IL102533A0 - Amino substituted piperazine derivatives and pharmaceutical compositions containing them - Google Patents
Amino substituted piperazine derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL102533A0 IL102533A0 IL102533A IL10253392A IL102533A0 IL 102533 A0 IL102533 A0 IL 102533A0 IL 102533 A IL102533 A IL 102533A IL 10253392 A IL10253392 A IL 10253392A IL 102533 A0 IL102533 A0 IL 102533A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- amino substituted
- piperazine derivatives
- substituted piperazine
- Prior art date
Links
- -1 Amino substituted piperazine derivatives Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH216091 | 1991-07-19 | ||
| CH134092 | 1992-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL102533A0 true IL102533A0 (en) | 1993-01-14 |
Family
ID=25687395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL102533A IL102533A0 (en) | 1991-07-19 | 1992-07-17 | Amino substituted piperazine derivatives and pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5286728A (no) |
| EP (1) | EP0524146A1 (no) |
| JP (1) | JPH05202014A (no) |
| KR (1) | KR930002330A (no) |
| AU (1) | AU650989B2 (no) |
| CA (1) | CA2074154A1 (no) |
| CZ (1) | CZ222392A3 (no) |
| FI (1) | FI923280A (no) |
| HU (1) | HUT67047A (no) |
| IE (1) | IE922336A1 (no) |
| IL (1) | IL102533A0 (no) |
| MX (1) | MX9204171A (no) |
| NO (1) | NO922853L (no) |
| NZ (1) | NZ243607A (no) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0489690A1 (de) * | 1990-12-05 | 1992-06-10 | Ciba-Geigy Ag | Substituierte N-Benzoyl-N'-(2-phenylethyl)-piperazine |
| US5384319A (en) * | 1993-01-06 | 1995-01-24 | Ciba-Geigy Corporation | Aminoalkylphenyl compounds |
| US5380726A (en) * | 1993-01-15 | 1995-01-10 | Ciba-Geigy Corporation | Substituted dialkylthio ethers |
| US5371171A (en) * | 1993-03-05 | 1994-12-06 | Baylor University | Poly(methylene oxalate) and precursors thereto |
| US5561212A (en) * | 1993-03-05 | 1996-10-01 | Baylor University | Poly(methylene oxalate), a new composition of matter |
| WO1996029088A1 (en) * | 1995-03-23 | 1996-09-26 | Affymax Technologies N.V. | Novel piperazine derivatives as type il-1 receptor antagonists |
| FR2740134B1 (fr) * | 1995-10-18 | 1998-01-09 | Pf Medicament | Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant |
| FR2744449B1 (fr) * | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperazines aromatiques derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
| FR2744450A1 (fr) * | 1996-02-02 | 1997-08-08 | Pf Medicament | Nouvelles naphtylpiperazines derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
| EP0968200A1 (en) * | 1997-02-24 | 2000-01-05 | ZymoGenetics, Inc. | Calcitonin mimetics |
| ATE293603T1 (de) | 1997-10-14 | 2005-05-15 | Mitsubishi Pharma Corp | Piperazin-verbindungen und ihre medizinische verwendung |
| WO2000042852A1 (en) * | 1999-01-25 | 2000-07-27 | Smithkline Beecham Corporation | Compounds and methods |
| UY27003A1 (es) | 2000-11-06 | 2002-07-31 | Schering Ag | Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer |
| US20050119251A1 (en) * | 2001-12-21 | 2005-06-02 | Jian-Min Fu | Nicotinamide derivatives and their use as therapeutic agents |
| EA007272B1 (ru) * | 2002-03-13 | 2006-08-25 | Янссен Фармацевтика Н. В. | Новые ингибиторы гистондеацетилазы |
| AU2005329423A1 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| TW200626154A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| CN101084207A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途 |
| CN101083982A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物 |
| TW200626155A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| CN101083986A (zh) * | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 双环杂环衍生物及其作为硬脂酰CoA去饱和酶(SCD)抑制剂的用途 |
| WO2006034279A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as therapeutic agents |
| BRPI0515478A (pt) | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e seu uso como mediadores de estearoil-coa-desaturase |
| BRPI0611187A2 (pt) | 2005-06-03 | 2010-08-24 | Xenon Pharmaceuticals Inc | derivados aminotiazàis como inibidores da estearoil-coa desaturase humana |
| CN101597278B (zh) * | 2008-06-04 | 2013-04-17 | 中国中化股份有限公司 | 酰胺类化合物及其制备与应用 |
| AU2018289303B2 (en) | 2017-06-20 | 2023-12-21 | Imbria Pharmaceuticals, Inc. | Compositions and methods for increasing efficiency of cardiac metabolism |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL105768C (no) * | 1959-02-25 | |||
| CH590262A5 (no) * | 1973-07-10 | 1977-07-29 | Ciba Geigy Ag | |
| DE2365988B2 (de) * | 1973-07-12 | 1978-09-07 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | Verfahren zur Herstellung von N-Dialkylaminoäthyl-2-alkoxy-4-amino-5-chlor-benzoesäureamiden |
| CY1344A (en) * | 1978-08-10 | 1987-01-16 | Ciba Geigy Ag | Substituted anthranilic acid amides,process for their preparation,and pharmaceutical compositions containing them |
| MY102447A (en) * | 1986-06-16 | 1992-06-30 | Ciba Geigy Ag | Disubtituted piperazines |
| AU606808B2 (en) * | 1988-06-29 | 1991-02-14 | Otsuka Pharmaceutical Factory, Inc. | Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same |
| US5051423A (en) * | 1988-07-13 | 1991-09-24 | Schering Ag | Derivatized alkanolamines as cardiovascular agents |
| EP0385043A1 (en) * | 1989-02-28 | 1990-09-05 | Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. (Faes) | New derivatives of 4-substituted piperazines |
| EP0489690A1 (de) * | 1990-12-05 | 1992-06-10 | Ciba-Geigy Ag | Substituierte N-Benzoyl-N'-(2-phenylethyl)-piperazine |
-
1992
- 1992-07-10 EP EP92810525A patent/EP0524146A1/de not_active Withdrawn
- 1992-07-14 US US07/913,277 patent/US5286728A/en not_active Expired - Fee Related
- 1992-07-15 AU AU20317/92A patent/AU650989B2/en not_active Ceased
- 1992-07-16 MX MX9204171A patent/MX9204171A/es unknown
- 1992-07-16 CZ CS922223A patent/CZ222392A3/cs unknown
- 1992-07-17 FI FI923280A patent/FI923280A/fi not_active Application Discontinuation
- 1992-07-17 HU HU9202359A patent/HUT67047A/hu unknown
- 1992-07-17 JP JP4190894A patent/JPH05202014A/ja active Pending
- 1992-07-17 CA CA002074154A patent/CA2074154A1/en not_active Abandoned
- 1992-07-17 NZ NZ243607A patent/NZ243607A/en unknown
- 1992-07-17 NO NO92922853A patent/NO922853L/no unknown
- 1992-07-17 IL IL102533A patent/IL102533A0/xx unknown
- 1992-07-17 IE IE233692A patent/IE922336A1/en not_active Application Discontinuation
- 1992-07-18 KR KR1019920012804A patent/KR930002330A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IE922336A1 (en) | 1993-01-27 |
| NZ243607A (en) | 1995-02-24 |
| AU2031792A (en) | 1993-01-21 |
| JPH05202014A (ja) | 1993-08-10 |
| US5286728A (en) | 1994-02-15 |
| NO922853L (no) | 1993-01-20 |
| AU650989B2 (en) | 1994-07-07 |
| EP0524146A1 (de) | 1993-01-20 |
| CZ222392A3 (en) | 1993-02-17 |
| FI923280A0 (fi) | 1992-07-17 |
| NO922853D0 (no) | 1992-07-17 |
| HUT67047A (en) | 1995-01-30 |
| HU9202359D0 (en) | 1992-10-28 |
| MX9204171A (es) | 1993-01-01 |
| FI923280A (fi) | 1993-01-20 |
| CA2074154A1 (en) | 1993-01-20 |
| KR930002330A (ko) | 1993-02-23 |
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