IE782481L - Thioalkanoylalkanoic acid compounds - Google Patents
Thioalkanoylalkanoic acid compoundsInfo
- Publication number
- IE782481L IE782481L IE782481A IE248178A IE782481L IE 782481 L IE782481 L IE 782481L IE 782481 A IE782481 A IE 782481A IE 248178 A IE248178 A IE 248178A IE 782481 L IE782481 L IE 782481L
- Authority
- IE
- Ireland
- Prior art keywords
- thioalkanoylalkanoic
- acid compounds
- hydrogen
- image
- gb2017081a
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/53—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Abstract
Thioalkanoylalkanoic acid compounds and salts thereof having the formula <IMAGE> wherein R1, R2, R3 and R4 each is hydrogen or lower alkyl; R5 is hydrogen, lower alkanoyl, benzoyl or <IMAGE> A and B each is hydrogen or join together as a polymethylene chain -(CH2)n- to complete a 4-, 5- or 6- membered cycloalkyl group, and m is 0 or 1, are angiotensin converting enzyme inhibitors and are useful as hypotensive agents.
[GB2017081A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89044678A | 1978-03-27 | 1978-03-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE782481L true IE782481L (en) | 1979-09-27 |
IE48041B1 IE48041B1 (en) | 1984-09-05 |
Family
ID=25396691
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE2481/78A IE48041B1 (en) | 1978-03-27 | 1978-12-15 | Thioalkanoylalkanoic acid compounds |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS54128516A (en) |
AU (1) | AU522896B2 (en) |
BE (1) | BE873219A (en) |
CA (1) | CA1125783A (en) |
CH (1) | CH646421A5 (en) |
DE (1) | DE2855835A1 (en) |
DK (1) | DK586778A (en) |
FR (2) | FR2435467A1 (en) |
GB (1) | GB2017081B (en) |
IE (1) | IE48041B1 (en) |
IT (1) | IT1110882B (en) |
LU (1) | LU80731A1 (en) |
NL (1) | NL7812598A (en) |
NO (1) | NO784398L (en) |
SE (1) | SE7813279L (en) |
ZA (1) | ZA786929B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235885A (en) * | 1979-06-25 | 1980-11-25 | E. R. Squibb & Sons, Inc. | Inhibitors of mammalian collagenase |
FR2605630B1 (en) * | 1986-10-22 | 1989-06-30 | Roussel Uclaf | PROCESS FOR THE PREPARATION OF OCTAHYDROINDOLE DERIVATIVES AND PREPARATION INTERMEDIATES |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB762575A (en) * | 1952-04-24 | 1956-11-28 | American Cyanamid Co | Omega [3-(1,2-dithiolanyl)] aliphatic acids, salts and esters and the preparation thereof |
US2828321A (en) * | 1953-10-19 | 1958-03-25 | American Cyanamid Co | Keto aliphatic acid esters and method of preparing the same |
-
1978
- 1978-12-08 CA CA317,663A patent/CA1125783A/en not_active Expired
- 1978-12-11 ZA ZA00786929A patent/ZA786929B/en unknown
- 1978-12-15 IE IE2481/78A patent/IE48041B1/en unknown
- 1978-12-15 AU AU42604/78A patent/AU522896B2/en not_active Expired
- 1978-12-21 CH CH1302878A patent/CH646421A5/en not_active IP Right Cessation
- 1978-12-22 DE DE19782855835 patent/DE2855835A1/en not_active Ceased
- 1978-12-22 GB GB7849941A patent/GB2017081B/en not_active Expired
- 1978-12-22 SE SE7813279A patent/SE7813279L/en not_active Application Discontinuation
- 1978-12-27 JP JP16450578A patent/JPS54128516A/en active Pending
- 1978-12-28 NO NO784398A patent/NO784398L/en unknown
- 1978-12-28 NL NL7812598A patent/NL7812598A/en not_active Application Discontinuation
- 1978-12-28 FR FR7836793A patent/FR2435467A1/en active Granted
- 1978-12-28 IT IT52478/78A patent/IT1110882B/en active
- 1978-12-28 LU LU80731A patent/LU80731A1/en unknown
- 1978-12-29 DK DK586778A patent/DK586778A/en unknown
- 1978-12-29 BE BE192684A patent/BE873219A/en not_active IP Right Cessation
-
1979
- 1979-04-02 FR FR7908240A patent/FR2421165A1/en active Granted
Also Published As
Publication number | Publication date |
---|---|
GB2017081B (en) | 1982-07-28 |
AU4260478A (en) | 1979-10-04 |
GB2017081A (en) | 1979-10-03 |
IE48041B1 (en) | 1984-09-05 |
FR2435467B1 (en) | 1983-08-19 |
FR2421165A1 (en) | 1979-10-26 |
IT7852478A0 (en) | 1978-12-28 |
BE873219A (en) | 1979-06-29 |
SE7813279L (en) | 1979-09-28 |
AU522896B2 (en) | 1982-07-01 |
ZA786929B (en) | 1979-12-27 |
DK586778A (en) | 1979-09-28 |
FR2435467A1 (en) | 1980-04-04 |
CA1125783A (en) | 1982-06-15 |
JPS54128516A (en) | 1979-10-05 |
FR2421165B1 (en) | 1982-02-19 |
IT1110882B (en) | 1986-01-06 |
DE2855835A1 (en) | 1979-10-04 |
NO784398L (en) | 1979-09-28 |
NL7812598A (en) | 1979-10-01 |
CH646421A5 (en) | 1984-11-30 |
LU80731A1 (en) | 1979-04-13 |
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