IL103154A - Tramadol N-oxide, its enantiomers and pharmaceutical preparations containing them - Google Patents

Tramadol N-oxide, its enantiomers and pharmaceutical preparations containing them

Info

Publication number
IL103154A
IL103154A IL10315492A IL10315492A IL103154A IL 103154 A IL103154 A IL 103154A IL 10315492 A IL10315492 A IL 10315492A IL 10315492 A IL10315492 A IL 10315492A IL 103154 A IL103154 A IL 103154A
Authority
IL
Israel
Prior art keywords
tramadol
oxide
compound
pain
compositions
Prior art date
Application number
IL10315492A
Other languages
English (en)
Hebrew (he)
Other versions
IL103154A0 (en
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of IL103154A0 publication Critical patent/IL103154A0/xx
Publication of IL103154A publication Critical patent/IL103154A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Catching Or Destruction (AREA)
IL10315492A 1991-09-13 1992-09-13 Tramadol N-oxide, its enantiomers and pharmaceutical preparations containing them IL103154A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/759,259 US5223541A (en) 1991-09-13 1991-09-13 Tramadol n-oxide material, enantiomers and compositions thereof, and their use

Publications (2)

Publication Number Publication Date
IL103154A0 IL103154A0 (en) 1993-02-21
IL103154A true IL103154A (en) 1996-09-12

Family

ID=25054992

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10315492A IL103154A (en) 1991-09-13 1992-09-13 Tramadol N-oxide, its enantiomers and pharmaceutical preparations containing them

Country Status (23)

Country Link
US (1) US5223541A (hu)
EP (1) EP0532348B1 (hu)
JP (1) JP3115119B2 (hu)
KR (1) KR100241859B1 (hu)
CN (1) CN1032533C (hu)
AT (1) ATE132852T1 (hu)
AU (1) AU651000B2 (hu)
CA (1) CA2078028C (hu)
DE (1) DE69207526T2 (hu)
DK (1) DK0532348T3 (hu)
ES (1) ES2086079T3 (hu)
FI (1) FI111717B (hu)
GR (1) GR3019345T3 (hu)
HU (1) HU214321B (hu)
IL (1) IL103154A (hu)
MX (1) MX9205219A (hu)
MY (1) MY121910A (hu)
NO (1) NO178105C (hu)
NZ (1) NZ244309A (hu)
SG (1) SG63550A1 (hu)
TW (1) TW221968B (hu)
ZA (1) ZA926968B (hu)
ZW (1) ZW14592A1 (hu)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU651247B2 (en) 1991-09-06 1994-07-14 Mcneilab, Inc. Composition comprising a tramadol material and acetaminophen and its use
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US6017963A (en) * 1995-11-14 2000-01-25 Euro-Celtique, S.A. Formulation for intranasal administration
DK0996613T3 (da) 1997-07-15 2003-03-03 Russinsky Ltd Fremstilling af rent cis-tramadol-hydrochlorid
US6156342A (en) * 1998-05-26 2000-12-05 Andex Pharmaceuticals, Inc. Controlled release oral dosage form
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
AU764453B2 (en) 1999-10-29 2003-08-21 Euro-Celtique S.A. Controlled release hydrocodone formulations
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
CN101317825A (zh) 2000-10-30 2008-12-10 欧罗赛铁克股份有限公司 控释氢可酮制剂
US6974839B2 (en) 2001-03-16 2005-12-13 Dmi Biosciences, Inc. Method of delaying ejaculation
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US6649783B2 (en) * 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
US6780891B2 (en) 2001-11-30 2004-08-24 Sepracor Inc. Tramadol analogs and uses thereof
US9092841B2 (en) 2004-06-09 2015-07-28 Cognex Technology And Investment Llc Method and apparatus for visual detection and inspection of objects
US7940687B2 (en) 2005-11-16 2011-05-10 Qualcomm Incorporated Efficient partitioning of control and data fields
WO2008100933A2 (en) 2007-02-12 2008-08-21 Dmi Biosciences, Inc. Reducing side effects of tramadol
CA2677690C (en) * 2007-02-12 2012-05-15 James V. Winkler Treatment of comorbid premature ejaculation and erectile dysfunction
EP2170816A1 (en) * 2007-06-26 2010-04-07 Solvay Pharmaceuticals B.V. N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
US10475492B1 (en) 2018-07-27 2019-11-12 Macronix International Co., Ltd. Circuit and method for read latency control

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4017637A (en) * 1973-03-26 1977-04-12 American Home Products Corporation Benzylamine analgesics
DE3515349A1 (de) * 1985-04-27 1986-10-30 Messerschmitt-Bölkow-Blohm GmbH, 8012 Ottobrunn Elektrischer geber zur messung mechanischer groessen

Also Published As

Publication number Publication date
CA2078028A1 (en) 1993-03-14
DK0532348T3 (da) 1996-02-05
FI924084A (fi) 1993-03-14
NO923530D0 (no) 1992-09-11
AU651000B2 (en) 1994-07-07
KR930005969A (ko) 1993-04-20
DE69207526D1 (de) 1996-02-22
HUT65476A (en) 1994-06-28
EP0532348A3 (en) 1993-05-26
GR3019345T3 (en) 1996-06-30
HU214321B (hu) 1998-03-02
FI111717B (fi) 2003-09-15
AU2355792A (en) 1993-03-18
SG63550A1 (en) 1999-03-30
NO923530L (no) 1993-03-15
CA2078028C (en) 2003-04-29
NO178105B (no) 1995-10-16
IL103154A0 (en) 1993-02-21
TW221968B (hu) 1994-04-01
FI924084A0 (fi) 1992-09-11
ZA926968B (en) 1994-03-11
NZ244309A (en) 1994-10-26
JPH06122668A (ja) 1994-05-06
HU9202918D0 (en) 1992-11-30
JP3115119B2 (ja) 2000-12-04
ATE132852T1 (de) 1996-01-15
CN1032533C (zh) 1996-08-14
EP0532348B1 (en) 1996-01-10
CN1071913A (zh) 1993-05-12
NO178105C (no) 1996-01-24
DE69207526T2 (de) 1996-07-04
ES2086079T3 (es) 1996-06-16
MY121910A (en) 2006-03-31
EP0532348A2 (en) 1993-03-17
ZW14592A1 (en) 1994-05-11
MX9205219A (es) 1994-02-28
KR100241859B1 (ko) 2000-02-01
US5223541A (en) 1993-06-29

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