FR2435467A1 - THIOALCANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE - Google Patents

THIOALCANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE

Info

Publication number
FR2435467A1
FR2435467A1 FR7836793A FR7836793A FR2435467A1 FR 2435467 A1 FR2435467 A1 FR 2435467A1 FR 7836793 A FR7836793 A FR 7836793A FR 7836793 A FR7836793 A FR 7836793A FR 2435467 A1 FR2435467 A1 FR 2435467A1
Authority
FR
France
Prior art keywords
acid derivatives
thioalcanoylalcanoic
therapeutic use
thioalkanoylalkanoic
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7836793A
Other languages
French (fr)
Other versions
FR2435467B1 (en
Inventor
Miguel Angel Ondetti
Michael Edward Condon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2435467A1 publication Critical patent/FR2435467A1/en
Application granted granted Critical
Publication of FR2435467B1 publication Critical patent/FR2435467B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/53—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Abstract

L'invention concerne des dérivés d'acide thioalcanoylalcanoïque et leurs sels de formule :The invention relates to thioalkanoylalkanoic acid derivatives and their salts of formula:

FR7836793A 1978-03-27 1978-12-28 THIOALCANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE Granted FR2435467A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89044678A 1978-03-27 1978-03-27

Publications (2)

Publication Number Publication Date
FR2435467A1 true FR2435467A1 (en) 1980-04-04
FR2435467B1 FR2435467B1 (en) 1983-08-19

Family

ID=25396691

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7836793A Granted FR2435467A1 (en) 1978-03-27 1978-12-28 THIOALCANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE
FR7908240A Granted FR2421165A1 (en) 1978-03-27 1979-04-02 1-OXO-2-ALCENYL-CYCLOALCANECARBOXYLIC ACIDS

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7908240A Granted FR2421165A1 (en) 1978-03-27 1979-04-02 1-OXO-2-ALCENYL-CYCLOALCANECARBOXYLIC ACIDS

Country Status (16)

Country Link
JP (1) JPS54128516A (en)
AU (1) AU522896B2 (en)
BE (1) BE873219A (en)
CA (1) CA1125783A (en)
CH (1) CH646421A5 (en)
DE (1) DE2855835A1 (en)
DK (1) DK586778A (en)
FR (2) FR2435467A1 (en)
GB (1) GB2017081B (en)
IE (1) IE48041B1 (en)
IT (1) IT1110882B (en)
LU (1) LU80731A1 (en)
NL (1) NL7812598A (en)
NO (1) NO784398L (en)
SE (1) SE7813279L (en)
ZA (1) ZA786929B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235885A (en) * 1979-06-25 1980-11-25 E. R. Squibb & Sons, Inc. Inhibitors of mammalian collagenase
FR2605630B1 (en) * 1986-10-22 1989-06-30 Roussel Uclaf PROCESS FOR THE PREPARATION OF OCTAHYDROINDOLE DERIVATIVES AND PREPARATION INTERMEDIATES

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2828321A (en) * 1953-10-19 1958-03-25 American Cyanamid Co Keto aliphatic acid esters and method of preparing the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB762575A (en) * 1952-04-24 1956-11-28 American Cyanamid Co Omega [3-(1,2-dithiolanyl)] aliphatic acids, salts and esters and the preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2828321A (en) * 1953-10-19 1958-03-25 American Cyanamid Co Keto aliphatic acid esters and method of preparing the same

Also Published As

Publication number Publication date
IT1110882B (en) 1986-01-06
NO784398L (en) 1979-09-28
FR2435467B1 (en) 1983-08-19
DK586778A (en) 1979-09-28
AU522896B2 (en) 1982-07-01
GB2017081A (en) 1979-10-03
IE48041B1 (en) 1984-09-05
JPS54128516A (en) 1979-10-05
DE2855835A1 (en) 1979-10-04
ZA786929B (en) 1979-12-27
SE7813279L (en) 1979-09-28
IT7852478A0 (en) 1978-12-28
LU80731A1 (en) 1979-04-13
CA1125783A (en) 1982-06-15
AU4260478A (en) 1979-10-04
CH646421A5 (en) 1984-11-30
FR2421165A1 (en) 1979-10-26
GB2017081B (en) 1982-07-28
BE873219A (en) 1979-06-29
NL7812598A (en) 1979-10-01
IE782481L (en) 1979-09-27
FR2421165B1 (en) 1982-02-19

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ST Notification of lapse