IL106107A - Imidazolyl-substituted cyclohexane derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Imidazolyl-substituted cyclohexane derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL106107A
IL106107A IL106107A IL10610793A IL106107A IL 106107 A IL106107 A IL 106107A IL 106107 A IL106107 A IL 106107A IL 10610793 A IL10610793 A IL 10610793A IL 106107 A IL106107 A IL 106107A
Authority
IL
Israel
Prior art keywords
imidazolyl
cyclohexane derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL106107A
Other languages
English (en)
Other versions
IL106107A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL106107A0 publication Critical patent/IL106107A0/xx
Priority to IL12050097A priority Critical patent/IL120500A0/xx
Publication of IL106107A publication Critical patent/IL106107A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/39—Unsaturated compounds containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/75—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of acids with a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL106107A 1992-06-26 1993-06-23 Imidazolyl-substituted cyclohexane derivatives, their preparation and pharmaceutical compositions containing them IL106107A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL12050097A IL120500A0 (en) 1992-06-26 1997-03-20 Cyclohexane compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4221009A DE4221009A1 (de) 1992-06-26 1992-06-26 Imidazolyl-substituierte Cyclohexanderivate

Publications (2)

Publication Number Publication Date
IL106107A0 IL106107A0 (en) 1993-10-20
IL106107A true IL106107A (en) 1997-09-30

Family

ID=6461902

Family Applications (1)

Application Number Title Priority Date Filing Date
IL106107A IL106107A (en) 1992-06-26 1993-06-23 Imidazolyl-substituted cyclohexane derivatives, their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US5508299A (xx)
EP (1) EP0581003B1 (xx)
JP (1) JPH0673016A (xx)
KR (1) KR940000435A (xx)
CN (2) CN1037512C (xx)
AT (1) ATE196136T1 (xx)
AU (1) AU666732B2 (xx)
CA (1) CA2099078A1 (xx)
CZ (1) CZ282309B6 (xx)
DE (2) DE4221009A1 (xx)
ES (1) ES2151891T3 (xx)
FI (1) FI932952A (xx)
HU (1) HUT64753A (xx)
IL (1) IL106107A (xx)
MX (1) MX9303599A (xx)
NO (1) NO303825B1 (xx)
NZ (1) NZ247974A (xx)
PH (1) PH31425A (xx)
RU (1) RU2110514C1 (xx)
SK (1) SK281028B6 (xx)
TW (1) TW245713B (xx)
ZA (1) ZA934583B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW215434B (xx) * 1992-03-07 1993-11-01 Hoechst Ag
HRP960015B1 (en) * 1995-02-01 2000-12-31 Bayer Ag Substituted indole derivatives
US5844318A (en) 1997-02-18 1998-12-01 Micron Technology, Inc. Aluminum film for semiconductive devices
DE19924818A1 (de) 1999-05-29 2000-11-30 Bayer Ag Substituierte Phenylcyclohexancarbonsäureamide
AU2001267404A1 (en) * 2000-05-04 2001-11-12 Ipf Pharmaceuticals Gmbh Novel compounds for the treatment of inflammatory and cardiovascular diseases
US20240336638A1 (en) * 2021-07-01 2024-10-10 Guoqin ZHUGE Imidazole compound, and intermediate and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
SG50669A1 (en) * 1989-06-30 1998-07-20 Du Pont Fused-ring aryl subtituted imidazoles

Also Published As

Publication number Publication date
CN1182734A (zh) 1998-05-27
IL106107A0 (en) 1993-10-20
CZ282309B6 (cs) 1997-06-11
PH31425A (en) 1998-10-29
NO932133L (no) 1993-12-27
CA2099078A1 (en) 1993-12-27
FI932952A0 (fi) 1993-06-24
EP0581003A1 (de) 1994-02-02
CN1037512C (zh) 1998-02-25
AU666732B2 (en) 1996-02-22
NO303825B1 (no) 1998-09-07
RU2110514C1 (ru) 1998-05-10
AU4146393A (en) 1994-01-06
KR940000435A (ko) 1994-01-03
CZ117393A3 (en) 1994-01-19
NO932133D0 (no) 1993-06-10
SK66893A3 (en) 1994-02-02
DE59310098D1 (de) 2000-10-12
HU9301870D0 (en) 1993-09-28
SK281028B6 (sk) 2000-11-07
CN1082538A (zh) 1994-02-23
ZA934583B (en) 1994-02-02
FI932952A (fi) 1993-12-27
ATE196136T1 (de) 2000-09-15
MX9303599A (es) 1994-01-31
ES2151891T3 (es) 2001-01-16
HUT64753A (en) 1994-02-28
US5508299A (en) 1996-04-16
EP0581003B1 (de) 2000-09-06
JPH0673016A (ja) 1994-03-15
TW245713B (xx) 1995-04-21
DE4221009A1 (de) 1994-01-05
NZ247974A (en) 1996-07-26

Similar Documents

Publication Publication Date Title
CS782686A2 (en) Method of benzimidazole derivatives production
IL104006A (en) Azaheterocyclylmethyl-chromans their preparation and pharmaceutical compositions containing them
ATE494009T1 (de) Prodrugs, ihre herstellung und verwendung als arzneimittel
AU6194694A (en) Nor-bile acid derivatives, processes for their preparation and the use of these compounds as medicaments
IL109604A0 (en) Substituted mono- and bipyridylmethyl- pyridones, process for their preparation and pharmaceutical compositions containing them
EP0279149A3 (en) Benzimidazole derivatives, process for their production and a pharmaceutical composition containing the same
HU206701B (en) Process for producing substituted flavonoid derivatives and salts and pharmaceutical compositions containing these compounds
HUT70150A (en) Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines, pharmaceutical compositions containing them and method for its preparation
IL105646A0 (en) Sulfonylbenzyl-substituted benzo-and pyridopyridones,their preparation and pharmaceutical compositions containing them
HUT45983A (en) Process for production of derivatives of imidazolidinone
HUT46224A (en) Process for producing pharmaceutical compositions containing prostaglandin e1-derivatives
IL106107A (en) Imidazolyl-substituted cyclohexane derivatives, their preparation and pharmaceutical compositions containing them
IL104005A0 (en) Piperidylmethyl-substituted chroman derivatives,their preparation and pharmaceutical compositions containing them
IL108997A0 (en) Heterotricyclically substituted phenyl-cyclohexane-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
EP0590272A3 (en) 17-aryl and 17-heterocyclyl-5-beta, 14-beta-andostane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void