IL109517A - Pharmaceutical compositions containing zopolrestat or related compounds - Google Patents

Pharmaceutical compositions containing zopolrestat or related compounds

Info

Publication number
IL109517A
IL109517A IL10951794A IL10951794A IL109517A IL 109517 A IL109517 A IL 109517A IL 10951794 A IL10951794 A IL 10951794A IL 10951794 A IL10951794 A IL 10951794A IL 109517 A IL109517 A IL 109517A
Authority
IL
Israel
Prior art keywords
compound
dihydro
formula
ylmethyl
ylacetic acid
Prior art date
Application number
IL10951794A
Other languages
English (en)
Other versions
IL109517A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL109517A0 publication Critical patent/IL109517A0/xx
Publication of IL109517A publication Critical patent/IL109517A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10951794A 1993-05-10 1994-05-02 Pharmaceutical compositions containing zopolrestat or related compounds IL109517A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/059,688 US5391551A (en) 1993-05-10 1993-05-10 Method of lowering blood lipid levels

Publications (2)

Publication Number Publication Date
IL109517A0 IL109517A0 (en) 1994-08-26
IL109517A true IL109517A (en) 1998-08-16

Family

ID=22024600

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10951794A IL109517A (en) 1993-05-10 1994-05-02 Pharmaceutical compositions containing zopolrestat or related compounds

Country Status (10)

Country Link
US (1) US5391551A (zh)
EP (1) EP0624369A1 (zh)
JP (1) JP3153070B2 (zh)
KR (1) KR0140146B1 (zh)
CN (1) CN1047520C (zh)
AU (1) AU657444B2 (zh)
CA (1) CA2123059C (zh)
IL (1) IL109517A (zh)
TW (1) TW235919B (zh)
ZA (1) ZA943203B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834466A (en) * 1994-12-22 1998-11-10 The Regents Of The University Of California Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia
IL120264A0 (en) * 1996-02-29 1997-06-10 Pfizer Method of reducing tissue damage associated with non-cardiac ischemia
IL124236A (en) * 1997-05-05 2003-01-12 Pfizer Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor
UA57811C2 (uk) * 1997-11-21 2003-07-15 Пфайзер Продактс Інк. Фармацевтична композиція, що містить інгібітор альдозоредуктази та інгібітор глікогенфосфорилази (варіанти), комплект, який її включає, та способи лікування ссавців зі станом інсулінорезистентності
BR9909358A (pt) * 1998-03-31 2000-12-12 Inst For Pharm Discovery Inc Composto, composição farmacêutica, e, processo para prevenção ou alìvio de complicações crÈnicas decorrentes de diabetes melito
EP0982306A3 (en) * 1998-08-21 2000-07-05 Pfizer Products Inc. Polymorph of zopolrestat monohydrate
TNSN99224A1 (fr) 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
JP6244425B2 (ja) * 2016-08-18 2017-12-06 花王株式会社 Glp−1分泌促進剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492706A (en) * 1983-08-01 1985-01-08 American Home Products Corporation Method of lowering lipid levels
US4939140A (en) * 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
US4868301A (en) * 1987-06-09 1989-09-19 Pfizer Inc. Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
EP0310931A3 (en) * 1987-10-08 1990-10-03 Ethyl Corporation Poultry feed
EP0322153A3 (en) * 1987-12-21 1990-08-16 Pfizer Inc. Heterocyclic oxophtalazinyl acetic acids
US5064830A (en) * 1990-08-02 1991-11-12 Pfizer Inc. Lowering of blood uric acid levels

Also Published As

Publication number Publication date
CA2123059A1 (en) 1994-11-11
AU6196694A (en) 1994-12-01
EP0624369A1 (en) 1994-11-17
ZA943203B (en) 1995-11-09
JP3153070B2 (ja) 2001-04-03
AU657444B2 (en) 1995-03-09
CA2123059C (en) 1997-01-21
CN1103783A (zh) 1995-06-21
KR0140146B1 (ko) 1998-06-01
US5391551A (en) 1995-02-21
JPH08165241A (ja) 1996-06-25
IL109517A0 (en) 1994-08-26
TW235919B (zh) 1994-12-11
CN1047520C (zh) 1999-12-22

Similar Documents

Publication Publication Date Title
AU724327B2 (en) Method of reducing tissue damage associated with non-cardiac ischemia
HU220669B1 (hu) Eljárás diabéteszes szövődmények kezelésére vagy megelőzésére szolgáló gyógyászati készítmények előállítására
US5391551A (en) Method of lowering blood lipid levels
US5990111A (en) Aldose reductase inhibition in preventing or reversing diabetic cardiomyopathy
US5420135A (en) Substituted quinoline derivatives
AU604176B2 (en) Dl-5-{2-benzyl-3,4-dihydro-2h-benzopyran-6-yl}methyl} thiazolidine-2,4-dione as an anti-atherosclerosis agent
EP0132994B1 (en) Compounds for lowering lipid levels
EP0469837B1 (en) Use of a compound in the manufactur of a medicament for lowering of blood uric acid levels
JP3357378B2 (ja) 糖尿病処置用のオキシランカルボン酸
JPS62145068A (ja) 新規ヒダントイン誘導体及び該化合物を含有する脂質低下剤
GB2190587A (en) Compositions for treating arteriosclerosis
IE42948B1 (en) Pharmaceutically acceptable salts of alkanoic acid derivatives and compositions containing the same

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees