IL101087A - History of Imidazol-2-On-Transformed Preparation and Pharmaceutical Preparations Containing Them - Google Patents

History of Imidazol-2-On-Transformed Preparation and Pharmaceutical Preparations Containing Them

Info

Publication number
IL101087A
IL101087A IL10108792A IL10108792A IL101087A IL 101087 A IL101087 A IL 101087A IL 10108792 A IL10108792 A IL 10108792A IL 10108792 A IL10108792 A IL 10108792A IL 101087 A IL101087 A IL 101087A
Authority
IL
Israel
Prior art keywords
formula
compound
hydrogen
alkyl
azabicyclo
Prior art date
Application number
IL10108792A
Other languages
English (en)
Hebrew (he)
Other versions
IL101087A0 (en
Inventor
Mario Varasi
Franco Heidempergher
Nicola Carfagna
Ruggero Fariello
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL101087A0 publication Critical patent/IL101087A0/xx
Publication of IL101087A publication Critical patent/IL101087A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dental Preparations (AREA)
  • Cephalosporin Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
IL10108792A 1991-03-27 1992-02-27 History of Imidazol-2-On-Transformed Preparation and Pharmaceutical Preparations Containing Them IL101087A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919106571A GB9106571D0 (en) 1991-03-27 1991-03-27 Derivatives of substituted imidazol-2-one and process for their preparation

Publications (2)

Publication Number Publication Date
IL101087A0 IL101087A0 (en) 1992-11-15
IL101087A true IL101087A (en) 1996-01-31

Family

ID=10692325

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10108792A IL101087A (en) 1991-03-27 1992-02-27 History of Imidazol-2-On-Transformed Preparation and Pharmaceutical Preparations Containing Them

Country Status (21)

Country Link
US (2) US5242929A (no)
EP (1) EP0505778B1 (no)
JP (1) JP3315144B2 (no)
KR (1) KR920018030A (no)
AT (1) ATE128980T1 (no)
AU (1) AU644720B2 (no)
CA (1) CA2062271C (no)
DE (1) DE69205312T2 (no)
DK (1) DK0505778T3 (no)
ES (1) ES2080975T3 (no)
FI (1) FI921308A (no)
GB (1) GB9106571D0 (no)
GR (1) GR3018342T3 (no)
HU (1) HU208135B (no)
IE (1) IE76918B1 (no)
IL (1) IL101087A (no)
MX (1) MX9201279A (no)
MY (1) MY108681A (no)
NZ (1) NZ241785A (no)
RU (1) RU2056418C1 (no)
TW (1) TW198719B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212486D0 (en) * 1992-06-12 1992-07-22 Erba Carlo Spa Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
SK94393A3 (en) * 1992-09-11 1994-08-10 Thomae Gmbh Dr K Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those
GB9224144D0 (en) * 1992-11-18 1993-01-06 Erba Carlo Spa Phenyl-imidazolidinone derivatives and process for their preparation
DE4332168A1 (de) * 1993-02-22 1995-03-23 Thomae Gmbh Dr K Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
JP3916093B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 光学活性イミダゾリジノン誘導体とその製造方法
JP3916092B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
GB9410441D0 (en) * 1994-05-25 1994-07-13 Erba Carlo Spa Azabicycloakyl derivatives of imidazo (1,5-a) indol-3-one and process for their preparation
US6347538B1 (en) * 2000-11-29 2002-02-19 Gerald J. Doiron Locking mechanism for weapons
CA2473392A1 (en) * 2002-01-18 2003-07-31 Aryx Therapeutics 5-ht3 receptor antagonists and methods of use
MA37975B2 (fr) 2012-09-11 2021-03-31 Genzyme Corp Inhibiteurs de synthase de glucosylcéramide
AU2021215396A1 (en) 2020-02-03 2022-09-29 Genzyme Corporation Methods for treating neurological symptoms associated with lysosomal storage diseases
IL300090A (en) 2020-07-24 2023-03-01 Genzyme Corp Pharmaceutical preparations containing VENGLUSTAT

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3702327A (en) * 1970-12-28 1972-11-07 Aldrich Chem Co Inc N-beta-1-(3-phenylimidazolidin-2-one)ethyl 4,4-ethylene dioxypiperidines
EP0235878A3 (en) * 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
DE3785507T2 (de) * 1986-07-31 1993-07-29 Beecham Group Plc Azabicyclische verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
AU611976B2 (en) * 1987-12-24 1991-06-27 John Wyeth & Brother Limited Aroyl urea and carbamic acid derivatives of azabicyclo compounds
IT1230881B (it) * 1989-06-20 1991-11-08 Angeli Inst Spa Derivati del r(-) 3-chinuclidinolo
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB8922622D0 (en) * 1989-10-07 1989-11-22 Wyeth John & Brother Ltd Aroylureas

Also Published As

Publication number Publication date
MX9201279A (es) 1992-10-01
IE920961A1 (en) 1992-10-07
AU644720B2 (en) 1993-12-16
TW198719B (no) 1993-01-21
EP0505778A1 (en) 1992-09-30
EP0505778B1 (en) 1995-10-11
FI921308A (fi) 1992-09-28
GR3018342T3 (en) 1996-03-31
ES2080975T3 (es) 1996-02-16
RU2056418C1 (ru) 1996-03-20
CA2062271A1 (en) 1992-09-28
JP3315144B2 (ja) 2002-08-19
DE69205312T2 (de) 1996-03-14
HUT61021A (en) 1992-11-30
IL101087A0 (en) 1992-11-15
KR920018030A (ko) 1992-10-21
DK0505778T3 (da) 1995-12-11
HU9200946D0 (en) 1992-05-28
CA2062271C (en) 2003-04-08
MY108681A (en) 1996-10-31
US5401750A (en) 1995-03-28
GB9106571D0 (en) 1991-05-15
FI921308A0 (fi) 1992-03-25
DE69205312D1 (de) 1995-11-16
JPH0570457A (ja) 1993-03-23
ATE128980T1 (de) 1995-10-15
AU1121492A (en) 1992-10-01
US5242929A (en) 1993-09-07
NZ241785A (en) 1994-01-26
HU208135B (en) 1993-08-30
IE76918B1 (en) 1997-11-05

Similar Documents

Publication Publication Date Title
US4789673A (en) Heterocyclic carboxylic acid amides and esters
US4910207A (en) Method of treating psychosis with N-quinuclidinyl-benzamides
CA2062271C (en) Derivatives of substituted imidazol-2-one and process for their preparation
US5362740A (en) Dihydrobenzofuran carboxamides and process for their preparation
US5637596A (en) Azabicycloalkyl derivatives of imidazo[1,5-a]indol-3-one and process for their preparation
US5364854A (en) Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
WO1995032208A1 (en) IMIDAZOLYLALKYL DERIVATIVES OF IMIDAZOL(5,1-c)(1,4)BENZOXAZIN-1-ONE AND THEIR USE AS THERAPEUTIC AGENTS
US5424328A (en) Phenyl-imidazolidinone derivatives
US5874457A (en) Imidazolylalkyl derivatives of imidazo 1,5-a!indol-3-one

Legal Events

Date Code Title Description
FF Patent granted
HC Change of name of proprietor(s)
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees