IL103584A - Treatment of protozoan infection with bivalent salt of bicarcin - Google Patents
Treatment of protozoan infection with bivalent salt of bicarcinInfo
- Publication number
- IL103584A IL103584A IL10358492A IL10358492A IL103584A IL 103584 A IL103584 A IL 103584A IL 10358492 A IL10358492 A IL 10358492A IL 10358492 A IL10358492 A IL 10358492A IL 103584 A IL103584 A IL 103584A
- Authority
- IL
- Israel
- Prior art keywords
- bacitracin
- treatment
- infection
- compositions
- zinc
- Prior art date
Links
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- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 231100001256 chronic oral toxicity Toxicity 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
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- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000012737 fresh medium Substances 0.000 description 1
- 229940085435 giardia lamblia Drugs 0.000 description 1
- 239000003979 granulating agent Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 229940116364 hard fat Drugs 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 244000144980 herd Species 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 208000029080 human African trypanosomiasis Diseases 0.000 description 1
- 244000000011 human parasite Species 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 125000001165 hydrophobic group Chemical group 0.000 description 1
- 125000002883 imidazolyl group Chemical group 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229950000107 ipronidazole Drugs 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 231100000225 lethality Toxicity 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 210000004324 lymphatic system Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000019656 metallic taste Nutrition 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 244000005706 microflora Species 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
- 231100000243 mutagenic effect Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000036438 mutation frequency Effects 0.000 description 1
- 231100000376 mutation frequency increase Toxicity 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000002352 nonmutagenic effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 244000000042 obligate parasite Species 0.000 description 1
- ZHALDANPYXAMJF-UHFFFAOYSA-N octadecanoate;tris(2-hydroxyethyl)azanium Chemical compound OCC[NH+](CCO)CCO.CCCCCCCCCCCCCCCCCC([O-])=O ZHALDANPYXAMJF-UHFFFAOYSA-N 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 229940096978 oral tablet Drugs 0.000 description 1
- 231100000418 oral toxicity Toxicity 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
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- 230000036961 partial effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 208000033808 peripheral neuropathy Diseases 0.000 description 1
- 206010034674 peritonitis Diseases 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 230000007824 polyneuropathy Effects 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229940068965 polysorbates Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 244000000040 protozoan parasite Species 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 210000005000 reproductive tract Anatomy 0.000 description 1
- 230000005801 respiratory difficulty Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 210000004767 rumen Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000009291 secondary effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 201000002612 sleeping sickness Diseases 0.000 description 1
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
- NWZBFJYXRGSRGD-UHFFFAOYSA-M sodium;octadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOS([O-])(=O)=O NWZBFJYXRGSRGD-UHFFFAOYSA-M 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 229940100515 sorbitan Drugs 0.000 description 1
- 210000004989 spleen cell Anatomy 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 231100001044 testicular atrophy Toxicity 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 229940029614 triethanolamine stearate Drugs 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78566691A | 1991-10-31 | 1991-10-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL103584A0 IL103584A0 (en) | 1993-03-15 |
| IL103584A true IL103584A (en) | 1996-06-18 |
Family
ID=25136245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10358492A IL103584A (en) | 1991-10-31 | 1992-10-29 | Treatment of protozoan infection with bivalent salt of bicarcin |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5300491A (de) |
| EP (1) | EP0669831B1 (de) |
| JP (1) | JPH07500601A (de) |
| AT (1) | ATE190847T1 (de) |
| AU (1) | AU664721B2 (de) |
| CA (1) | CA2122598C (de) |
| CZ (1) | CZ105794A3 (de) |
| DE (1) | DE69230835T2 (de) |
| EE (1) | EE9400161A (de) |
| ES (1) | ES2147554T3 (de) |
| IL (1) | IL103584A (de) |
| LT (1) | LT3158B (de) |
| LV (1) | LV10392B (de) |
| NZ (1) | NZ244966A (de) |
| RU (1) | RU94021356A (de) |
| SK (1) | SK49794A3 (de) |
| WO (1) | WO1993008822A1 (de) |
| ZA (1) | ZA928421B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5620953A (en) * | 1994-07-27 | 1997-04-15 | Merck & Co., Inc. | Antiprotozoal cyclic tetrapeptides |
| US6955908B1 (en) * | 2000-06-21 | 2005-10-18 | Lambl Barbara B | Organism associated with nongonococcal urethritis |
| BR0207297A (pt) | 2001-02-15 | 2005-04-19 | King Pharmaceuticals Inc | Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| US8992999B2 (en) * | 2004-06-25 | 2015-03-31 | Alltech, Inc. | Methods and compositions for controlling parasitic infections of animals |
| FR2890560B1 (fr) * | 2005-09-13 | 2011-06-24 | Galderma Sa | Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation |
| FR2890559B1 (fr) * | 2005-09-13 | 2011-06-24 | Galderma Sa | Mousses dermatologiques a base de metronidazole et emulsions pour la preparation |
| DE102008027375A1 (de) * | 2008-06-09 | 2009-12-10 | Henkel Ag & Co. Kgaa | Bacitracin-Metall-Komplexe als Bleichkatalysatoren |
| EP2493493B1 (de) | 2009-10-28 | 2016-07-06 | Xellia Pharmaceuticals ApS | Neue bacitracin-antibiotika |
| PL434639A1 (pl) * | 2020-07-13 | 2022-01-17 | Adifeed Spółka Z Ograniczoną Odpowiedzialnością | Weterynaryjna kompozycja do leczenia i/lub zapobiegania chorób wywoływanych przez pierwotniaki u zwierząt, zawierająca olejek eteryczny oraz sposób jej wytwarzania |
| PL246688B1 (pl) * | 2020-07-13 | 2025-02-24 | Adifeed Spolka Z Ograniczona Odpowiedzialnoscia | Weterynaryjna kompozycja do leczenia i/lub zapobiegania chorób wywoływanych przez pierwotniaki u zwierząt zawierająca olejek eteryczny oraz sposób jej wytwarzania |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2594374A (en) * | 1949-10-11 | 1952-04-29 | Usa | Streptomycin-polymyxin-bacitracin composition |
| US2676134A (en) * | 1951-04-27 | 1954-04-20 | Commercial Solvents Corp | Therapeutic composition of neomycin and bacitracin |
| US2803584A (en) * | 1953-12-16 | 1957-08-20 | Commercial Solvents Corp | Zinc bacitracin-containing troche |
| US2985533A (en) * | 1958-06-13 | 1961-05-23 | Grain Processing Corp | Bacitracin product and processes utilizing manganese compounds |
| US3021217A (en) * | 1958-06-13 | 1962-02-13 | Grain Processing Corp | Bacitracin product and processes utilizing cobalt compounds |
| US2903357A (en) * | 1958-06-13 | 1959-09-08 | Grain Processing Corp | Bacitracin product and processes utilizing nickel compounds |
| US4101539A (en) * | 1977-10-17 | 1978-07-18 | Imc Chemical Group, Inc. | Bacitracin recovery process |
| US4693992A (en) * | 1985-08-26 | 1987-09-15 | International Minerals & Chemical Corp. | Bacitracin-metal-polyether antibiotic complexes |
| US5061689A (en) * | 1986-12-24 | 1991-10-29 | Bioderm, Inc. | Zinc bacitracin containing wound dressing |
-
1992
- 1992-10-23 US US07/967,471 patent/US5300491A/en not_active Expired - Lifetime
- 1992-10-29 IL IL10358492A patent/IL103584A/en not_active IP Right Cessation
- 1992-10-30 WO PCT/NO1992/000179 patent/WO1993008822A1/en not_active Ceased
- 1992-10-30 DE DE69230835T patent/DE69230835T2/de not_active Expired - Lifetime
- 1992-10-30 EP EP92923108A patent/EP0669831B1/de not_active Expired - Lifetime
- 1992-10-30 CA CA002122598A patent/CA2122598C/en not_active Expired - Lifetime
- 1992-10-30 RU RU94021356/14A patent/RU94021356A/ru unknown
- 1992-10-30 LT LTIP223A patent/LT3158B/lt not_active IP Right Cessation
- 1992-10-30 JP JP5508337A patent/JPH07500601A/ja active Pending
- 1992-10-30 NZ NZ244966A patent/NZ244966A/en not_active IP Right Cessation
- 1992-10-30 ZA ZA928421A patent/ZA928421B/xx unknown
- 1992-10-30 AT AT92923108T patent/ATE190847T1/de not_active IP Right Cessation
- 1992-10-30 CZ CZ941057A patent/CZ105794A3/cs unknown
- 1992-10-30 ES ES92923108T patent/ES2147554T3/es not_active Expired - Lifetime
- 1992-10-30 SK SK497-94A patent/SK49794A3/sk unknown
- 1992-10-30 AU AU29161/92A patent/AU664721B2/en not_active Expired
- 1992-10-31 LV LVP-92-177A patent/LV10392B/en unknown
-
1994
- 1994-11-23 EE EE9400161A patent/EE9400161A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE190847T1 (de) | 2000-04-15 |
| LV10392B (en) | 1995-08-20 |
| EE9400161A (et) | 1996-02-15 |
| CA2122598A1 (en) | 1993-05-13 |
| ZA928421B (en) | 1993-05-14 |
| DE69230835T2 (de) | 2000-11-02 |
| IL103584A0 (en) | 1993-03-15 |
| SK49794A3 (en) | 1995-06-07 |
| WO1993008822A1 (en) | 1993-05-13 |
| ES2147554T3 (es) | 2000-09-16 |
| LV10392A (lv) | 1995-02-20 |
| LT3158B (en) | 1995-01-31 |
| JPH07500601A (ja) | 1995-01-19 |
| CA2122598C (en) | 2000-06-20 |
| US5300491A (en) | 1994-04-05 |
| RU94021356A (ru) | 1996-08-10 |
| CZ105794A3 (en) | 1994-12-15 |
| NZ244966A (en) | 1995-05-26 |
| LTIP223A (en) | 1994-06-15 |
| AU2916192A (en) | 1993-06-07 |
| EP0669831B1 (de) | 2000-03-22 |
| AU664721B2 (en) | 1995-11-30 |
| DE69230835D1 (de) | 2000-04-27 |
| EP0669831A1 (de) | 1995-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |