IL101244A - A crystalline form of cyclosporine and pharmaceutical preparations containing it for pulmonary administration - Google Patents
A crystalline form of cyclosporine and pharmaceutical preparations containing it for pulmonary administrationInfo
- Publication number
- IL101244A IL101244A IL10124492A IL10124492A IL101244A IL 101244 A IL101244 A IL 101244A IL 10124492 A IL10124492 A IL 10124492A IL 10124492 A IL10124492 A IL 10124492A IL 101244 A IL101244 A IL 101244A
- Authority
- IL
- Israel
- Prior art keywords
- iii
- ciclosporin
- administration
- pulmonary administration
- particulate form
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919105705A GB9105705D0 (en) | 1991-03-18 | 1991-03-18 | Improvements in or relating to organic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IL101244A0 IL101244A0 (en) | 1992-11-15 |
IL101244A true IL101244A (en) | 1996-10-31 |
Family
ID=10691762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10124492A IL101244A (en) | 1991-03-18 | 1992-03-16 | A crystalline form of cyclosporine and pharmaceutical preparations containing it for pulmonary administration |
Country Status (29)
Country | Link |
---|---|
US (1) | US5719123A (fr) |
EP (1) | EP0504760B1 (fr) |
JP (1) | JP2549794B2 (fr) |
KR (1) | KR920017644A (fr) |
AT (1) | AT404553B (fr) |
AU (1) | AU658172B2 (fr) |
CA (1) | CA2063106C (fr) |
CH (1) | CH685229A5 (fr) |
CZ (1) | CZ281260B6 (fr) |
DE (1) | DE4208258B4 (fr) |
DK (1) | DK0504760T3 (fr) |
ES (1) | ES2093130T3 (fr) |
FI (1) | FI921125A (fr) |
FR (1) | FR2674249A1 (fr) |
GB (2) | GB9105705D0 (fr) |
GR (1) | GR3021497T3 (fr) |
HU (1) | HU208492B (fr) |
IE (1) | IE67627B1 (fr) |
IL (1) | IL101244A (fr) |
IT (1) | IT1255040B (fr) |
LU (1) | LU88087A1 (fr) |
MX (1) | MX9201141A (fr) |
NO (1) | NO310754B1 (fr) |
NZ (1) | NZ241975A (fr) |
RU (1) | RU2098122C1 (fr) |
SA (1) | SA92120536B1 (fr) |
SK (1) | SK279576B6 (fr) |
TW (1) | TW215901B (fr) |
ZA (1) | ZA921987B (fr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5837677B2 (ja) * | 1981-01-13 | 1983-08-17 | 松下電器産業株式会社 | 誘導加熱調理器 |
JPH07111905B2 (ja) * | 1987-07-23 | 1995-11-29 | 株式会社東芝 | 誘導加熱調理器の負荷適否検知回路 |
WO1993025198A1 (fr) * | 1992-06-12 | 1993-12-23 | Teijin Limited | Poudre ultra-fine pour inhalation et production de cette poudre |
US5512269A (en) * | 1993-06-09 | 1996-04-30 | Burroughs Wellcome, Co. | Method of treating retained pulmonary secretions |
PE44995A1 (es) * | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
JP2000514085A (ja) * | 1996-07-08 | 2000-10-24 | ローヌ―プーラン・ロウラー・リミテッド | 医薬シクロスポリンaエーロゾル溶液処方物 |
ZA9711732B (en) | 1996-12-31 | 1998-12-28 | Quadrant Holdings Cambridge | Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery |
US5898028A (en) * | 1997-03-20 | 1999-04-27 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
TW581681B (en) * | 1998-02-20 | 2004-04-01 | Nektar Therapeutics | Liquid crystal forms of cyclosporin |
US20020006901A1 (en) * | 1999-02-05 | 2002-01-17 | Aldo T. Iacono | Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease |
FI20002217A (fi) * | 1999-12-30 | 2001-07-01 | Orion Yhtymae Oyj | Inhalaatiopartikkelit |
FI20010115A0 (fi) * | 2001-01-18 | 2001-01-18 | Orion Corp | Menetelmä nanopartikkelien valmistamiseksi |
EP1435910B9 (fr) * | 2001-10-19 | 2010-02-03 | Isotechnika Inc. | Nouveaux preconcentres en microemulsion d'analogues de cyclosporine |
WO2004069223A2 (fr) * | 2003-02-06 | 2004-08-19 | Cipla Ltd | Compositions pharmaceutiques et leurs utilisations |
CA2516733C (fr) * | 2003-02-21 | 2011-09-27 | The University Of Bath | Procede de production de particules |
US20050059583A1 (en) * | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
US20060078623A1 (en) * | 2004-08-13 | 2006-04-13 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
US7151085B2 (en) | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
US20080052114A1 (en) * | 2005-11-30 | 2008-02-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational systems and methods related to nutraceuticals |
US8340944B2 (en) * | 2005-11-30 | 2012-12-25 | The Invention Science Fund I, Llc | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
US8000981B2 (en) | 2005-11-30 | 2011-08-16 | The Invention Science Fund I, Llc | Methods and systems related to receiving nutraceutical associated information |
US7974856B2 (en) | 2005-11-30 | 2011-07-05 | The Invention Science Fund I, Llc | Computational systems and methods related to nutraceuticals |
US20070174128A1 (en) * | 2005-11-30 | 2007-07-26 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging |
US20080033763A1 (en) * | 2005-11-30 | 2008-02-07 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Methods and systems related to receiving nutraceutical associated information |
US8068991B2 (en) * | 2005-11-30 | 2011-11-29 | The Invention Science Fund I, Llc | Systems and methods for transmitting pathogen related information and responding |
US10296720B2 (en) * | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
US7927787B2 (en) * | 2006-06-28 | 2011-04-19 | The Invention Science Fund I, Llc | Methods and systems for analysis of nutraceutical associated components |
US20070124176A1 (en) * | 2005-11-30 | 2007-05-31 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
US7827042B2 (en) * | 2005-11-30 | 2010-11-02 | The Invention Science Fund I, Inc | Methods and systems related to transmission of nutraceutical associated information |
US20070124218A1 (en) * | 2005-11-30 | 2007-05-31 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational and/or control systems related to individualized nutraceutical selection and packaging |
US20080004905A1 (en) * | 2006-06-28 | 2008-01-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Methods and systems for analysis of nutraceutical associated components |
US20070289258A1 (en) * | 2006-06-14 | 2007-12-20 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Individualized pharmaceutical selection and packaging |
US20070136092A1 (en) * | 2005-11-30 | 2007-06-14 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging |
US20110145009A1 (en) * | 2005-11-30 | 2011-06-16 | Jung Edward K Y | Methods and systems related to transmission of nutraceutical associatd information |
US8297028B2 (en) | 2006-06-14 | 2012-10-30 | The Invention Science Fund I, Llc | Individualized pharmaceutical selection and packaging |
US20080114577A1 (en) * | 2005-11-30 | 2008-05-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Computational methods and systems associated with nutraceutical related assays |
DE102006051512A1 (de) | 2005-12-06 | 2007-06-14 | Pari GmbH Spezialisten für effektive Inhalation | Pharmazeutische Medikamentenzusammensetzungen mit Cyclosporin |
US20070219127A1 (en) * | 2006-03-20 | 2007-09-20 | Walt John G | Cyclosporin a compositions |
EP2714720B1 (fr) * | 2011-05-27 | 2018-12-26 | Allergan, Inc. | Forme cristalline de cyclosporine a, procédés de préparation et procédés d'utilisation associés |
JO3410B1 (ar) | 2011-06-07 | 2019-10-20 | Otsuka Pharma Co Ltd | تركيبة أريبيبرازول مجفف بالتبريد |
KR102072252B1 (ko) * | 2011-11-15 | 2020-01-31 | 알러간, 인코포레이티드 | 사이클로스포린 a 제2형 및 그의 제조방법 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU203564B (en) * | 1987-12-21 | 1991-08-28 | Sandoz Ag | Process for producing new orthorombos cyclosporin without solvatation |
CH679119A5 (fr) * | 1988-05-13 | 1991-12-31 | Sandoz Ag | |
GB8916901D0 (en) * | 1989-07-24 | 1989-09-06 | Sandoz Ltd | Improvements in or relating to organic compounds |
-
1991
- 1991-03-18 GB GB919105705A patent/GB9105705D0/en active Pending
-
1992
- 1992-03-04 HU HU9200735A patent/HU208492B/hu not_active IP Right Cessation
- 1992-03-12 CH CH807/92A patent/CH685229A5/de not_active IP Right Cessation
- 1992-03-13 GB GB9205554A patent/GB2253853B/en not_active Expired - Fee Related
- 1992-03-14 ES ES92104426T patent/ES2093130T3/es not_active Expired - Lifetime
- 1992-03-14 EP EP92104426A patent/EP0504760B1/fr not_active Expired - Lifetime
- 1992-03-14 DE DE4208258A patent/DE4208258B4/de not_active Expired - Lifetime
- 1992-03-14 DK DK92104426.9T patent/DK0504760T3/da active
- 1992-03-16 MX MX9201141A patent/MX9201141A/es unknown
- 1992-03-16 CZ CS92785A patent/CZ281260B6/cs unknown
- 1992-03-16 NO NO19921012A patent/NO310754B1/no not_active IP Right Cessation
- 1992-03-16 FR FR9203116A patent/FR2674249A1/fr active Granted
- 1992-03-16 NZ NZ241975A patent/NZ241975A/en unknown
- 1992-03-16 FI FI921125A patent/FI921125A/fi unknown
- 1992-03-16 IE IE920839A patent/IE67627B1/en not_active IP Right Cessation
- 1992-03-16 IL IL10124492A patent/IL101244A/en not_active IP Right Cessation
- 1992-03-16 AU AU12940/92A patent/AU658172B2/en not_active Ceased
- 1992-03-16 CA CA002063106A patent/CA2063106C/fr not_active Expired - Lifetime
- 1992-03-16 SK SK785-92A patent/SK279576B6/sk not_active IP Right Cessation
- 1992-03-17 JP JP4060142A patent/JP2549794B2/ja not_active Expired - Lifetime
- 1992-03-17 KR KR1019920004494A patent/KR920017644A/ko not_active Application Discontinuation
- 1992-03-17 IT ITRM920181A patent/IT1255040B/it active IP Right Grant
- 1992-03-17 RU SU925011418A patent/RU2098122C1/ru active
- 1992-03-17 LU LU88087A patent/LU88087A1/fr unknown
- 1992-03-17 AT AT0053492A patent/AT404553B/de not_active IP Right Cessation
- 1992-03-18 ZA ZA921987A patent/ZA921987B/xx unknown
- 1992-03-19 TW TW081102058A patent/TW215901B/zh active
- 1992-05-20 SA SA92120536A patent/SA92120536B1/ar unknown
-
1994
- 1994-06-06 US US08/254,094 patent/US5719123A/en not_active Expired - Lifetime
-
1996
- 1996-10-30 GR GR960402866T patent/GR3021497T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
HC | Change of name of proprietor(s) | ||
KB | Patent renewed | ||
RH | Patent void | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |