IL112557A - Peptides that are VIP antagonists and pharmaceutical compositions comprising them - Google Patents
Peptides that are VIP antagonists and pharmaceutical compositions comprising themInfo
- Publication number
- IL112557A IL112557A IL11255795A IL11255795A IL112557A IL 112557 A IL112557 A IL 112557A IL 11255795 A IL11255795 A IL 11255795A IL 11255795 A IL11255795 A IL 11255795A IL 112557 A IL112557 A IL 112557A
- Authority
- IL
- Israel
- Prior art keywords
- vip
- peptides
- pharmaceutical compositions
- relates
- vip antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/083—Neurotensin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/194,591 US5565424A (en) | 1994-02-07 | 1994-02-07 | Superactive VIP antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
IL112557A0 IL112557A0 (en) | 1995-05-26 |
IL112557A true IL112557A (en) | 2000-02-17 |
Family
ID=22718168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11255795A IL112557A (en) | 1994-02-07 | 1995-02-06 | Peptides that are VIP antagonists and pharmaceutical compositions comprising them |
Country Status (11)
Country | Link |
---|---|
US (1) | US5565424A (xx) |
EP (1) | EP0738280B1 (xx) |
JP (1) | JP3588119B2 (xx) |
AT (1) | ATE199160T1 (xx) |
AU (1) | AU697829B2 (xx) |
CA (1) | CA2182795C (xx) |
DE (1) | DE69520092T2 (xx) |
DK (1) | DK0738280T3 (xx) |
ES (1) | ES2155886T3 (xx) |
IL (1) | IL112557A (xx) |
WO (1) | WO1995021194A1 (xx) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849261A (en) * | 1991-02-08 | 1998-12-15 | Diatide, Inc. | Radiolabeled vasoactive intestinal peptides for diagnosis and therapy |
US6156725A (en) * | 1996-08-16 | 2000-12-05 | National Institute Of Immunology | Drug for the treatment of cancer |
US6492330B1 (en) * | 1996-08-16 | 2002-12-10 | National Institute Of Immunology | Antiangiogenic drugs |
EP0835662B1 (en) * | 1996-10-08 | 2001-11-14 | National Institute of Immunology | A drug for the treatment of cancer |
US20020099003A1 (en) * | 1997-10-28 | 2002-07-25 | Wilson Leland F. | Treatment of female sexual dysfunction with vasoactive agents, particularly vasoactive intestinal polypeptide and agonists thereof |
JP2003530297A (ja) * | 1998-10-16 | 2003-10-14 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ, リプリゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ | Vipアンタゴニストを用いる併用療法 |
CA2405714A1 (en) | 2000-02-18 | 2001-08-23 | Dabur Research Foundation | Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy |
EP1257576B1 (en) * | 2000-02-18 | 2004-09-15 | Dabur Research Foundation | Vasoactive intestinal peptide analogs |
US6828304B1 (en) | 2000-07-31 | 2004-12-07 | Dabur Research Foundation | Peptides for treatment of cancer |
WO2002010193A1 (en) * | 2000-07-31 | 2002-02-07 | Dabur Research Foundation | Lipid-peptide conjugates for treatment of cancer |
US20060075968A1 (en) * | 2004-10-12 | 2006-04-13 | Applied Materials, Inc. | Leak detector and process gas monitor |
CA2825333C (en) | 2011-02-02 | 2019-07-02 | Emory University | Antagonism of the vip signaling pathway |
US9458217B2 (en) * | 2013-12-05 | 2016-10-04 | Emory University | Methods of managing graft versus host disease |
US11859208B2 (en) | 2016-04-08 | 2024-01-02 | Emory University | Methods of treating cancer using cell based therapies |
US11850263B2 (en) | 2017-11-10 | 2023-12-26 | Emory University | Nanoparticles conjugated with vasoactive intestinal peptide antagonists |
WO2019209952A2 (en) | 2018-04-23 | 2019-10-31 | Emory University | Vip antagonists and uses in treating cancer |
JP2022507688A (ja) * | 2018-11-15 | 2022-01-18 | エモリー ユニバーシティー | 血管作用性小腸ペプチド(vip)アンタゴニストの組成物及び用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4605641A (en) * | 1984-10-09 | 1986-08-12 | Hoffmann-La Roche Inc. | Synthetic vasoactive intestinal peptide analogs |
US4734400A (en) * | 1984-10-09 | 1988-03-29 | Hoffmann-La Roche Inc. | Synthetic vasoactive intestinal peptide analogs |
US5196315A (en) * | 1990-05-01 | 1993-03-23 | The Johns Hopkins University | Human neuronal cell line |
DK0463450T3 (da) * | 1990-06-26 | 1994-06-27 | Sanwa Kagaku Kenkyusho Co | Vasoaktive intestinale polypeptid-analoger og udnyttelsen heraf |
US5217953A (en) * | 1990-11-30 | 1993-06-08 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Vasoactive intestinal peptide antagonist |
US5273963A (en) * | 1991-03-29 | 1993-12-28 | The George Washington University | Compositions and methods for treating small cell and nonsmall cell lung cancers |
IL99924A (en) * | 1991-10-31 | 1995-12-31 | Yeda Res & Dev | Derivatives of structurally modified vip and pharmaceutical compositions containing them |
-
1994
- 1994-02-07 US US08/194,591 patent/US5565424A/en not_active Expired - Lifetime
-
1995
- 1995-02-06 DK DK95909489T patent/DK0738280T3/da active
- 1995-02-06 EP EP95909489A patent/EP0738280B1/en not_active Expired - Lifetime
- 1995-02-06 WO PCT/US1995/001496 patent/WO1995021194A1/en active IP Right Grant
- 1995-02-06 ES ES95909489T patent/ES2155886T3/es not_active Expired - Lifetime
- 1995-02-06 CA CA002182795A patent/CA2182795C/en not_active Expired - Fee Related
- 1995-02-06 DE DE69520092T patent/DE69520092T2/de not_active Expired - Fee Related
- 1995-02-06 JP JP52080495A patent/JP3588119B2/ja not_active Expired - Fee Related
- 1995-02-06 AU AU17438/95A patent/AU697829B2/en not_active Ceased
- 1995-02-06 IL IL11255795A patent/IL112557A/xx not_active IP Right Cessation
- 1995-02-06 AT AT95909489T patent/ATE199160T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK0738280T3 (da) | 2001-09-17 |
CA2182795A1 (en) | 1995-08-10 |
ES2155886T3 (es) | 2001-06-01 |
AU1743895A (en) | 1995-08-21 |
JPH09511494A (ja) | 1997-11-18 |
DE69520092T2 (de) | 2001-08-02 |
CA2182795C (en) | 2007-11-06 |
EP0738280B1 (en) | 2001-02-14 |
JP3588119B2 (ja) | 2004-11-10 |
ATE199160T1 (de) | 2001-02-15 |
WO1995021194A1 (en) | 1995-08-10 |
IL112557A0 (en) | 1995-05-26 |
DE69520092D1 (de) | 2001-03-22 |
AU697829B2 (en) | 1998-10-15 |
EP0738280A1 (en) | 1996-10-23 |
US5565424A (en) | 1996-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |