IL112515A - Pharmaceutical composition containing N,N-dimethyl-1-¬1-(4-chlorophenyl)cyclobutyl¾-3-methylbutylamine for use in the treatment of non-insulin dependent diabetes mellitus - Google Patents

Pharmaceutical composition containing N,N-dimethyl-1-¬1-(4-chlorophenyl)cyclobutyl¾-3-methylbutylamine for use in the treatment of non-insulin dependent diabetes mellitus

Info

Publication number
IL112515A
IL112515A IL11251595A IL11251595A IL112515A IL 112515 A IL112515 A IL 112515A IL 11251595 A IL11251595 A IL 11251595A IL 11251595 A IL11251595 A IL 11251595A IL 112515 A IL112515 A IL 112515A
Authority
IL
Israel
Prior art keywords
chlorophenyl
dimethyl
diabetes mellitus
methylbutylamine
dependent diabetes
Prior art date
Application number
IL11251595A
Other languages
English (en)
Other versions
IL112515A0 (en
Original Assignee
Boots Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22703362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL112515(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boots Pharma Inc filed Critical Boots Pharma Inc
Publication of IL112515A0 publication Critical patent/IL112515A0/xx
Publication of IL112515A publication Critical patent/IL112515A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Lubricants (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL11251595A 1994-02-03 1995-02-01 Pharmaceutical composition containing N,N-dimethyl-1-¬1-(4-chlorophenyl)cyclobutyl¾-3-methylbutylamine for use in the treatment of non-insulin dependent diabetes mellitus IL112515A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/190,924 US5459164A (en) 1994-02-03 1994-02-03 Medical treatment

Publications (2)

Publication Number Publication Date
IL112515A0 IL112515A0 (en) 1995-12-08
IL112515A true IL112515A (en) 2000-07-26

Family

ID=22703362

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11251595A IL112515A (en) 1994-02-03 1995-02-01 Pharmaceutical composition containing N,N-dimethyl-1-¬1-(4-chlorophenyl)cyclobutyl¾-3-methylbutylamine for use in the treatment of non-insulin dependent diabetes mellitus

Country Status (17)

Country Link
US (2) US5459164A (cs)
EP (1) EP0814788B1 (cs)
JP (1) JPH10503166A (cs)
KR (1) KR100339874B1 (cs)
CN (1) CN1070698C (cs)
AT (1) ATE205390T1 (cs)
AU (1) AU694761B2 (cs)
CA (1) CA2182620C (cs)
DE (1) DE69522716T2 (cs)
DK (1) DK0814788T3 (cs)
ES (1) ES2166817T3 (cs)
IL (1) IL112515A (cs)
PH (1) PH31220A (cs)
PT (1) PT814788E (cs)
TW (1) TW314466B (cs)
WO (1) WO1995020949A1 (cs)
ZA (1) ZA95814B (cs)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9619757D0 (en) * 1996-09-21 1996-11-06 Knoll Ag Chemical process
GB9619961D0 (en) * 1996-09-25 1996-11-13 Knoll Ag Medical treatment
GB9619962D0 (en) * 1996-09-25 1996-11-13 Knoll Ag Medical treatment
GB9727131D0 (en) 1997-12-24 1998-02-25 Knoll Ag Therapeutic agents
US6476078B2 (en) * 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6974838B2 (en) * 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6331571B1 (en) 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6323242B1 (en) 1998-12-02 2001-11-27 Peter Sterling Mueller Treatment of disorders secondary to organic impairments
US6696495B2 (en) * 1998-12-02 2004-02-24 Snowden Pharmaceuticals, Llc Treatment of disorders secondary to organic impairments
BG65170B1 (bg) * 1999-03-17 2007-05-31 Knoll Gmbh Използване на n-заместени производни на 1-[1-(4-хлорофенил)циклобутил]-3-метилбутиламин за производство на лекарство за лечение на разстройства при храненето
CZ20013284A3 (cs) * 1999-03-19 2002-10-16 Knoll Gmbh Farmaceutická kompozice pro léčbu osteoartritidy nebo dny
AU3896900A (en) * 1999-03-19 2000-10-09 Knoll Pharmaceutical Company Treatment of pain
CA2367022A1 (en) 1999-03-19 2000-09-28 Knoll Pharmaceutical Company Method of treating sleep apnoea
US6803387B1 (en) * 1999-03-19 2004-10-12 Abbott Gmbh & Co. Kg Treatment of neuropathic pain or fibromyalgia
EP1162965A1 (en) * 1999-03-19 2001-12-19 Knoll Pharmaceutical Company Method of controlling weight gain associated with therapeutic drugs
CA2367045A1 (en) * 1999-03-19 2000-09-28 Carl M. Mendel Treatment of certain cancers associated with weight gain
WO2000056320A1 (en) * 1999-03-19 2000-09-28 Knoll Pharmaceutical Company Treatment of menstrual function
US6552087B1 (en) 1999-03-19 2003-04-22 Abbott Gmbh & Co. Kg Therapeutic agent comprising (+)-sibutramine
US6376554B1 (en) 1999-03-19 2002-04-23 Knoll Pharmaceutical Company Method of treating sexual dysfunction
AU3895400A (en) 1999-03-19 2000-10-09 Knoll Pharmaceutical Company Control of metabolism
JP2002539250A (ja) * 1999-03-19 2002-11-19 クノール・ゲー・エム・ベー・ハー 肺高血圧症の治療
WO2000056308A1 (en) * 1999-03-19 2000-09-28 Knoll Pharmaceutical Company Prevention of cardiovascular disease
US6365632B1 (en) 1999-03-19 2002-04-02 Knoll Pharmaceuticals Company Treatment of orthostatic hypotension
WO2000056310A1 (en) * 1999-03-19 2000-09-28 Knoll Pharmaceutical Company Treatment of chronic fatigue syndrome
WO2000056321A1 (en) 1999-03-19 2000-09-28 Knoll Pharmaceutical Company Treatment of hyperactivity disorders
EP1165060A4 (en) * 1999-03-19 2002-06-12 Knoll Gmbh PROCESSING OF BILARIAL CALCULATIONS
GB9914744D0 (en) * 1999-06-24 1999-08-25 Knoll Ag Therapeutic agents
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
GB9926251D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Pharmaceutical formulation
US6232347B1 (en) 2000-03-17 2001-05-15 Knoll Pharmaceutical Company Treatment of osteoarthritis
US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US20040034101A1 (en) * 2001-11-05 2004-02-19 Cypress Bioscience, Inc. Treatment and prevention of depression secondary to pain (DSP)
US6602911B2 (en) 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
EP1545484A4 (en) * 2002-10-05 2010-01-13 Hanmi Pharm Ind Co Ltd PHARMACEUTICAL COMPOSITION WITH CRYSTALLINE SIBUTRAMINE METHANSULFONATE HEMIHYDRATE
US20050131074A1 (en) * 2003-08-04 2005-06-16 Beckman Kristen M. Methods for treating metabolic syndrome
EP1846359A4 (en) 2005-01-06 2010-03-31 Cj Cheiljedang Corp INORGANIC ACID SALTS OF SIBUTRAMINE
KR100627687B1 (ko) * 2005-04-20 2006-09-25 주식회사 씨티씨바이오 시부트라민 유리염기 함유 조성물 및 이의 제조방법
US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
AU2007322477A1 (en) * 2006-11-22 2008-05-29 Sk Chemicals Co., Ltd. Inclusion complex of sibutramine and beta-cyclodextrin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
GB8531071D0 (en) * 1985-12-17 1986-01-29 Boots Co Plc Therapeutic compound
GB8704777D0 (en) * 1987-02-28 1987-04-01 Boots Co Plc Medical treatment
PH23901A (en) * 1987-05-04 1989-12-18 Lilly Co Eli Treatment of diabetes using fluoxetine
JP2675573B2 (ja) * 1988-03-31 1997-11-12 科研製薬株式会社 脳機能改善剤
IE61928B1 (en) * 1988-11-29 1994-11-30 Boots Co Plc Treatment of obesity

Also Published As

Publication number Publication date
DE69522716T2 (de) 2002-05-29
IL112515A0 (en) 1995-12-08
ES2166817T3 (es) 2002-05-01
DK0814788T3 (da) 2001-11-19
KR100339874B1 (ko) 2002-11-22
CN1144479A (zh) 1997-03-05
AU694761B2 (en) 1998-07-30
PT814788E (pt) 2002-03-28
ATE205390T1 (de) 2001-09-15
DE69522716D1 (de) 2001-10-18
EP0814788A1 (en) 1998-01-07
CN1070698C (zh) 2001-09-12
TW314466B (cs) 1997-09-01
AU1736295A (en) 1995-08-21
US5942549A (en) 1999-08-24
WO1995020949A1 (en) 1995-08-10
EP0814788A4 (en) 1999-05-06
PH31220A (en) 1998-05-05
CA2182620C (en) 2007-01-16
JPH10503166A (ja) 1998-03-24
ZA95814B (en) 1995-08-03
EP0814788B1 (en) 2001-09-12
CA2182620A1 (en) 1995-08-10
US5459164A (en) 1995-10-17

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed