IL100119A0 - Optically-active thiazoloisoindolinone derivatives with antiviral action - Google Patents
Optically-active thiazoloisoindolinone derivatives with antiviral actionInfo
- Publication number
- IL100119A0 IL100119A0 IL100119A IL10011991A IL100119A0 IL 100119 A0 IL100119 A0 IL 100119A0 IL 100119 A IL100119 A IL 100119A IL 10011991 A IL10011991 A IL 10011991A IL 100119 A0 IL100119 A0 IL 100119A0
- Authority
- IL
- Israel
- Prior art keywords
- optically
- thiazoloisoindolinone
- derivatives
- active
- antiviral action
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
The present invention relates to optically active thiazoloisoindolinones of general formulae (I) and (II) where: R is a hydrogen atom or a straight-chained or branched, saturated or unsaturated aliphatic radical with 1-7 carbon atoms which may also be substituted by phenyl, or a phenyl ring which may be singly or multiply substituted by C1-C4-alkyl, C1-C4-alkoxy, hydroxy, trifluoromethyl, C1-C4-alkyl sulphonyl or a halogen; n is 0, 1 or 2; and their pharmacologically acceptable salts and tautomers. The object of the invention also includes medicaments containing the compounds of formula (I) or (II) and their use for the production of medicaments to treat viral or retroviral infections.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4037674A DE4037674A1 (en) | 1990-11-27 | 1990-11-27 | New 2,3-di:hydro:thiazolo:isoindolone derivs. |
DE19914122418 DE4122418A1 (en) | 1991-07-06 | 1991-07-06 | Optically active thiazolo:isoindolinone derivs. - are antiviral agents, effective against diseases caused by DNA and by RNA viruses, and by retrovirus(es), esp. HIV |
Publications (1)
Publication Number | Publication Date |
---|---|
IL100119A0 true IL100119A0 (en) | 1992-08-18 |
Family
ID=25898790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL100119A IL100119A0 (en) | 1990-11-27 | 1991-11-21 | Optically-active thiazoloisoindolinone derivatives with antiviral action |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0559815B1 (en) |
JP (1) | JPH06502634A (en) |
CN (1) | CN1062732A (en) |
AT (1) | ATE127467T1 (en) |
AU (1) | AU8910491A (en) |
CA (1) | CA2095255A1 (en) |
DE (1) | DE59106440D1 (en) |
ES (1) | ES2079850T3 (en) |
IE (1) | IE914100A1 (en) |
IL (1) | IL100119A0 (en) |
PT (1) | PT99609A (en) |
WO (1) | WO1992009606A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4129779A1 (en) * | 1991-09-07 | 1993-03-11 | Boehringer Mannheim Gmbh | NEW TRICYCLIC THIAZOLE AND OXAZOLE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM |
WO2002066479A1 (en) * | 2001-02-23 | 2002-08-29 | Banyu Pharmaceutical Co.,Ltd. | Novel isoindole derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH433321A (en) * | 1964-02-11 | 1967-04-15 | Geigy Ag J R | Process for the preparation of new, condensed heterocyclic compounds |
CH469733A (en) * | 1965-07-27 | 1969-03-15 | Geigy Ag J R | Process for the preparation of new, condensed heterocyclic compounds |
-
1991
- 1991-11-21 IL IL100119A patent/IL100119A0/en unknown
- 1991-11-22 AT AT92902580T patent/ATE127467T1/en not_active IP Right Cessation
- 1991-11-22 JP JP4500305A patent/JPH06502634A/en active Pending
- 1991-11-22 CA CA002095255A patent/CA2095255A1/en not_active Abandoned
- 1991-11-22 ES ES92902580T patent/ES2079850T3/en not_active Expired - Lifetime
- 1991-11-22 DE DE59106440T patent/DE59106440D1/en not_active Expired - Fee Related
- 1991-11-22 WO PCT/EP1991/002205 patent/WO1992009606A1/en active IP Right Grant
- 1991-11-22 AU AU89104/91A patent/AU8910491A/en not_active Abandoned
- 1991-11-22 EP EP92902580A patent/EP0559815B1/en not_active Expired - Lifetime
- 1991-11-26 PT PT99609A patent/PT99609A/en not_active Application Discontinuation
- 1991-11-26 IE IE410091A patent/IE914100A1/en unknown
- 1991-11-27 CN CN91111914A patent/CN1062732A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JPH06502634A (en) | 1994-03-24 |
EP0559815A1 (en) | 1993-09-15 |
ES2079850T3 (en) | 1996-01-16 |
IE914100A1 (en) | 1992-06-03 |
PT99609A (en) | 1992-10-30 |
WO1992009606A1 (en) | 1992-06-11 |
CA2095255A1 (en) | 1992-05-28 |
CN1062732A (en) | 1992-07-15 |
EP0559815B1 (en) | 1995-09-06 |
ATE127467T1 (en) | 1995-09-15 |
DE59106440D1 (en) | 1995-10-12 |
AU8910491A (en) | 1992-06-25 |
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