IL111989A - 3-substituted 1-arylindole compounds and pharmaceutical compositions containing them - Google Patents
3-substituted 1-arylindole compounds and pharmaceutical compositions containing themInfo
- Publication number
- IL111989A IL111989A IL11198994A IL11198994A IL111989A IL 111989 A IL111989 A IL 111989A IL 11198994 A IL11198994 A IL 11198994A IL 11198994 A IL11198994 A IL 11198994A IL 111989 A IL111989 A IL 111989A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- hydrogen
- group
- alkenyl
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polyesters Or Polycarbonates (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK931395A DK139593D0 (da) | 1993-12-16 | 1993-12-16 | Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IL111989A0 IL111989A0 (en) | 1995-03-15 |
IL111989A true IL111989A (en) | 2000-10-31 |
Family
ID=8104386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11198994A IL111989A (en) | 1993-12-16 | 1994-12-15 | 3-substituted 1-arylindole compounds and pharmaceutical compositions containing them |
Country Status (25)
Country | Link |
---|---|
US (1) | US5789404A (zh) |
EP (2) | EP0734384B1 (zh) |
JP (1) | JPH09506595A (zh) |
KR (1) | KR100363484B1 (zh) |
CN (1) | CN1080261C (zh) |
AT (1) | ATE195313T1 (zh) |
AU (1) | AU682915B2 (zh) |
CA (1) | CA2179179A1 (zh) |
CZ (1) | CZ285028B6 (zh) |
DE (1) | DE69425510T2 (zh) |
DK (2) | DK139593D0 (zh) |
ES (1) | ES2149959T3 (zh) |
FI (1) | FI962496A0 (zh) |
GR (1) | GR3034744T3 (zh) |
HK (1) | HK1013815A1 (zh) |
HU (1) | HU223318B1 (zh) |
IL (1) | IL111989A (zh) |
NO (1) | NO306671B1 (zh) |
NZ (1) | NZ277483A (zh) |
PL (1) | PL181253B1 (zh) |
PT (1) | PT734384E (zh) |
RU (1) | RU2139287C1 (zh) |
SK (1) | SK283451B6 (zh) |
WO (1) | WO1995016684A1 (zh) |
ZA (1) | ZA949918B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965582A (en) * | 1994-08-03 | 1999-10-12 | Asta Medica Aktiengesellschaft | N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect |
MY125942A (en) * | 1999-09-07 | 2006-09-29 | Upjohn Co | Aminoalkoxy carbazoles for the treatment of cns diseases |
CA2651732C (en) | 2006-05-18 | 2014-10-14 | Mannkind Corporation | Intracellular kinase inhibitors |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1220628A (en) * | 1968-07-20 | 1971-01-27 | Pfizer Ltd | N-phenyl indole derivatives and pharmaceutical compositions thereof |
GB1237008A (en) * | 1968-12-18 | 1971-06-30 | Pfizer Ltd | Novel indoline derivatives |
DE1911893A1 (de) * | 1969-03-08 | 1970-09-24 | Thiemann Gmbh Chem Pharm Fabri | Verfahren zur Herstellung von N-(Halogen-aryl)-2-methyl-5-alkoxy-indol-3-essigsaeuren |
BE795457A (fr) * | 1972-02-16 | 1973-08-16 | Clin Midy | Amines indoliques, leur preparation et leur application en therapeutiques |
FR2242091A1 (en) * | 1973-09-04 | 1975-03-28 | Delalande Sa | 1-Phenyl-2-methyl-3-aminomethyl-5-methoxy indole derivs - with e.g. analgesic, antidepressive and anti-arrhythmic props |
US4558048A (en) * | 1984-04-06 | 1985-12-10 | Pfizer Inc. | Method of treating diarrhoea using indole compounds |
DE3430284A1 (de) * | 1984-08-17 | 1986-02-27 | Troponwerke GmbH & Co KG, 5000 Köln | Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung |
DK152090D0 (da) * | 1990-06-22 | 1990-06-22 | Lundbaek A S H | Piperidylsubstituerede indolderivater |
DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
DK36391D0 (da) * | 1991-03-01 | 1991-03-01 | Lundbeck & Co As H | Anvendelse af piperidylsubstituerede indolderivater til behandling af stofmisbrug |
FR2701026B1 (fr) * | 1993-02-02 | 1995-03-31 | Adir | Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
FR2705346B1 (fr) * | 1993-05-18 | 1995-08-11 | Union Pharma Scient Appl | Nouveaux dérivés de pipéridinyl thio indole, leurs procédés de préparation, compositions pharmaceutiques les contenant, utiles notamment comme antalgiques . |
US5504101A (en) * | 1994-05-06 | 1996-04-02 | Allelix Biopharmaceuticals, Inc. | 5-HT-1D receptor ligands |
-
1993
- 1993-12-16 DK DK931395A patent/DK139593D0/da not_active Application Discontinuation
-
1994
- 1994-12-13 ZA ZA949918A patent/ZA949918B/xx unknown
- 1994-12-15 AT AT95903771T patent/ATE195313T1/de not_active IP Right Cessation
- 1994-12-15 KR KR1019960703199A patent/KR100363484B1/ko not_active IP Right Cessation
- 1994-12-15 PT PT95903771T patent/PT734384E/pt unknown
- 1994-12-15 DE DE69425510T patent/DE69425510T2/de not_active Expired - Fee Related
- 1994-12-15 JP JP7516476A patent/JPH09506595A/ja active Pending
- 1994-12-15 NZ NZ277483A patent/NZ277483A/en unknown
- 1994-12-15 CN CN94194964A patent/CN1080261C/zh not_active Expired - Fee Related
- 1994-12-15 ES ES95903771T patent/ES2149959T3/es not_active Expired - Lifetime
- 1994-12-15 CZ CZ961727A patent/CZ285028B6/cs not_active IP Right Cessation
- 1994-12-15 EP EP95903771A patent/EP0734384B1/en not_active Expired - Lifetime
- 1994-12-15 US US08/666,380 patent/US5789404A/en not_active Expired - Fee Related
- 1994-12-15 SK SK758-96A patent/SK283451B6/sk unknown
- 1994-12-15 WO PCT/DK1994/000470 patent/WO1995016684A1/en active IP Right Grant
- 1994-12-15 DK DK95903771T patent/DK0734384T3/da active
- 1994-12-15 AU AU12721/95A patent/AU682915B2/en not_active Ceased
- 1994-12-15 RU RU96115139/04A patent/RU2139287C1/ru not_active IP Right Cessation
- 1994-12-15 PL PL94315027A patent/PL181253B1/pl not_active IP Right Cessation
- 1994-12-15 CA CA002179179A patent/CA2179179A1/en not_active Abandoned
- 1994-12-15 IL IL11198994A patent/IL111989A/xx not_active IP Right Cessation
- 1994-12-15 HU HU9601640A patent/HU223318B1/hu not_active IP Right Cessation
- 1994-12-15 EP EP99106459A patent/EP0939077A3/en not_active Withdrawn
-
1996
- 1996-06-13 NO NO962505A patent/NO306671B1/no unknown
- 1996-06-14 FI FI962496A patent/FI962496A0/fi unknown
-
1998
- 1998-12-23 HK HK98115080A patent/HK1013815A1/xx not_active IP Right Cessation
-
2000
- 2000-11-02 GR GR20000402432T patent/GR3034744T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |