LU80731A1 - THIOALKANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE - Google Patents

THIOALKANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE

Info

Publication number
LU80731A1
LU80731A1 LU80731A LU80731A LU80731A1 LU 80731 A1 LU80731 A1 LU 80731A1 LU 80731 A LU80731 A LU 80731A LU 80731 A LU80731 A LU 80731A LU 80731 A1 LU80731 A1 LU 80731A1
Authority
LU
Luxembourg
Prior art keywords
thioalkanoylalcanoic
acid derivatives
therapeutic use
therapeutic
derivatives
Prior art date
Application number
LU80731A
Other languages
French (fr)
Inventor
M Condon
M Ondetti
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of LU80731A1 publication Critical patent/LU80731A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/53—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
LU80731A 1978-03-27 1978-12-28 THIOALKANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE LU80731A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89044678A 1978-03-27 1978-03-27

Publications (1)

Publication Number Publication Date
LU80731A1 true LU80731A1 (en) 1979-04-13

Family

ID=25396691

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80731A LU80731A1 (en) 1978-03-27 1978-12-28 THIOALKANOYLALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE

Country Status (16)

Country Link
JP (1) JPS54128516A (en)
AU (1) AU522896B2 (en)
BE (1) BE873219A (en)
CA (1) CA1125783A (en)
CH (1) CH646421A5 (en)
DE (1) DE2855835A1 (en)
DK (1) DK586778A (en)
FR (2) FR2435467A1 (en)
GB (1) GB2017081B (en)
IE (1) IE48041B1 (en)
IT (1) IT1110882B (en)
LU (1) LU80731A1 (en)
NL (1) NL7812598A (en)
NO (1) NO784398L (en)
SE (1) SE7813279L (en)
ZA (1) ZA786929B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021766A2 (en) * 1979-06-25 1981-01-07 E.R. Squibb & Sons, Inc. Inhibitors of mammalian collagenase

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2605630B1 (en) * 1986-10-22 1989-06-30 Roussel Uclaf PROCESS FOR THE PREPARATION OF OCTAHYDROINDOLE DERIVATIVES AND PREPARATION INTERMEDIATES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB762575A (en) * 1952-04-24 1956-11-28 American Cyanamid Co Omega [3-(1,2-dithiolanyl)] aliphatic acids, salts and esters and the preparation thereof
US2828321A (en) * 1953-10-19 1958-03-25 American Cyanamid Co Keto aliphatic acid esters and method of preparing the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021766A2 (en) * 1979-06-25 1981-01-07 E.R. Squibb & Sons, Inc. Inhibitors of mammalian collagenase
EP0021766A3 (en) * 1979-06-25 1981-05-13 E.R. Squibb & Sons, Inc. E.R. Squibb & Sons, Inc. Inhibitors of mammalian collagenase inhibitors of mammalian collagenase

Also Published As

Publication number Publication date
JPS54128516A (en) 1979-10-05
ZA786929B (en) 1979-12-27
IT7852478A0 (en) 1978-12-28
CA1125783A (en) 1982-06-15
FR2421165B1 (en) 1982-02-19
GB2017081A (en) 1979-10-03
IE48041B1 (en) 1984-09-05
FR2435467B1 (en) 1983-08-19
FR2421165A1 (en) 1979-10-26
IT1110882B (en) 1986-01-06
DE2855835A1 (en) 1979-10-04
NO784398L (en) 1979-09-28
AU522896B2 (en) 1982-07-01
BE873219A (en) 1979-06-29
DK586778A (en) 1979-09-28
SE7813279L (en) 1979-09-28
GB2017081B (en) 1982-07-28
AU4260478A (en) 1979-10-04
FR2435467A1 (en) 1980-04-04
CH646421A5 (en) 1984-11-30
NL7812598A (en) 1979-10-01
IE782481L (en) 1979-09-27

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