IL108173A - 2-amino-6,7- dihydroxy-4- thiaheptanoic acid derivatives, production and use thereof - Google Patents

2-amino-6,7- dihydroxy-4- thiaheptanoic acid derivatives, production and use thereof

Info

Publication number
IL108173A
IL108173A IL108173A IL10817393A IL108173A IL 108173 A IL108173 A IL 108173A IL 108173 A IL108173 A IL 108173A IL 10817393 A IL10817393 A IL 10817393A IL 108173 A IL108173 A IL 108173A
Authority
IL
Israel
Prior art keywords
amino
amino acid
dihydroxy
production
acid derivatives
Prior art date
Application number
IL108173A
Other languages
English (en)
Other versions
IL108173A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL108173A0 publication Critical patent/IL108173A0/xx
Publication of IL108173A publication Critical patent/IL108173A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IL108173A 1992-12-28 1993-12-24 2-amino-6,7- dihydroxy-4- thiaheptanoic acid derivatives, production and use thereof IL108173A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34906292 1992-12-28
JP5618593 1993-03-16
JP18173593 1993-07-22

Publications (2)

Publication Number Publication Date
IL108173A0 IL108173A0 (en) 1994-04-12
IL108173A true IL108173A (en) 1998-03-10

Family

ID=27295829

Family Applications (1)

Application Number Title Priority Date Filing Date
IL108173A IL108173A (en) 1992-12-28 1993-12-24 2-amino-6,7- dihydroxy-4- thiaheptanoic acid derivatives, production and use thereof

Country Status (15)

Country Link
US (1) US5478808A (zh)
EP (1) EP0604957B1 (zh)
KR (1) KR940014436A (zh)
CN (1) CN1094731A (zh)
AT (1) ATE170871T1 (zh)
AU (1) AU666789B2 (zh)
CA (1) CA2112523A1 (zh)
DE (1) DE69320931T2 (zh)
FI (1) FI935888A (zh)
HU (1) HUT65865A (zh)
IL (1) IL108173A (zh)
NO (1) NO934834L (zh)
NZ (1) NZ250588A (zh)
PH (1) PH30687A (zh)
TW (1) TW264479B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030046389A (ko) * 2000-09-01 2003-06-12 그리폰 테라퓨틱스, 인코포레이티드 친핵체에 안정한 티오에스테르 발생 화합물, 제조 및 사용방법
EP1382352A1 (de) * 2002-07-19 2004-01-21 GBF Gesellschaft für Biotechnologische Forschung mbH Bisacyloxypropylcystein-Konjugate und deren Verwendung
DE102005024040A1 (de) * 2005-05-25 2006-12-14 Rovi Gmbh & Co. Kosmetische Rohstoffe Kg Kosmetisches oder therapeutisches Kombinationspräparat mit Theanin
BRPI0611586A2 (pt) 2005-06-13 2010-09-21 Cleveland Biolabs Inc métodos de proteção contra apoptose mediante uso de lipopeptìdeos
CN101421293B (zh) 2006-03-01 2013-09-25 福冈县政府 含有肽脂质的载体和使用该载体将化合物引入细胞的方法
DE102009034779A1 (de) * 2009-07-25 2011-02-03 Emc Microcollections Gmbh Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen
EA031379B1 (ru) * 2010-03-23 2018-12-28 Новартис Аг Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000330B1 (de) * 1977-06-20 1981-08-05 Ciba-Geigy Ag Lipopeptide, Verfahren zu deren Herstellung und sie enthaltende pharmazeutische Präparate
EP0014815A3 (de) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen
EP0114787B1 (de) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Neue Peptidderivate
DE3546150A1 (de) * 1985-06-24 1987-01-22 Hoechst Ag Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung
JPH0446194A (ja) * 1990-06-13 1992-02-17 Fujisawa Pharmaceut Co Ltd Ｗｓ１２７９ａ物質、その生産法及び用途
JPH0499796A (ja) * 1990-08-13 1992-03-31 Kazuo Achinami 新規リポペプタイド及び抗腫瘍剤
DK0548024T3 (da) * 1991-12-19 1997-01-27 Ciba Geigy Ag Aminosulfonsyrederivater samt fremgangsmåder til deres fremstilling

Also Published As

Publication number Publication date
KR940014436A (ko) 1994-07-18
AU666789B2 (en) 1996-02-22
CN1094731A (zh) 1994-11-09
HU9303761D0 (en) 1994-04-28
EP0604957B1 (en) 1998-09-09
DE69320931D1 (de) 1998-10-15
PH30687A (en) 1997-09-16
NZ250588A (en) 1995-03-28
IL108173A0 (en) 1994-04-12
EP0604957A1 (en) 1994-07-06
NO934834L (no) 1994-06-29
AU5261493A (en) 1994-07-07
US5478808A (en) 1995-12-26
FI935888A0 (fi) 1993-12-27
DE69320931T2 (de) 1999-05-20
NO934834D0 (no) 1993-12-27
TW264479B (zh) 1995-12-01
CA2112523A1 (en) 1994-06-29
ATE170871T1 (de) 1998-09-15
HUT65865A (en) 1994-07-28
FI935888A (fi) 1994-06-29

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