AU8910491A - Optically active thiazoloisoindolinone derivatives with an antiviral action - Google Patents

Optically active thiazoloisoindolinone derivatives with an antiviral action

Info

Publication number
AU8910491A
AU8910491A AU89104/91A AU8910491A AU8910491A AU 8910491 A AU8910491 A AU 8910491A AU 89104/91 A AU89104/91 A AU 89104/91A AU 8910491 A AU8910491 A AU 8910491A AU 8910491 A AU8910491 A AU 8910491A
Authority
AU
Australia
Prior art keywords
optically active
thiazoloisoindolinone
derivatives
antiviral action
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU89104/91A
Inventor
Bernhard Konig
Herbert Leinert
Ulrike Leser
Alfred Mertens
Hans Seidel
Harald Zilch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4037674A external-priority patent/DE4037674A1/en
Priority claimed from DE19914122418 external-priority patent/DE4122418A1/en
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU8910491A publication Critical patent/AU8910491A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The present invention relates to optically active thiazoloisoindolinones of general formulae (I) and (II) where: R is a hydrogen atom or a straight-chained or branched, saturated or unsaturated aliphatic radical with 1-7 carbon atoms which may also be substituted by phenyl, or a phenyl ring which may be singly or multiply substituted by C1-C4-alkyl, C1-C4-alkoxy, hydroxy, trifluoromethyl, C1-C4-alkyl sulphonyl or a halogen; n is 0, 1 or 2; and their pharmacologically acceptable salts and tautomers. The object of the invention also includes medicaments containing the compounds of formula (I) or (II) and their use for the production of medicaments to treat viral or retroviral infections.
AU89104/91A 1990-11-27 1991-11-22 Optically active thiazoloisoindolinone derivatives with an antiviral action Abandoned AU8910491A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4037674A DE4037674A1 (en) 1990-11-27 1990-11-27 New 2,3-di:hydro:thiazolo:isoindolone derivs.
DE4037674 1990-11-27
DE4122418 1991-07-06
DE19914122418 DE4122418A1 (en) 1991-07-06 1991-07-06 Optically active thiazolo:isoindolinone derivs. - are antiviral agents, effective against diseases caused by DNA and by RNA viruses, and by retrovirus(es), esp. HIV

Publications (1)

Publication Number Publication Date
AU8910491A true AU8910491A (en) 1992-06-25

Family

ID=25898790

Family Applications (1)

Application Number Title Priority Date Filing Date
AU89104/91A Abandoned AU8910491A (en) 1990-11-27 1991-11-22 Optically active thiazoloisoindolinone derivatives with an antiviral action

Country Status (12)

Country Link
EP (1) EP0559815B1 (en)
JP (1) JPH06502634A (en)
CN (1) CN1062732A (en)
AT (1) ATE127467T1 (en)
AU (1) AU8910491A (en)
CA (1) CA2095255A1 (en)
DE (1) DE59106440D1 (en)
ES (1) ES2079850T3 (en)
IE (1) IE914100A1 (en)
IL (1) IL100119A0 (en)
PT (1) PT99609A (en)
WO (1) WO1992009606A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4129779A1 (en) * 1991-09-07 1993-03-11 Boehringer Mannheim Gmbh NEW TRICYCLIC THIAZOLE AND OXAZOLE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM
WO2002066479A1 (en) * 2001-02-23 2002-08-29 Banyu Pharmaceutical Co.,Ltd. Novel isoindole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH433321A (en) * 1964-02-11 1967-04-15 Geigy Ag J R Process for the preparation of new, condensed heterocyclic compounds
CH469733A (en) * 1965-07-27 1969-03-15 Geigy Ag J R Process for the preparation of new, condensed heterocyclic compounds

Also Published As

Publication number Publication date
EP0559815A1 (en) 1993-09-15
ATE127467T1 (en) 1995-09-15
IL100119A0 (en) 1992-08-18
PT99609A (en) 1992-10-30
CN1062732A (en) 1992-07-15
WO1992009606A1 (en) 1992-06-11
ES2079850T3 (en) 1996-01-16
JPH06502634A (en) 1994-03-24
IE914100A1 (en) 1992-06-03
EP0559815B1 (en) 1995-09-06
CA2095255A1 (en) 1992-05-28
DE59106440D1 (en) 1995-10-12

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