IL110532A - תותב לקרנית תוך-משתית - Google Patents
תותב לקרנית תוך-משתיתInfo
- Publication number
- IL110532A IL110532A IL11053294A IL11053294A IL110532A IL 110532 A IL110532 A IL 110532A IL 11053294 A IL11053294 A IL 11053294A IL 11053294 A IL11053294 A IL 11053294A IL 110532 A IL110532 A IL 110532A
- Authority
- IL
- Israel
- Prior art keywords
- insert
- segment
- cornea
- segments
- arc
- Prior art date
Links
- 210000004087 cornea Anatomy 0.000 claims description 62
- 229920000642 polymer Polymers 0.000 claims description 44
- 238000002513 implantation Methods 0.000 claims description 16
- 238000012937 correction Methods 0.000 claims description 11
- -1 polytetrafluoroethylene Polymers 0.000 claims description 10
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 7
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 3
- 239000004593 Epoxy Substances 0.000 claims description 2
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 239000004743 Polypropylene Substances 0.000 claims description 2
- 125000003700 epoxy group Chemical group 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 229920002492 poly(sulfone) Polymers 0.000 claims description 2
- 229920001748 polybutylene Polymers 0.000 claims description 2
- 229920000515 polycarbonate Polymers 0.000 claims description 2
- 239000004417 polycarbonate Substances 0.000 claims description 2
- 229920000647 polyepoxide Polymers 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920000098 polyolefin Polymers 0.000 claims description 2
- 229920001155 polypropylene Polymers 0.000 claims description 2
- 208000014733 refractive error Diseases 0.000 claims description 2
- 238000012876 topography Methods 0.000 claims description 2
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- 210000001508 eye Anatomy 0.000 description 44
- 239000010410 layer Substances 0.000 description 24
- 238000003780 insertion Methods 0.000 description 17
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- 201000009310 astigmatism Diseases 0.000 description 11
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- 208000001491 myopia Diseases 0.000 description 7
- 230000004379 myopia Effects 0.000 description 7
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 5
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
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- 210000003683 corneal stroma Anatomy 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
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- 210000000981 epithelium Anatomy 0.000 description 3
- 229920002674 hyaluronan Polymers 0.000 description 3
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- 102000008186 Collagen Human genes 0.000 description 2
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 206010020675 Hypermetropia Diseases 0.000 description 2
- 241000446313 Lamella Species 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
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- 229920002125 Sokalan® Polymers 0.000 description 2
- 230000004308 accommodation Effects 0.000 description 2
- 239000003124 biologic agent Substances 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 210000005252 bulbus oculi Anatomy 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 210000003161 choroid Anatomy 0.000 description 2
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- 229920000669 heparin Polymers 0.000 description 2
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- 238000011065 in-situ storage Methods 0.000 description 2
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- 210000003786 sclera Anatomy 0.000 description 2
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- 210000004127 vitreous body Anatomy 0.000 description 2
- MNIQECRMTVGZBM-UHFFFAOYSA-N 3-(1-methylpyrrolidin-2-yl)pyridine;7h-purin-6-amine Chemical compound NC1=NC=NC2=C1NC=N2.CN1CCCC1C1=CC=CN=C1 MNIQECRMTVGZBM-UHFFFAOYSA-N 0.000 description 1
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- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 208000013521 Visual disease Diseases 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
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- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000004480 accommodation of the lens Effects 0.000 description 1
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
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- 230000003527 anti-angiogenesis Effects 0.000 description 1
- 230000003510 anti-fibrotic effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
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- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 210000002555 descemet membrane Anatomy 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- 239000000032 diagnostic agent Substances 0.000 description 1
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- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
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- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 229920002189 poly(glycerol 1-O-monomethacrylate) polymer Polymers 0.000 description 1
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- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
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- 239000002356 single layer Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical compound FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
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- 230000000472 traumatic effect Effects 0.000 description 1
- 208000029257 vision disease Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10143893A | 1993-08-02 | 1993-08-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL110532A0 IL110532A0 (en) | 1994-11-11 |
| IL110532A true IL110532A (he) | 1998-12-06 |
Family
ID=22284639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11053294A IL110532A (he) | 1993-08-02 | 1994-08-01 | תותב לקרנית תוך-משתית |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5824086A (he) |
| EP (1) | EP0712301A4 (he) |
| JP (2) | JPH09503930A (he) |
| BR (1) | BR9407215A (he) |
| CA (1) | CA2168347A1 (he) |
| IL (1) | IL110532A (he) |
| SG (2) | SG52643A1 (he) |
| WO (1) | WO1995003755A1 (he) |
Families Citing this family (124)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6197056B1 (en) * | 1992-07-15 | 2001-03-06 | Ras Holding Corp. | Segmented scleral band for treatment of presbyopia and other eye disorders |
| US6966927B1 (en) | 1992-08-07 | 2005-11-22 | Addition Technology, Inc. | Hybrid intrastromal corneal ring |
| US5944752A (en) * | 1992-09-03 | 1999-08-31 | Kera Vision, Inc. | Astigmatic correcting intrastromal corneal insert |
| JPH09503930A (ja) | 1993-08-02 | 1997-04-22 | ケラビジョン，インコーポレイテッド | セグメント状の予備形成された角膜実質内挿入物 |
| IL117335A (en) * | 1995-03-02 | 2001-08-08 | Keravision Inc | Corneal implant for changing refractive properties |
| JPH11507269A (ja) * | 1995-06-07 | 1999-06-29 | ケラビジョン，インコーポレイテッド | 基質内角膜半径方向挿入物および挿入方法 |
| US5919228A (en) * | 1995-06-27 | 1999-07-06 | Hennig; Juergen | Corneal insert |
| BR9708285A (pt) * | 1996-02-09 | 1999-08-03 | Keravision Inc | Inserção corneal intra-estromal segmentada para alterar as propriedades refrativas corneais e métodos da mesma |
| US6171336B1 (en) | 1996-03-26 | 2001-01-09 | Mark R. Sawusch | Method, implant, and apparatus for refractive keratoplasty |
| FR2754173B1 (fr) * | 1996-10-07 | 1998-12-24 | Corneal Ind | Dispositif de mise en tension de la capsule cristallinienne, susceptible d'etre charge en au moins un principe actif et de liberer ledit principe actif, et sa preparation |
| US5733334A (en) * | 1996-12-09 | 1998-03-31 | Microoptix | Method and apparatus for adjusting corneal curvature |
| US5855604A (en) * | 1996-12-09 | 1999-01-05 | Microoptix, Llc | Method and apparatus for adjusting corneal curvature using a solid filled corneal ring |
| FR2758079B1 (fr) * | 1997-01-08 | 1999-06-25 | Corneal Laboratoires | Implant intra-corneen |
| AU3881301A (en) * | 1997-10-08 | 2001-07-26 | Ras Holding Corporation | Segmented scleral band for treatment of presbyopia and other eye disorders |
| US6991650B2 (en) | 1997-10-08 | 2006-01-31 | Refocus Ocular, Inc. | Scleral expansion device having duck bill |
| IL130299A (he) * | 1997-10-08 | 2004-12-15 | Ras Holding Corp | רצועה סקלרלית מקטעית לטיפול בפרסביופיה והפרעות עיניים אחרות |
| US6007578A (en) * | 1997-10-08 | 1999-12-28 | Ras Holding Corp | Scleral prosthesis for treatment of presbyopia and other eye disorders |
| US6050999A (en) | 1997-12-18 | 2000-04-18 | Keravision, Inc. | Corneal implant introducer and method of use |
| US6428572B2 (en) * | 1998-01-12 | 2002-08-06 | Menicon Co., Ltd. | Intraocular ring |
| US6206919B1 (en) * | 1998-01-14 | 2001-03-27 | Joseph Y. Lee | Method and apparatus to correct refractive errors using adjustable corneal arcuate segments |
| WO2000007525A1 (en) * | 1998-08-05 | 2000-02-17 | Keravision, Inc. | Corneal implant with migration preventer |
| FR2784287B1 (fr) | 1998-10-13 | 2000-12-08 | Georges Baikoff | Segment d'expansion sclerale |
| US6626941B2 (en) | 1998-12-23 | 2003-09-30 | Anamed, Inc. | Corneal implant and method of manufacture |
| US6361560B1 (en) | 1998-12-23 | 2002-03-26 | Anamed, Inc. | Corneal implant and method of manufacture |
| US6102946A (en) * | 1998-12-23 | 2000-08-15 | Anamed, Inc. | Corneal implant and method of manufacture |
| FR2787991B1 (fr) * | 1998-12-31 | 2001-05-25 | Medicale De Prec S M P Sa Soc | Dispositif pour traiter la presbytie ou autre affection oculaire |
| US6554424B1 (en) | 1999-03-01 | 2003-04-29 | Boston Innovative Optices, Inc. | System and method for increasing the depth of focus of the human eye |
| US6183512B1 (en) | 1999-04-16 | 2001-02-06 | Edwards Lifesciences Corporation | Flexible annuloplasty system |
| US6543453B1 (en) * | 1999-05-06 | 2003-04-08 | Sciencevision L.L.C. | Methods of refractive correction of the eye |
| TW587934B (en) | 1999-06-07 | 2004-05-21 | Ronald A Schachar | Improved scleral prosthesis for the treatment of presbyopia and other eye disorders |
| US7008396B1 (en) | 1999-09-03 | 2006-03-07 | Restorvision, Inc. | Ophthalmic device and method of manufacture and use |
| US6228113B1 (en) | 2000-01-10 | 2001-05-08 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Intracorneal astigmatic onlay |
| US20050119737A1 (en) * | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
| US8162927B2 (en) * | 2000-03-21 | 2012-04-24 | Gholam A. Peyman | Method and apparatus for accommodating intraocular lens |
| US20050113911A1 (en) * | 2002-10-17 | 2005-05-26 | Peyman Gholam A. | Adjustable intraocular lens for insertion into the capsular bag |
| US6436092B1 (en) * | 2000-03-21 | 2002-08-20 | Gholam A. Peyman | Adjustable universal implant blank for modifying corneal curvature and methods of modifying corneal curvature therewith |
| US6949093B1 (en) * | 2000-03-21 | 2005-09-27 | Minu, L.L.C. | Adjustable universal implant blank for modifying corneal curvature and methods of modifying corneal curvature therewith |
| US20070031473A1 (en) * | 2005-08-05 | 2007-02-08 | Peyman Gholam A | Drug delivery system and method |
| US7635388B1 (en) * | 2000-05-04 | 2009-12-22 | Tyler Thomas D | Device and method for incremental correction of sight disorders and occular diseases |
| WO2001087200A1 (en) | 2000-05-17 | 2001-11-22 | Addition Technology, Inc. | Multiple headed instrument for corneal surgery |
| US6511508B1 (en) | 2000-08-04 | 2003-01-28 | Environmental Robots, Inc. | Surgical correction of human eye refractive errors by active composite artificial muscle implants |
| US7060094B2 (en) | 2000-08-07 | 2006-06-13 | Ophthalmotronics, Inc. | Accommodating zonular mini-bridge implants |
| AU2001289038B2 (en) | 2000-09-12 | 2006-05-18 | Revision Optics, Inc. | System for packaging and handling an implant and method of use |
| US8668735B2 (en) | 2000-09-12 | 2014-03-11 | Revision Optics, Inc. | Corneal implant storage and delivery devices |
| US20050182489A1 (en) * | 2001-04-27 | 2005-08-18 | Peyman Gholam A. | Intraocular lens adapted for adjustment via laser after implantation |
| US20060241750A1 (en) * | 2001-05-22 | 2006-10-26 | Ras Holding Corp | Scleral expansion device having duck bill |
| US20040115271A1 (en) * | 2002-06-21 | 2004-06-17 | Alex Sacharoff | Hydration compositions for corneal pre-surgery treatment |
| FR2844703B1 (fr) * | 2002-09-25 | 2005-07-08 | Alain Nicolas Gilg | Dispositif intraoculaire pour restaurer l'accommodation de l'oeil atteint de presbytie |
| US7037335B2 (en) * | 2002-11-19 | 2006-05-02 | Eagle Vision, Inc. | Bulbous scleral implants for the treatment of eye disorders such as presbyopia and glaucoma |
| ATE421303T1 (de) * | 2003-05-20 | 2009-02-15 | Hermeking Heino Dr | Fixierring zur endo- oder extrakapsulären prothetischen rekonstruktion im vorderabschnittsbereich des menschlichen auges |
| US20040236343A1 (en) * | 2003-05-23 | 2004-11-25 | Taylor Jon B. | Insertion tool for ocular implant and method for using same |
| US7628810B2 (en) | 2003-05-28 | 2009-12-08 | Acufocus, Inc. | Mask configured to maintain nutrient transport without producing visible diffraction patterns |
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-
1994
- 1994-07-28 JP JP7505939A patent/JPH09503930A/ja not_active Withdrawn
- 1994-07-28 SG SG1996007276A patent/SG52643A1/en unknown
- 1994-07-28 BR BR9407215A patent/BR9407215A/pt not_active Application Discontinuation
- 1994-07-28 WO PCT/US1994/008462 patent/WO1995003755A1/en not_active Ceased
- 1994-07-28 SG SG200000639A patent/SG87083A1/en unknown
- 1994-07-28 EP EP94925120A patent/EP0712301A4/en not_active Ceased
- 1994-07-28 CA CA002168347A patent/CA2168347A1/en not_active Abandoned
- 1994-08-01 IL IL11053294A patent/IL110532A/he not_active IP Right Cessation
-
1996
- 1996-09-20 US US08/718,291 patent/US5824086A/en not_active Expired - Lifetime
-
1998
- 1998-10-19 US US09/174,808 patent/US6508837B1/en not_active Expired - Lifetime
-
2004
- 2004-06-28 JP JP2004190427A patent/JP2004283616A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH09503930A (ja) | 1997-04-22 |
| AU7515694A (en) | 1995-02-28 |
| US5824086A (en) | 1998-10-20 |
| EP0712301A4 (en) | 1996-12-11 |
| EP0712301A1 (en) | 1996-05-22 |
| US6508837B1 (en) | 2003-01-21 |
| AU687859B2 (en) | 1998-03-05 |
| JP2004283616A (ja) | 2004-10-14 |
| SG52643A1 (en) | 1998-09-28 |
| BR9407215A (pt) | 1996-09-17 |
| WO1995003755A1 (en) | 1995-02-09 |
| IL110532A0 (en) | 1994-11-11 |
| CA2168347A1 (en) | 1995-02-09 |
| SG87083A1 (en) | 2002-03-19 |
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