DK0532348T3 - Tramadol-N-oxidmateriale, enantiomerer og præparater deraf og deres anvendelse - Google Patents

Tramadol-N-oxidmateriale, enantiomerer og præparater deraf og deres anvendelse

Info

Publication number
DK0532348T3
DK0532348T3 DK92308298.6T DK92308298T DK0532348T3 DK 0532348 T3 DK0532348 T3 DK 0532348T3 DK 92308298 T DK92308298 T DK 92308298T DK 0532348 T3 DK0532348 T3 DK 0532348T3
Authority
DK
Denmark
Prior art keywords
tramadol
oxide material
enantiomers
compositions
preparations
Prior art date
Application number
DK92308298.6T
Other languages
English (en)
Inventor
Cynthia A Maryanoff
Frank J Villani
Robert B Raffa
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Application granted granted Critical
Publication of DK0532348T3 publication Critical patent/DK0532348T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
DK92308298.6T 1991-09-13 1992-09-11 Tramadol-N-oxidmateriale, enantiomerer og præparater deraf og deres anvendelse DK0532348T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/759,259 US5223541A (en) 1991-09-13 1991-09-13 Tramadol n-oxide material, enantiomers and compositions thereof, and their use

Publications (1)

Publication Number Publication Date
DK0532348T3 true DK0532348T3 (da) 1996-02-05

Family

ID=25054992

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92308298.6T DK0532348T3 (da) 1991-09-13 1992-09-11 Tramadol-N-oxidmateriale, enantiomerer og præparater deraf og deres anvendelse

Country Status (23)

Country Link
US (1) US5223541A (da)
EP (1) EP0532348B1 (da)
JP (1) JP3115119B2 (da)
KR (1) KR100241859B1 (da)
CN (1) CN1032533C (da)
AT (1) ATE132852T1 (da)
AU (1) AU651000B2 (da)
CA (1) CA2078028C (da)
DE (1) DE69207526T2 (da)
DK (1) DK0532348T3 (da)
ES (1) ES2086079T3 (da)
FI (1) FI111717B (da)
GR (1) GR3019345T3 (da)
HU (1) HU214321B (da)
IL (1) IL103154A (da)
MX (1) MX9205219A (da)
MY (1) MY121910A (da)
NO (1) NO178105C (da)
NZ (1) NZ244309A (da)
SG (1) SG63550A1 (da)
TW (1) TW221968B (da)
ZA (1) ZA926968B (da)
ZW (1) ZW14592A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2120451T7 (es) 1991-09-06 2009-11-05 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Composicion que comprende un compuesto de tramadol y acetaminofeno, y su uso.
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US6017963A (en) * 1995-11-14 2000-01-25 Euro-Celtique, S.A. Formulation for intranasal administration
WO1999003820A1 (en) 1997-07-15 1999-01-28 Russinsky Limited Tramadol, salts thereof and process for their preparation
US6156342A (en) * 1998-05-26 2000-12-05 Andex Pharmaceuticals, Inc. Controlled release oral dosage form
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP1623703B1 (en) 1999-10-29 2011-10-05 Euro-Celtique S.A. Controlled release hydrocodone formulations
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
KR100968128B1 (ko) 2000-10-30 2010-07-06 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
CA2440920C (en) * 2001-03-16 2012-01-24 David Bar-Or Use of tramadol to delay ejaculation
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US6649783B2 (en) 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
AU2002364517A1 (en) 2001-11-30 2003-06-17 Sepracor Inc. Tramadol analogs and uses thereof
US9092841B2 (en) 2004-06-09 2015-07-28 Cognex Technology And Investment Llc Method and apparatus for visual detection and inspection of objects
US7940687B2 (en) 2005-11-16 2011-05-10 Qualcomm Incorporated Efficient partitioning of control and data fields
EP2486921A1 (en) 2007-02-12 2012-08-15 DMI Biosciences, Inc. Reducing Side Effects of Tramadol
KR20090121315A (ko) 2007-02-12 2009-11-25 디엠아이 바이오사이언시스 인코포레이티드 조루 및 발기부전을 동시에 치료하는 방법
CA2699961A1 (en) * 2007-06-26 2008-12-31 Solvay Pharmaceuticals B.V. N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
US10475492B1 (en) 2018-07-27 2019-11-12 Macronix International Co., Ltd. Circuit and method for read latency control

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4017637A (en) * 1973-03-26 1977-04-12 American Home Products Corporation Benzylamine analgesics
DE3515349A1 (de) * 1985-04-27 1986-10-30 Messerschmitt-Bölkow-Blohm GmbH, 8012 Ottobrunn Elektrischer geber zur messung mechanischer groessen

Also Published As

Publication number Publication date
EP0532348A3 (en) 1993-05-26
HU9202918D0 (en) 1992-11-30
HUT65476A (en) 1994-06-28
EP0532348B1 (en) 1996-01-10
DE69207526D1 (de) 1996-02-22
IL103154A (en) 1996-09-12
ES2086079T3 (es) 1996-06-16
HU214321B (hu) 1998-03-02
FI924084A0 (fi) 1992-09-11
JPH06122668A (ja) 1994-05-06
NZ244309A (en) 1994-10-26
AU651000B2 (en) 1994-07-07
NO923530D0 (no) 1992-09-11
ZA926968B (en) 1994-03-11
CN1071913A (zh) 1993-05-12
FI111717B (fi) 2003-09-15
ATE132852T1 (de) 1996-01-15
NO923530L (no) 1993-03-15
AU2355792A (en) 1993-03-18
EP0532348A2 (en) 1993-03-17
NO178105C (no) 1996-01-24
US5223541A (en) 1993-06-29
KR930005969A (ko) 1993-04-20
NO178105B (no) 1995-10-16
IL103154A0 (en) 1993-02-21
DE69207526T2 (de) 1996-07-04
ZW14592A1 (en) 1994-05-11
MY121910A (en) 2006-03-31
KR100241859B1 (ko) 2000-02-01
JP3115119B2 (ja) 2000-12-04
CA2078028A1 (en) 1993-03-14
TW221968B (da) 1994-04-01
CA2078028C (en) 2003-04-29
FI924084A (fi) 1993-03-14
SG63550A1 (en) 1999-03-30
CN1032533C (zh) 1996-08-14
GR3019345T3 (en) 1996-06-30
MX9205219A (es) 1994-02-28

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