IL100484A - Pharmaceutical compositions containing 1H-benz [b] azepine 2,5 dione derivatives some such novel compounds and process for their preparation - Google Patents

Pharmaceutical compositions containing 1H-benz [b] azepine 2,5 dione derivatives some such novel compounds and process for their preparation

Info

Publication number
IL100484A
IL100484A IL10048491A IL10048491A IL100484A IL 100484 A IL100484 A IL 100484A IL 10048491 A IL10048491 A IL 10048491A IL 10048491 A IL10048491 A IL 10048491A IL 100484 A IL100484 A IL 100484A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
azepine
benz
preparation
compositions containing
Prior art date
Application number
IL10048491A
Other languages
English (en)
Other versions
IL100484A0 (en
Original Assignee
Zeneca Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Pharmaceuticals filed Critical Zeneca Pharmaceuticals
Publication of IL100484A0 publication Critical patent/IL100484A0/xx
Publication of IL100484A publication Critical patent/IL100484A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10048491A 1991-01-02 1991-12-24 Pharmaceutical compositions containing 1H-benz [b] azepine 2,5 dione derivatives some such novel compounds and process for their preparation IL100484A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919100028A GB9100028D0 (en) 1991-01-02 1991-01-02 Compounds

Publications (2)

Publication Number Publication Date
IL100484A0 IL100484A0 (en) 1992-09-06
IL100484A true IL100484A (en) 1997-02-18

Family

ID=10687882

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10048491A IL100484A (en) 1991-01-02 1991-12-24 Pharmaceutical compositions containing 1H-benz [b] azepine 2,5 dione derivatives some such novel compounds and process for their preparation

Country Status (22)

Country Link
US (3) US5254683A (de)
EP (1) EP0517876B1 (de)
JP (1) JP3034604B2 (de)
KR (1) KR100229049B1 (de)
AT (1) ATE144423T1 (de)
AU (1) AU650086B2 (de)
CA (1) CA2058593A1 (de)
CZ (1) CZ299292A3 (de)
DE (1) DE69122858T2 (de)
DK (1) DK0517876T3 (de)
ES (1) ES2093246T3 (de)
FI (1) FI104071B (de)
GB (2) GB9100028D0 (de)
GR (1) GR3021440T3 (de)
HU (2) HU212269B (de)
IE (1) IE920009A1 (de)
IL (1) IL100484A (de)
NO (1) NO300497B1 (de)
NZ (1) NZ241197A (de)
PL (1) PL166481B1 (de)
WO (1) WO1992011854A1 (de)
ZA (1) ZA9223B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9100028D0 (en) * 1991-01-02 1991-02-20 Ici Plc Compounds
GB9212308D0 (en) * 1992-06-10 1992-07-22 Ici Plc Therapeutic compositions
EP0647137B1 (de) * 1992-06-22 2008-08-13 The Regents Of The University Of California Glycinrezeptorantagonisten und ihre verwendung
CA2115792C (en) 1993-03-05 2005-11-01 David J. Mayer Method for the treatment of pain
US5834479A (en) * 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
GB9311948D0 (en) * 1993-06-10 1993-07-28 Zeneca Ltd Substituted nitrogen heterocycles
US5801168A (en) * 1994-06-09 1998-09-01 Zeneca Limited Substituted nitrogen heterocycles
US5476933A (en) * 1994-11-16 1995-12-19 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Azepine synthesis via a diels-alder reaction
JP4989830B2 (ja) * 1999-07-21 2012-08-01 サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク 脳によるグルタミン酸塩の放出に対して抑制効果を示す薬剤を製造するためのベータ−ナフトキノン誘導体の使用
FR2796552A1 (fr) 1999-07-21 2001-01-26 Centre Nat Rech Scient Nouvelle utilisation de derives de la beta-naphtoquinone et de leurs sels pour la fabrication de medicaments exercant un effet inhibiteur sur la liberation de glutamate dans le cerveau
WO2016199789A1 (ja) * 2015-06-08 2016-12-15 国立大学法人名古屋大学 トリフルオロメチル置換セミスクアレートの製造方法、トリフルオロメチル置換セミスクアレートを起点とするトリフルオロメチル化合物の製造方法及びトリフルオロメチル基含有化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1340334A (en) * 1970-07-06 1973-12-12 Rees A H Synthesis of benzazetropolones and hence of kynurenic acids
CY1403A (en) * 1981-08-11 1987-12-18 Ciba Geigy Ag Benzazepin-2-ones
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4473575A (en) * 1982-07-19 1984-09-25 Ciba-Geigy Corporation 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
US4575503A (en) * 1983-02-10 1986-03-11 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4477446A (en) * 1983-07-01 1984-10-16 Usv Pharmaceutical Corporation 1-Benzazepines and their pharmaceutical uses
DE3416695A1 (de) * 1984-05-05 1985-11-07 Bayer Ag, 5090 Leverkusen Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
EP0450097B1 (de) * 1989-10-20 1996-04-24 Otsuka Pharmaceutical Co., Ltd. Benzoheterozyklische verbindungen
GB9100028D0 (en) * 1991-01-02 1991-02-20 Ici Plc Compounds
EP0647137B1 (de) * 1992-06-22 2008-08-13 The Regents Of The University Of California Glycinrezeptorantagonisten und ihre verwendung

Also Published As

Publication number Publication date
IE920009A1 (en) 1992-07-15
GB2251616A (en) 1992-07-15
GB9100028D0 (en) 1991-02-20
HU9202618D0 (en) 1992-10-28
DE69122858D1 (de) 1996-11-28
PL166481B1 (en) 1995-05-31
PL295932A1 (en) 1993-10-04
ATE144423T1 (de) 1996-11-15
KR100229049B1 (ko) 1999-11-01
US5254683A (en) 1993-10-19
NO300497B1 (no) 1997-06-09
CA2058593A1 (en) 1992-07-03
JP3034604B2 (ja) 2000-04-17
DK0517876T3 (da) 1997-04-01
NZ241197A (en) 1994-10-26
HUT64309A (en) 1993-12-28
ZA9223B (en) 1992-09-30
US5541319A (en) 1996-07-30
FI104071B1 (fi) 1999-11-15
WO1992011854A1 (en) 1992-07-23
FI923759A (fi) 1992-08-20
GR3021440T3 (en) 1997-01-31
EP0517876A1 (de) 1992-12-16
AU9134091A (en) 1992-08-17
US5446039A (en) 1995-08-29
DE69122858T2 (de) 1997-02-20
FI104071B (fi) 1999-11-15
CZ299292A3 (en) 1993-01-13
NO923413L (no) 1992-09-01
GB9127498D0 (en) 1992-02-19
GB2251616B (en) 1995-01-11
HU211466A9 (en) 1995-11-28
HU212269B (en) 1996-07-29
NO923413D0 (no) 1992-09-01
ES2093246T3 (es) 1996-12-16
FI923759A0 (fi) 1992-08-20
IL100484A0 (en) 1992-09-06
JPH07502007A (ja) 1995-03-02
EP0517876B1 (de) 1996-10-23
AU650086B2 (en) 1994-06-09

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees