, Inc. Tazarotene and UVB phototherapy treatment for psoriasis
WO1999049841A1 (en) * 1998-03-30 1999-10-07 The Procter & Gamble Company Skin care compositions
US20020160995A1 (en) * 1998-08-03 2002-10-31 Easterling W. Jerry Medication and method for remediating existing scars through transdermal, topical delivery of calcium channel blockers
US20090098065A1 (en) * 2000-01-11 2009-04-16 Avikam Harel Composition and methods for the treatment of skin disorders
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
MX342305B (es) * 2000-04-26 2016-09-23 Watson Pharmaceuticals Inc * Minimizacion de experiencias adversas asociadas con la terapia con oxibutinina.
US7029694B2 (en) 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
FR2830449B1 (fr) * 2001-10-05 2004-04-23 Fabre Pierre Dermo Cosmetique Utilisation du tazarotene pour la preparation d'un vernis a ongles pour le traitement et/ou la prevention du psoriasis et un vernis a ongles le contenant
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
DK2020243T3 (en) * 2002-05-28 2018-11-19 Astrazeneca Ab Pharmaceutical composition which can be applied topically
US20040018220A1 (en) * 2002-07-26 2004-01-29 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
FR2848451B1 (fr) * 2002-12-17 2007-01-12 Galderma Res & Dev Procede de stabilisation chimique d'un retinoide solubilise et composition aqueuse obtenue selon le procede comprenant au moins un retinoide sous forme salifiee
BR0316892A (pt) * 2002-12-17 2005-10-25 Galderma Res & Dev Processo para a estabilização quìmica de um retinóide solubilizado, composição aquosa, uso de uma composição, uso cosmético de uma composição e uso de uma base
ZA200710371B (en) * 2005-05-10 2009-07-29 Dermipsor Ltd Compositions and methods for treating hyperproliferative epidermal diseases
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
US20070060620A1 (en) * 2005-09-09 2007-03-15 John Sefton Use of RAR retinoid agonists to increase sperm count and sperm mobility in males
JP2009510087A (ja) * 2005-09-30 2009-03-12 オーエムピー インコーポレーテッド 安定アスコルビン酸組成物
US20070178058A1 (en) * 2006-02-02 2007-08-02 Ramirez Jose E Methods of using stable ascorbic acid compositions
US20070269534A1 (en) * 2006-02-02 2007-11-22 Ramirez Jose E Methods of treating skin to enhance therapeutic treatment thereof
WO2007092312A2 (en) * 2006-02-03 2007-08-16 Stiefel Laboratories, Inc. Topical skin treating compositions
ES2582654T3 (es) 2006-03-31 2016-09-14 Stiefel Research Australia Pty Ltd Gel en suspensión espumable
MXPA06008988A (es) * 2006-08-08 2008-02-07 Fernando Ahumada Ayala Preparaciones topicas antiacne que contienen retinoide (tazaroteno o adapaleno), antibiotico (fosfato de clindamicina) y/o queratolitico (peroxido de bonzoilo en microesponjas).
US20080299182A1 (en) * 2007-03-01 2008-12-04 Shuyuan Zhang Methods and formulations for topical gene therapy
US9107815B2 (en) 2008-02-22 2015-08-18 Allergan, Inc. Sustained release poloxamer containing pharmaceutical compositions
US20110117182A1 (en) * 2009-07-30 2011-05-19 Allergan, Inc. Combination of dapsone with other anti-acne agents
HUE033144T2 (en) 2010-03-12 2017-11-28 Monsanto Technology Llc Agrochemical gel preparations
CA2811568A1 (en) * 2010-10-08 2012-04-12 Helperby Therapeutics Limited Novel composition
CA2929292C (en) 2013-10-31 2021-11-02 Sun Pharmaceutical Industries Limited Topical pharmaceutical composition of acitretin
EP3876935A4 (en) * 2018-11-08 2022-08-17 Varsona Therapeutics, Inc. TOPICAL FORMULATIONS OF 5-A REDUCTASE INHIBITORS AND THEIR USES
US11311556B2 (en) 2020-05-13 2022-04-26 Varsona Therapeutics, Inc. Topical dutasteride emulsions for treating endocrine therapy-induced alopecia
KR20230039979A (ko) * 2021-09-15 2023-03-22 서울대학교산학협력단 아토피 피부염 예방 또는 치료용 겔 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3934028A (en) * 1974-04-22 1976-01-20 The Regents Of The University Of California Acne and psoriasis treatment with retinoic acid analogs
US4895727A (en) * 1985-05-03 1990-01-23 Chemex Pharmaceuticals, Inc. Pharmaceutical vehicles for exhancing penetration and retention in the skin
US4810804A (en) * 1987-03-26 1989-03-07 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
DE69029804T2 (de) * 1989-06-07 1997-09-04 Gail S Bazzano VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL
AU670777B2 (en) * 1992-04-16 1996-08-01 Ortho Pharmaceutical Corporation Aqueous gel vehicles for retinoids
ZA954599B (en) * 1994-06-07 1996-01-26 Allergan Inc Stable gel formulation for topical treatment of skin conditions
AU726141B2 (en) * 1997-06-11 2000-11-02 Allergan, Inc. Tazarotene and UVB phototherapy treatment for psoriasis
US6017938A (en) * 1998-07-28 2000-01-25 Bershad; Susan Short contact treatment for acne
US6114348A (en) * 1999-03-10 2000-09-05 Weber; Paul J. Method of treating warts using tazarotene

Also Published As

Publication number Publication date
ES2269296T3 (es) 2007-04-01
IL122359A (en) 2001-08-26
US6258830B1 (en) 2001-07-10
DE69535184D1 (de) 2006-09-28
AU2821895A (en) 1996-01-04
EP1147778B1 (en) 2006-08-16
IL114049A0 (en) 1995-10-31
IL122358A (en) 2001-01-28
EP0764032B1 (en) 2002-04-10
CA2191773C (en) 2004-08-10
CA2191773A1 (en) 1995-12-14
DE69535184T2 (de) 2007-08-23
WO1995033489A1 (en) 1995-12-14
DE69526344D1 (de) 2002-05-16
EP0764032A1 (en) 1997-03-26
ES2173958T3 (es) 2002-11-01
AU693905B2 (en) 1998-07-09
TW379143B (en) 2000-01-11
ATE336263T1 (de) 2006-09-15
DK1147778T3 (da) 2006-12-18
PT1147778E (pt) 2006-12-29
ZA954599B (en) 1996-01-26
EP1147778A1 (en) 2001-10-24
DE69526344T2 (de) 2002-11-07
ATE215836T1 (de) 2002-04-15
US5914334A (en) 1999-06-22

Similar Documents

Publication Publication Date Title
IL114049A (en) Stable gel formulation for topical treatment of skin conditions (acne, psoriasis) containing active agent and non-aqueous vehicles for control or release of active agent from the gel
IN1997DE00284A (xx)
WO1996012498A3 (en) Dermatological compositions containing benzoyl peroxide and a compound reducing skin irritation
CA2262870A1 (en) Liposome-based topical vitamin d formulation
NZ503340A (en) Treatment for hairy hoof warts (papiliomatous digital dermatitis, or PDD)
PT1238660E (pt) Distribuicao sustentada de um agente activo utilizando um sistema implantavel
AU3685893A (en) Aqueous gel vehicles for retinoids
WO2003005979A3 (de) Osmolyte enhaltende kosmetische und dermatologische zubereitungen zur behandlung und aktiven prävention trockener haut und anderer negativer veränderungen der physiologischen homöostase der gesunden haut
FR2782269B1 (fr) Composition cosmetique et/ou dermatologique contenant de l'acide salicylique ou un derive d'acide salicylique et son utilisation
IL94490A0 (en) Stable,cosmetically acceptable topical gel formulation and method of treatment for acne
AU3202595A (en) 1,2-substituted imidazolyl compounds for the treatment of inflammation
ZA89233B (en) Topical metronidazole formulations and therapeutic uses thereof
WO1999008650A3 (en) Use of ascorbic acid in permanent waving and hair coloring compositions
CA2190505A1 (en) Use of gel formulations as dressing agents
AU674142B2 (en) Use of cosmetic composition
ES2164434T3 (es) Tratamiento topico de psoriasis que utiliza anticuerpos neutralizantes de il-8.
NZ506681A (en) Disinfecting composition
ES2137125A1 (es) La utilizacion de la sal de zinc del acido glicirretico en preparados contra el acne y las composiciones que contienen dicha sal.
IT1290781B1 (it) Agente attivo terapeutico per il trattamento di malattie degenerative neuronali.
ATE234071T1 (de) Gegen akne und entzündete comedonen wirksame wirkstoffkombinationen
CA2231118A1 (en) Pharmaceutical preparation containing nimesulide for topical use
AU2415099A (en) Active substance combination
CA2126704A1 (en) Dermatological Compositions and Methods for the Treatment of Skin Therewith
PT82685B (pt) Vectores de transformacao dos microrganismos de accao rizosferica favoravel a agricultura e estirpes transformadas e processo para a preparacao de um agente de accao rizosferica
EP0685230A4 (en) STABLE DERMATOLOGICAL PREPARATIONS CONTAINING MYCOHENOLIC ACID.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired