IL104818A - Preparation of intermediates in the synthesis of quinoline antibiotics and such novel intermediates - Google Patents
Preparation of intermediates in the synthesis of quinoline antibiotics and such novel intermediatesInfo
- Publication number
- IL104818A IL104818A IL104818A IL10481893A IL104818A IL 104818 A IL104818 A IL 104818A IL 104818 A IL104818 A IL 104818A IL 10481893 A IL10481893 A IL 10481893A IL 104818 A IL104818 A IL 104818A
- Authority
- IL
- Israel
- Prior art keywords
- intermediates
- synthesis
- preparation
- novel
- quinoline antibiotics
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 3
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- LOAUVZALPPNFOQ-UHFFFAOYSA-N quinaldic acid Chemical class C1=CC=CC2=NC(C(=O)O)=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/844,367 US5256791A (en) | 1992-03-02 | 1992-03-02 | Preparation of intermediates in the synthesis of quinoline antibiotics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL104818A0 IL104818A0 (en) | 1993-06-10 |
| IL104818A true IL104818A (en) | 1997-09-30 |
Family
ID=25292537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL104818A IL104818A (en) | 1992-03-02 | 1993-02-22 | Preparation of intermediates in the synthesis of quinoline antibiotics and such novel intermediates |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US5256791A (de) |
| EP (1) | EP0629189B1 (de) |
| JP (1) | JP2564247B2 (de) |
| KR (2) | KR950700251A (de) |
| CN (1) | CN1037100C (de) |
| AT (1) | ATE156480T1 (de) |
| AU (1) | AU667872B2 (de) |
| CA (1) | CA2131160C (de) |
| DE (1) | DE69312913T2 (de) |
| DK (1) | DK0629189T3 (de) |
| ES (1) | ES2105217T3 (de) |
| FI (1) | FI106022B (de) |
| GR (1) | GR3024789T3 (de) |
| HU (1) | HU215837B (de) |
| IL (1) | IL104818A (de) |
| MX (1) | MX9301138A (de) |
| MY (1) | MY107723A (de) |
| NO (1) | NO300681B1 (de) |
| NZ (1) | NZ246768A (de) |
| TW (1) | TW211002B (de) |
| WO (1) | WO1993018001A1 (de) |
| ZA (1) | ZA931428B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ286896B6 (en) | 1994-01-18 | 2000-07-12 | Pfizer | Process for preparing pharmaceutically acceptable salts of naphthyridone carboxylic acid and intermediates for this preparation |
| US5475116A (en) * | 1994-04-29 | 1995-12-12 | Pfizer Inc. | Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones |
| US5929240A (en) * | 1994-12-12 | 1999-07-27 | Pfizer Inc. | Process and intermediates for preparing naphthyridonecarboxylic acid salts |
| JPH0912547A (ja) * | 1995-06-23 | 1997-01-14 | Chisso Corp | ニューキノロン系化合物中間体の製造方法 |
| GB9524466D0 (en) * | 1995-11-30 | 1996-01-31 | Pfizer Ltd | Process |
| US6057455A (en) * | 1996-07-09 | 2000-05-02 | Pfizer, Inc. | Preparation of intermediates useful in the synthesis of quinoline antibiotics |
| JPH1087617A (ja) * | 1996-07-09 | 1998-04-07 | Pfizer Inc | キノリン系抗生物質の合成に有用な中間体の製法 |
| GB9614422D0 (en) * | 1996-07-09 | 1996-09-04 | Pfizer Ltd | Novel process |
| HN1998000106A (es) | 1997-08-01 | 1999-01-08 | Pfizer Prod Inc | Composiciones parenterales de alatroflaxacino |
| DE19733439A1 (de) * | 1997-08-02 | 1999-02-04 | Bayer Ag | Neue 6-endo-Amino-3-azabicyclo(3.1.0)hexande, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von Chinolon- und Naphthyridincarbonsäure-Derviaten mit verbesserten Eigenschaften |
| US6184380B1 (en) * | 1999-01-25 | 2001-02-06 | Pfizer Inc. | Process for preparing naphthyridones and intermediates |
| US7019142B2 (en) | 1998-01-16 | 2006-03-28 | Pfizer Inc. | Process for preparing naphthyridones and intermediates |
| PA8464701A1 (es) * | 1998-01-16 | 2000-09-29 | Pfizer Prod Inc | Procedimiento e intermedios para preparar naftiridonas |
| WO2008010061A2 (en) * | 2006-07-17 | 2008-01-24 | Glenmark Pharmaceuticals S.A. | 3-azabicyclo [3.1.0] hexane vanilloid receptor ligands, pharmaceutical compositions containing them, and processes for their preparation |
| CA3142351A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| CA3141826A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| WO2023151188A1 (zh) * | 2022-02-08 | 2023-08-17 | 上海皓元医药股份有限公司 | 一种抗病毒药物中间体的绿色合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4183857A (en) * | 1978-07-06 | 1980-01-15 | Shell Oil Company | 3-Benzyl-3-azabicyclo(3.1.0)hexane-2,4-dione |
| DE2962910D1 (en) * | 1978-10-27 | 1982-07-08 | Shell Int Research | A process for the preparation of 3-azabicyclo(3.1.0)hexane derivatives and modifications thereof |
| JPH0676400B2 (ja) * | 1987-08-25 | 1994-09-28 | 大日本製薬株式会社 | 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩 |
| US5196548A (en) * | 1989-05-11 | 1993-03-23 | Pfizer Inc. | Preparation of diazabicyclic Intermediates |
| WO1991002526A1 (en) * | 1989-08-16 | 1991-03-07 | Pfizer Inc. | Azabicyclo quinolone carboxylic acids |
| US5200527A (en) * | 1991-04-08 | 1993-04-06 | Lonza Ltd. | Process for the production of 2-azabicyclo [2.2.1] hept-5-en-3-one |
-
1992
- 1992-03-02 US US07/844,367 patent/US5256791A/en not_active Expired - Fee Related
-
1993
- 1993-01-07 KR KR1019940703051A patent/KR950700251A/ko active Granted
- 1993-01-07 JP JP5515648A patent/JP2564247B2/ja not_active Expired - Lifetime
- 1993-01-07 NZ NZ246768A patent/NZ246768A/en unknown
- 1993-01-07 EP EP93902893A patent/EP0629189B1/de not_active Expired - Lifetime
- 1993-01-07 KR KR1019940703051A patent/KR0135626B1/ko not_active Expired - Fee Related
- 1993-01-07 AT AT93902893T patent/ATE156480T1/de active
- 1993-01-07 DK DK93902893.2T patent/DK0629189T3/da active
- 1993-01-07 DE DE69312913T patent/DE69312913T2/de not_active Expired - Fee Related
- 1993-01-07 ES ES93902893T patent/ES2105217T3/es not_active Expired - Lifetime
- 1993-01-07 WO PCT/US1993/000008 patent/WO1993018001A1/en not_active Ceased
- 1993-01-07 AU AU34300/93A patent/AU667872B2/en not_active Ceased
- 1993-01-07 CA CA002131160A patent/CA2131160C/en not_active Expired - Fee Related
- 1993-01-07 HU HU9402530A patent/HU215837B/hu not_active IP Right Cessation
- 1993-01-11 TW TW082100123A patent/TW211002B/zh active
- 1993-02-22 IL IL104818A patent/IL104818A/xx not_active IP Right Cessation
- 1993-03-01 ZA ZA931428A patent/ZA931428B/xx unknown
- 1993-03-01 CN CN93102103A patent/CN1037100C/zh not_active Expired - Fee Related
- 1993-03-01 MX MX9301138A patent/MX9301138A/es not_active IP Right Cessation
- 1993-03-01 MY MYPI93000368A patent/MY107723A/en unknown
- 1993-08-04 US US08/101,879 patent/US5298629A/en not_active Expired - Fee Related
-
1994
- 1994-09-01 NO NO943243A patent/NO300681B1/no not_active IP Right Cessation
- 1994-09-01 FI FI944013A patent/FI106022B/fi active
-
1997
- 1997-09-17 GR GR970402413T patent/GR3024789T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |