IE920940A1 - Organosulphur compounds useful for the treatment of glaucoma - Google Patents

Organosulphur compounds useful for the treatment of glaucoma

Info

Publication number
IE920940A1
IE920940A1 IE094092A IE920940A IE920940A1 IE 920940 A1 IE920940 A1 IE 920940A1 IE 094092 A IE094092 A IE 094092A IE 920940 A IE920940 A IE 920940A IE 920940 A1 IE920940 A1 IE 920940A1
Authority
IE
Ireland
Prior art keywords
compound
derivative
acm
salt
cys
Prior art date
Application number
IE094092A
Other languages
English (en)
Inventor
Kailash Kumar Gauri
Stig Aasmul-Olsen
Fred Widmer
Original Assignee
Carlbiotech Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlbiotech Ltd As filed Critical Carlbiotech Ltd As
Publication of IE920940A1 publication Critical patent/IE920940A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IE094092A 1991-03-25 1992-03-25 Organosulphur compounds useful for the treatment of glaucoma IE920940A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK91531A DK53191D0 (da) 1991-03-25 1991-03-25 Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse

Publications (1)

Publication Number Publication Date
IE920940A1 true IE920940A1 (en) 1992-10-07

Family

ID=8094601

Family Applications (1)

Application Number Title Priority Date Filing Date
IE094092A IE920940A1 (en) 1991-03-25 1992-03-25 Organosulphur compounds useful for the treatment of glaucoma

Country Status (7)

Country Link
EP (1) EP0577690A1 (ja)
JP (1) JPH06505988A (ja)
AU (1) AU1455992A (ja)
CA (1) CA2106860A1 (ja)
DK (1) DK53191D0 (ja)
IE (1) IE920940A1 (ja)
WO (1) WO1992016550A1 (ja)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2261926C3 (de) * 1972-12-18 1978-11-30 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Verfahren zur Herstellung von DL-Methionyl-DL-methionin
US4024286A (en) * 1976-05-17 1977-05-17 Miles Laboratories, Inc. Fortification of foodstuffs with C-terminal amino acid substituted methionine dipeptides
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
IE58407B1 (en) * 1984-04-13 1993-09-22 Akzo Nv Peptides
US4885293A (en) * 1984-09-24 1989-12-05 Schering Corporation Antiglaucoma agents
US4585587A (en) * 1984-10-19 1986-04-29 Northwestern University Antigenic peptide compounds
GB8430255D0 (en) * 1984-11-30 1985-01-09 Erba Farmitalia Biologically active oligopeptides
ES2039402T3 (es) * 1986-10-24 1993-10-01 Pfrimmer Kabi Gmbh & Co. Kg Empleo de peptidos n,n'-bis-l-aminoacido-l-cistina en preparados de aminoacidos para alimentacion oral y parenteral.
GB8626539D0 (en) * 1986-11-06 1986-12-10 Nycomed As Peptide compounds
DK72587D0 (da) * 1987-02-13 1987-02-13 Carlsberg Biotechnology Ltd Fremgangsmaade til enzymatisk fremstilling af dipeptider
DK163435C (da) * 1988-08-12 1992-07-20 Carlsberg Biotechnology Ltd Fremgangsmaade til enzymatisk fremstilling af dipeptider og derivater deraf
US5102871A (en) * 1989-04-24 1992-04-07 Kyowa Hakko Kogyo Co., Ltd. Nutrient composition
DK167813B1 (da) * 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
HU206372B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
DK53191D0 (da) 1991-03-25
JPH06505988A (ja) 1994-07-07
CA2106860A1 (en) 1992-09-26
WO1992016550A1 (en) 1992-10-01
EP0577690A1 (en) 1994-01-12
AU1455992A (en) 1992-10-21

Similar Documents

Publication Publication Date Title
US5411942A (en) Peptide derivative, pharmaceutical preparation containing it and method for treatment of glaucoma
US6232468B1 (en) Dipeptides with neurokinin-antagonistic activity
US5700827A (en) Amino acid derivatives, processes for the manufacture thereof and pharmaceutical compositions (II) containing these compounds
US6147051A (en) Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction
JP4310588B2 (ja) 新規ペプチドおよびその医薬用途
JP2000507617A (ja) ヘプタペプチドオキシトシン類似体
US20170166609A1 (en) Peptides for promoting angiogenesis and use thereof
WO1994005693A1 (de) Neue aminosäurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen
AU673431B2 (en) Motilin-like polypeptides that inhibit gastrointestinal motor activity
US5464821A (en) Small peptidic compounds useful for the treatment of glaucoma
ES2268730T3 (es) Composiciones farmacologicas oftalmicas.
AU677324B2 (en) Motilin-like polypeptides with gastrointestinal motor stimulating activity
IE920940A1 (en) Organosulphur compounds useful for the treatment of glaucoma
JP2003231695A (ja) 新規ペプチドおよびその医薬用途
AU636427C (en) Peptide derivative, process for the preparation thereof, pharmaceutical preparation containing it and method for treatment of glaucoma
JPH10130163A (ja) アルツハイマー病の治療および予防用医薬の製造のためのブラジキニン拮抗薬の使用
WO2002009739A1 (en) Treatment of ocular disorders with somatostatin analogues
HUT62012A (en) Process for producing acid amides and peptides
HUT62915A (en) Process for producing amino acid derivatives and pharmaceutical compositions comprising same as active ingredient

Legal Events

Date Code Title Description
FC9A Application refused sect. 31(1)