WO2002010193A1 - Lipid-peptide conjugates for treatment of cancer - Google Patents
Lipid-peptide conjugates for treatment of cancer Download PDFInfo
- Publication number
- WO2002010193A1 WO2002010193A1 PCT/US2000/020876 US0020876W WO0210193A1 WO 2002010193 A1 WO2002010193 A1 WO 2002010193A1 US 0020876 W US0020876 W US 0020876W WO 0210193 A1 WO0210193 A1 WO 0210193A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- peptide
- leu
- tyr
- pro
- met
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2000265054A AU2000265054A1 (en) | 2000-07-31 | 2000-07-31 | Lipid-peptide conjugates for treatment of cancer |
EP00952334A EP1409519A1 (en) | 2000-07-31 | 2000-07-31 | Lipid-peptide conjugates for treatment of cancer |
PCT/US2000/020876 WO2002010193A1 (en) | 2000-07-31 | 2000-07-31 | Lipid-peptide conjugates for treatment of cancer |
CA002405728A CA2405728A1 (en) | 2000-07-31 | 2000-07-31 | Lipid-peptide conjugates for treatment of cancer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2000/020876 WO2002010193A1 (en) | 2000-07-31 | 2000-07-31 | Lipid-peptide conjugates for treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002010193A1 true WO2002010193A1 (en) | 2002-02-07 |
Family
ID=21741642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/020876 WO2002010193A1 (en) | 2000-07-31 | 2000-07-31 | Lipid-peptide conjugates for treatment of cancer |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1409519A1 (en) |
AU (1) | AU2000265054A1 (en) |
CA (1) | CA2405728A1 (en) |
WO (1) | WO2002010193A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1633380A2 (en) * | 2003-06-19 | 2006-03-15 | Yeda Research & Development Company, Ltd. | Antimicrobial and anticancer lipopeptides |
WO2017132728A1 (en) | 2016-02-01 | 2017-08-10 | University Of Canberra | Proteinaceous compounds and uses therefor |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0354992A2 (en) * | 1988-07-08 | 1990-02-21 | Yeda Research And Development Company Limited | Conjugates of VIP and active fragments thereof with hydrophobic moieties and topical compositions for use in the treatment of male impotence |
US5217953A (en) * | 1990-11-30 | 1993-06-08 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Vasoactive intestinal peptide antagonist |
US5565424A (en) * | 1994-02-07 | 1996-10-15 | Ramot - University Authority For Applied Research And Industrial Development Ltd. | Superactive VIP antagonists |
WO2000023096A2 (en) * | 1998-10-16 | 2000-04-27 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Combination therapy with vip antagonist |
-
2000
- 2000-07-31 EP EP00952334A patent/EP1409519A1/en not_active Withdrawn
- 2000-07-31 CA CA002405728A patent/CA2405728A1/en not_active Abandoned
- 2000-07-31 WO PCT/US2000/020876 patent/WO2002010193A1/en active Application Filing
- 2000-07-31 AU AU2000265054A patent/AU2000265054A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0354992A2 (en) * | 1988-07-08 | 1990-02-21 | Yeda Research And Development Company Limited | Conjugates of VIP and active fragments thereof with hydrophobic moieties and topical compositions for use in the treatment of male impotence |
US5217953A (en) * | 1990-11-30 | 1993-06-08 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Vasoactive intestinal peptide antagonist |
US5565424A (en) * | 1994-02-07 | 1996-10-15 | Ramot - University Authority For Applied Research And Industrial Development Ltd. | Superactive VIP antagonists |
WO2000023096A2 (en) * | 1998-10-16 | 2000-04-27 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Combination therapy with vip antagonist |
Non-Patent Citations (1)
Title |
---|
See also references of EP1409519A1 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1633380A2 (en) * | 2003-06-19 | 2006-03-15 | Yeda Research & Development Company, Ltd. | Antimicrobial and anticancer lipopeptides |
EP1633380A4 (en) * | 2003-06-19 | 2010-08-11 | Yeda Res & Dev | Antimicrobial and anticancer lipopeptides |
US8445636B2 (en) | 2003-06-19 | 2013-05-21 | Yeda Research & Development Co. Ltd. | Antimicrobial and anticancer lipopeptides |
WO2017132728A1 (en) | 2016-02-01 | 2017-08-10 | University Of Canberra | Proteinaceous compounds and uses therefor |
JP2019506167A (en) * | 2016-02-01 | 2019-03-07 | ユニバーシティ・オブ・キャンベラUniversity of Canberra | Proteinaceous compounds and their use |
JP7341451B2 (en) | 2016-02-01 | 2023-09-11 | エピアクシス セラピューティクス プロプライアタリー リミティド | Proteinaceous compounds and their uses |
Also Published As
Publication number | Publication date |
---|---|
AU2000265054A1 (en) | 2002-02-13 |
EP1409519A1 (en) | 2004-04-21 |
CA2405728A1 (en) | 2002-02-07 |
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