IL101082A - Process for converting trans-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-n-methyl-4- (3,4-di- chlorophenyl)-1,2,3,4- tetrahydro-1- naphthaleneamine - Google Patents

Process for converting trans-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-n-methyl-4- (3,4-di- chlorophenyl)-1,2,3,4- tetrahydro-1- naphthaleneamine

Info

Publication number
IL101082A
IL101082A IL10108292A IL10108292A IL101082A IL 101082 A IL101082 A IL 101082A IL 10108292 A IL10108292 A IL 10108292A IL 10108292 A IL10108292 A IL 10108292A IL 101082 A IL101082 A IL 101082A
Authority
IL
Israel
Prior art keywords
tetrahydro
methyl
cis
naphthaleneamine
dichlorophenyl
Prior art date
Application number
IL10108292A
Other languages
English (en)
Other versions
IL101082A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL101082A0 publication Critical patent/IL101082A0/xx
Publication of IL101082A publication Critical patent/IL101082A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/38—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Lubricants (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
IL10108292A 1991-03-06 1992-02-27 Process for converting trans-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-n-methyl-4- (3,4-di- chlorophenyl)-1,2,3,4- tetrahydro-1- naphthaleneamine IL101082A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/665,506 US5082970A (en) 1991-03-06 1991-03-06 Process for recycling amine isomer

Publications (2)

Publication Number Publication Date
IL101082A0 IL101082A0 (en) 1992-11-15
IL101082A true IL101082A (en) 1996-01-31

Family

ID=24670381

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10108292A IL101082A (en) 1991-03-06 1992-02-27 Process for converting trans-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine to cis-n-methyl-4- (3,4-di- chlorophenyl)-1,2,3,4- tetrahydro-1- naphthaleneamine

Country Status (29)

Country Link
US (1) US5082970A (pl)
EP (1) EP0575507B1 (pl)
JP (1) JP2736167B2 (pl)
KR (1) KR0169750B1 (pl)
CN (1) CN1040641C (pl)
AT (1) ATE133655T1 (pl)
AU (1) AU647620B2 (pl)
BR (1) BR9205727A (pl)
CA (1) CA2105393C (pl)
CZ (1) CZ285170B6 (pl)
DE (1) DE69208080T2 (pl)
DK (1) DK0575507T3 (pl)
EG (1) EG20002A (pl)
ES (1) ES2083741T3 (pl)
FI (1) FI112074B (pl)
GR (1) GR3019040T3 (pl)
HU (1) HU217064B (pl)
IE (1) IE70061B1 (pl)
IL (1) IL101082A (pl)
MX (1) MX9200953A (pl)
MY (1) MY106803A (pl)
NO (1) NO179609C (pl)
NZ (1) NZ241844A (pl)
PL (1) PL166756B1 (pl)
PT (1) PT100189B (pl)
RU (1) RU2079483C1 (pl)
WO (1) WO1992015552A1 (pl)
YU (1) YU48743B (pl)
ZA (1) ZA921641B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248699A (en) * 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
CA2176500C (en) * 1993-11-30 1999-09-28 George J. Quallich Process for preparing a chiral tetralone
US5597826A (en) 1994-09-14 1997-01-28 Pfizer Inc. Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist
HU222341B1 (hu) * 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
US6727283B2 (en) 1998-10-13 2004-04-27 Pfizer Inc. Sertraline oral concentrate
IL132500A0 (en) 1998-10-29 2001-03-19 Pfizer Prod Inc Stereoselective microbial reduction of a racemic tetralone
US6500987B1 (en) 1998-11-27 2002-12-31 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
AU1633600A (en) * 1998-11-27 2000-06-19 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
US6495721B1 (en) * 1999-08-09 2002-12-17 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride Form II and methods for the preparation thereof
US20050119351A1 (en) * 1999-10-29 2005-06-02 Van Der Schaaf Paul A. Polymorphic forms of sertraline hydrochloride
TWI260315B (en) * 1999-10-29 2006-08-21 Ciba Sc Holding Ag Polymorphic forms of sertraline hydrochloride
US7442838B2 (en) * 1999-10-29 2008-10-28 Ciba Specialty Chemicals Corp. Polymorphic forms of sertraline hydrochloride
SK8872002A3 (en) * 1999-12-21 2002-12-03 Teva Pharma Novel sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and methods of using them
IN187170B (pl) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
IN189886B (pl) * 2000-03-29 2003-05-03 Sun Pharmaceutical Ind Ltd
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
WO2003093217A1 (en) * 2002-04-29 2003-11-13 Teva Pharmaceutical Industries Ltd. Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof
CA2537804A1 (en) * 2003-09-05 2005-03-17 Teva Pharmaceutical Industries Ltd A recycling process for preparing sertraline
ATE469119T1 (de) * 2003-11-04 2010-06-15 Cipla Ltd Verfahren zur herstellung von polymorphen von sertralin hydrochlorid
US20060014838A1 (en) * 2004-07-14 2006-01-19 Sudhakar Valluri Process for converting trans-sertraline to cis-sertraline
EP1858838A1 (en) * 2006-01-23 2007-11-28 Teva Pharmaceutical Industries Ltd. A recycling process for preparing sertraline
US7953216B2 (en) 2007-05-04 2011-05-31 3V Technologies Incorporated Systems and methods for RFID-based access management of electronic devices
US7408082B1 (en) 2007-08-09 2008-08-05 Npil Pharmaceuticals (Uk) Limited Racemisation process
WO2009019412A1 (en) * 2007-08-09 2009-02-12 Npil Pharmaceuticals (Uk) Limited Racemisation process for obtaining (1s,4s) n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine (sertraline)
CN103270020B (zh) * 2010-12-22 2016-01-20 拜耳知识产权有限责任公司 制备顺-1-铵-4-烷氧基环己甲腈盐的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3506714A (en) * 1967-12-22 1970-04-14 Merck & Co Inc Process for the preparation of methyl (3 - lower alkoxy - 4 - hydroxybenzyl)ketones
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
JPS59497B2 (ja) * 1979-11-01 1984-01-07 フアイザ−・インコ−ポレ−テツド トランス−４−フエニル−１，２，３，４−テトラヒドロ−１−ナフタレンアミンの抗抑うつ性誘導体
US4556676A (en) * 1979-11-01 1985-12-03 Pfizer Inc. Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4463176A (en) * 1982-09-13 1984-07-31 Mead Johnson & Company Process for resolution of optical isomers

Also Published As

Publication number Publication date
FI933860L (fi) 1993-09-03
YU48743B (sh) 1999-09-27
HU217064B (hu) 1999-11-29
BR9205727A (pt) 1994-12-27
EP0575507B1 (en) 1996-01-31
PL166756B1 (pl) 1995-06-30
EG20002A (en) 1997-02-27
DE69208080D1 (de) 1996-03-14
CN1064480A (zh) 1992-09-16
CA2105393C (en) 1996-01-02
GR3019040T3 (en) 1996-05-31
PT100189A (pt) 1993-05-31
NO179609C (no) 1996-11-13
CN1040641C (zh) 1998-11-11
US5082970A (en) 1992-01-21
YU22492A (sh) 1994-09-09
ZA921641B (en) 1993-09-06
JP2736167B2 (ja) 1998-04-02
IL101082A0 (en) 1992-11-15
DE69208080T2 (de) 1996-05-30
IE920698A1 (en) 1992-09-09
DK0575507T3 (da) 1996-04-09
JPH06505492A (ja) 1994-06-23
NO179609B (no) 1996-08-05
CA2105393A1 (en) 1992-09-07
FI933860A0 (fi) 1993-09-03
MY106803A (en) 1995-07-31
PT100189B (pt) 1999-06-30
HU9302515D0 (en) 1993-12-28
RU2079483C1 (ru) 1997-05-20
HUT67707A (en) 1995-04-28
NO933141D0 (no) 1993-09-03
CZ285170B6 (cs) 1999-06-16
ES2083741T3 (es) 1996-04-16
FI112074B (fi) 2003-10-31
KR0169750B1 (ko) 1999-03-20
EP0575507A1 (en) 1993-12-29
AU647620B2 (en) 1994-03-24
CZ395692A3 (en) 1993-12-15
MX9200953A (es) 1992-09-01
ATE133655T1 (de) 1996-02-15
NO933141L (no) 1993-09-03
IE70061B1 (en) 1996-10-16
WO1992015552A1 (en) 1992-09-17
NZ241844A (en) 1993-07-27
AU1644592A (en) 1992-10-06

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