IL107519A0 - Aryl-fused and hetaryl-fused-2,4-diazepines and 2,4-diazochines and pharmaceutical compositions containing them - Google Patents

Aryl-fused and hetaryl-fused-2,4-diazepines and 2,4-diazochines and pharmaceutical compositions containing them

Info

Publication number
IL107519A0
IL107519A0 IL10751993A IL10751993A IL107519A0 IL 107519 A0 IL107519 A0 IL 107519A0 IL 10751993 A IL10751993 A IL 10751993A IL 10751993 A IL10751993 A IL 10751993A IL 107519 A0 IL107519 A0 IL 107519A0
Authority
IL
Israel
Prior art keywords
aryl
fused
hetaryl
alkyl
aralkyl
Prior art date
Application number
IL10751993A
Other languages
English (en)
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of IL107519A0 publication Critical patent/IL107519A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL10751993A 1992-11-10 1993-11-05 Aryl-fused and hetaryl-fused-2,4-diazepines and 2,4-diazochines and pharmaceutical compositions containing them IL107519A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97439692A 1992-11-10 1992-11-10
US2192693A 1993-02-24 1993-02-24

Publications (1)

Publication Number Publication Date
IL107519A0 true IL107519A0 (en) 1994-02-27

Family

ID=26695257

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10751993A IL107519A0 (en) 1992-11-10 1993-11-05 Aryl-fused and hetaryl-fused-2,4-diazepines and 2,4-diazochines and pharmaceutical compositions containing them

Country Status (15)

Country Link
EP (1) EP0597540B1 (ja)
JP (1) JPH06220025A (ja)
AT (1) ATE138916T1 (ja)
AU (1) AU4472093A (ja)
CA (1) CA2104060A1 (ja)
CZ (1) CZ237393A3 (ja)
DE (1) DE69302991D1 (ja)
FI (1) FI934895A (ja)
HU (1) HUT67281A (ja)
IL (1) IL107519A0 (ja)
MX (1) MX9305312A (ja)
NO (1) NO934058D0 (ja)
NZ (1) NZ248414A (ja)
SK (1) SK124593A3 (ja)
TW (1) TW245714B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101296926A (zh) * 2005-10-27 2008-10-29 先灵公司 天冬氨酰蛋白酶抑制剂
EP2323991B1 (en) * 2008-08-13 2017-05-31 Boehringer Ingelheim International GmbH Chymase inhibitors
US20130116241A1 (en) * 2011-11-09 2013-05-09 Abbvie Inc. Novel inhibitor compounds of phosphodiesterase type 10a
KR101991429B1 (ko) * 2014-12-19 2019-06-20 주식회사 엘지화학 새로운 화합물 및 이를 이용한 고분자 전해질막
KR102588822B1 (ko) * 2019-05-29 2023-10-19 에스티팜 주식회사 프탈라진온 화합물 및 이들의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH527828A (de) * 1967-04-13 1972-09-15 Ciba Geigy Ag Verfahren zur Herstellung von 2,4-Benzdiazepinen
US3696093A (en) * 1970-09-30 1972-10-03 Ciba Geigy Corp 2,4-benzodiazepines
NZ232396A (en) * 1989-02-10 1991-07-26 Merrell Dow Pharma 2-(diphenylalkylamino) -1,3 nn heterocyclic compounds and pharmaceutical compositions
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
TW245719B (ja) * 1990-09-10 1995-04-21 Sterling Winthrop Inc

Also Published As

Publication number Publication date
JPH06220025A (ja) 1994-08-09
TW245714B (ja) 1995-04-21
ATE138916T1 (de) 1996-06-15
AU4472093A (en) 1994-05-26
FI934895A (fi) 1994-05-11
EP0597540A1 (en) 1994-05-18
HU9303135D0 (en) 1994-02-28
NO934058D0 (no) 1993-11-09
MX9305312A (es) 1995-01-31
EP0597540B1 (en) 1996-06-05
HUT67281A (en) 1995-03-28
CA2104060A1 (en) 1994-05-11
CZ237393A3 (en) 1996-08-14
NO934058L (ja) 1994-05-11
FI934895A0 (fi) 1993-11-05
DE69302991D1 (de) 1996-07-11
SK124593A3 (en) 1994-08-10
NZ248414A (en) 1995-02-24

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