IL100233A - Medicinal preparations containing esters of castanospermine with anti-herpes activity - Google Patents

Medicinal preparations containing esters of castanospermine with anti-herpes activity

Info

Publication number
IL100233A
IL100233A IL10023391A IL10023391A IL100233A IL 100233 A IL100233 A IL 100233A IL 10023391 A IL10023391 A IL 10023391A IL 10023391 A IL10023391 A IL 10023391A IL 100233 A IL100233 A IL 100233A
Authority
IL
Israel
Prior art keywords
halogen
octahydro
hydrogen
castanospermine
indolizinetetrol
Prior art date
Application number
IL10023391A
Other languages
English (en)
Hebrew (he)
Other versions
IL100233A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL100233A0 publication Critical patent/IL100233A0/xx
Publication of IL100233A publication Critical patent/IL100233A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
IL10023391A 1990-12-18 1991-12-03 Medicinal preparations containing esters of castanospermine with anti-herpes activity IL100233A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027433A GB9027433D0 (en) 1990-12-18 1990-12-18 Anti-herpes castanospermine esters

Publications (2)

Publication Number Publication Date
IL100233A0 IL100233A0 (en) 1992-09-06
IL100233A true IL100233A (en) 1996-03-31

Family

ID=10687190

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10023391A IL100233A (en) 1990-12-18 1991-12-03 Medicinal preparations containing esters of castanospermine with anti-herpes activity

Country Status (20)

Country Link
US (1) US5385911A (hu)
EP (1) EP0492841B1 (hu)
JP (1) JPH04342587A (hu)
KR (1) KR100192642B1 (hu)
AT (1) ATE126435T1 (hu)
AU (1) AU643098B2 (hu)
CA (1) CA2057821A1 (hu)
DE (1) DE69112192T2 (hu)
DK (1) DK0492841T3 (hu)
ES (1) ES2078462T3 (hu)
FI (1) FI915929A (hu)
GB (1) GB9027433D0 (hu)
GR (1) GR3017152T3 (hu)
HU (1) HU210257B (hu)
IE (1) IE914400A1 (hu)
IL (1) IL100233A (hu)
NO (1) NO914986D0 (hu)
NZ (1) NZ240976A (hu)
PT (1) PT99835B (hu)
ZA (1) ZA919808B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466714A (en) * 1987-12-31 1995-11-14 Research Foundation For Mental Health Hygiene, Inc. Spermicidal and cytocidal fatty acid compositions
US5959111A (en) * 1997-05-22 1999-09-28 Hoechst Marion Roussel, Inc. Process for preparing 6-0-monoesters of castanospermine
WO2001054692A1 (en) * 2000-01-28 2001-08-02 Synergy Pharmaceuticals, Inc. Use of castanospermine and substituted-castanospermine compounds for treating hepatitis virus infections
GB0110832D0 (en) * 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
GB0116643D0 (en) * 2001-07-09 2001-08-29 Virogen Ltd Antiviral compounds
US7930711B2 (en) * 2003-03-06 2011-04-19 Wegener Communications, Inc. Apparatus and method for addressing control in a network for distributed data
JP2008515816A (ja) * 2004-10-06 2008-05-15 ミジェニックス インコーポレイテッド カスタノスペルミンを含有する、併用抗ウイルス組成物およびその使用方法
US20060078580A1 (en) * 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US7740875B2 (en) * 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
CN102727437A (zh) * 2006-08-02 2012-10-17 牛津大学院长校长专家委员会 病毒感染的脂质体治疗
WO2009118658A2 (en) * 2008-03-26 2009-10-01 University Of Oxford Endoplasmic reticulum targeting liposomes
WO2010109330A2 (en) * 2009-03-27 2010-09-30 University Of Oxford Cholesterol level lowering liposomes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760079A (en) * 1983-01-10 1988-07-26 Baltech, Inc. Treatment of diseases caused by herpes viruses
US4628063A (en) * 1984-03-08 1986-12-09 Dana P. Brigham Antiviral pharmaceutical preparations and methods for their use
US4782065A (en) * 1984-04-18 1988-11-01 Board Of Regents, The University Of Texas System Methods and compositions for treating viral infections
US4800081A (en) * 1984-04-18 1989-01-24 Board Of Regents, The University Of Texas System Methods and compositions for treating viral infections
JPS61227566A (ja) * 1985-04-01 1986-10-09 Fujisawa Pharmaceut Co Ltd スワインソニンおよび関連化合物の合成法
US4751236A (en) * 1987-05-20 1988-06-14 Avihou Mishniot Method for treating genital herpes
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US5017563A (en) * 1988-06-23 1991-05-21 Merrell Dow Pharmaceuticals Inc. Castanospermine esters and glycosides

Also Published As

Publication number Publication date
DE69112192D1 (de) 1995-09-21
HUT59924A (en) 1992-07-28
US5385911A (en) 1995-01-31
EP0492841B1 (en) 1995-08-16
AU8964191A (en) 1992-06-25
IE914400A1 (en) 1992-07-01
FI915929A (fi) 1992-06-19
JPH04342587A (ja) 1992-11-30
NO914986D0 (no) 1991-12-17
DK0492841T3 (da) 1995-09-18
EP0492841A1 (en) 1992-07-01
GR3017152T3 (en) 1995-11-30
CA2057821A1 (en) 1992-06-19
HU913989D0 (en) 1992-03-30
DE69112192T2 (de) 1996-04-04
HU210257B (en) 1995-03-28
ATE126435T1 (de) 1995-09-15
KR100192642B1 (ko) 1999-06-15
GB9027433D0 (en) 1991-02-06
AU643098B2 (en) 1993-11-04
FI915929A0 (fi) 1991-12-17
NZ240976A (en) 1997-03-24
PT99835B (pt) 1999-06-30
KR920011488A (ko) 1992-07-24
ZA919808B (en) 1992-09-30
ES2078462T3 (es) 1995-12-16
IL100233A0 (en) 1992-09-06
PT99835A (pt) 1992-12-31

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees