IE54065B1 - 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl-)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments - Google Patents

1-(3-(6-fluoro-1,2-benzisoxazol-3-yl-)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments

Info

Publication number
IE54065B1
IE54065B1 IE2558/82A IE255882A IE54065B1 IE 54065 B1 IE54065 B1 IE 54065B1 IE 2558/82 A IE2558/82 A IE 2558/82A IE 255882 A IE255882 A IE 255882A IE 54065 B1 IE54065 B1 IE 54065B1
Authority
IE
Ireland
Prior art keywords
compound
formula
fluoro
benzisoxazol
pharmaceutically acceptable
Prior art date
Application number
IE2558/82A
Other languages
English (en)
Other versions
IE822558L (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/366,248 external-priority patent/US4536578A/en
Priority claimed from US06/366,244 external-priority patent/US4390544A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IE822558L publication Critical patent/IE822558L/xx
Publication of IE54065B1 publication Critical patent/IE54065B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IE2558/82A 1982-04-09 1982-10-26 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl-)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments IE54065B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/366,248 US4536578A (en) 1982-04-09 1982-04-09 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US06/366,244 US4390544A (en) 1982-04-09 1982-04-09 {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p

Publications (2)

Publication Number Publication Date
IE822558L IE822558L (en) 1983-10-09
IE54065B1 true IE54065B1 (en) 1989-06-07

Family

ID=27003274

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2558/82A IE54065B1 (en) 1982-04-09 1982-10-26 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl-)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments

Country Status (16)

Country Link
EP (1) EP0091511B1 (enEXAMPLES)
KR (1) KR880002013B1 (enEXAMPLES)
AT (1) ATE34170T1 (enEXAMPLES)
CA (1) CA1209146A (enEXAMPLES)
DE (1) DE3278471D1 (enEXAMPLES)
DK (1) DK474382A (enEXAMPLES)
ES (1) ES8400431A1 (enEXAMPLES)
FI (1) FI823433A7 (enEXAMPLES)
GR (1) GR77706B (enEXAMPLES)
HU (1) HU191075B (enEXAMPLES)
IE (1) IE54065B1 (enEXAMPLES)
IL (1) IL66866A (enEXAMPLES)
NO (1) NO823556L (enEXAMPLES)
NZ (1) NZ202044A (enEXAMPLES)
PH (1) PH18252A (enEXAMPLES)
PT (1) PT75726A (enEXAMPLES)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5055476A (en) * 1990-08-13 1991-10-08 Hoechst-Roussel Pharmaceuticals Incorporated 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives
US5114936A (en) * 1990-08-23 1992-05-19 Hoechst-Roussel Pharmaceuticals Incorporated 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use
US5750542A (en) 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
SG49055A1 (en) * 1991-03-28 1998-05-18 Eisai Co Ltd Heterocyclic-cyclic amine derivatives
US5225412A (en) * 1991-04-29 1993-07-06 Hoechst-Roussel Pharmaceuticals Incorporated Benzoisothiazole-and benzisoxazole-3-carboxamides
US5143923B1 (en) * 1991-04-29 1993-11-02 Hoechst-Roussel Pharmaceuticals Incorporated Benzoisothiazole-and benzisoxazole-3-carboxamides
MX377708B (es) * 2012-12-19 2025-03-11 Henkel Ag & Co Kgaa Método para la amortiguación de sonido y/o aislamiento de sonido de componentes.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60390C (fi) * 1975-03-05 1982-01-11 Sumitomo Chemical Co Foerfarande foer framstaellning av neuroleptiska butyrofenoner
JPS6043064B2 (ja) * 1979-11-28 1985-09-26 ウェルファイド株式会社 新規イソオキサゾ−ル誘導体

Also Published As

Publication number Publication date
FI823433L (fi) 1983-10-10
IL66866A0 (en) 1982-12-31
ES516830A0 (es) 1983-10-16
NZ202044A (en) 1987-04-30
PT75726A (en) 1982-11-01
FI823433A7 (fi) 1983-10-10
EP0091511B1 (en) 1988-05-11
IL66866A (en) 1987-08-31
HU191075B (en) 1987-01-28
FI823433A0 (fi) 1982-10-08
IE822558L (en) 1983-10-09
KR880002013B1 (ko) 1988-10-12
DK474382A (da) 1983-10-10
PH18252A (en) 1985-05-13
GR77706B (enEXAMPLES) 1984-09-25
NO823556L (no) 1983-10-10
ATE34170T1 (de) 1988-05-15
DE3278471D1 (en) 1988-06-16
EP0091511A2 (en) 1983-10-19
EP0091511A3 (en) 1984-12-12
CA1209146A (en) 1986-08-05
ES8400431A1 (es) 1983-10-16
KR840001974A (ko) 1984-06-07

Similar Documents

Publication Publication Date Title
CA2067404C (en) Benzoisothiazole and benzoisoxazole-3-carboxamides a process for their preparation and their use as medicaments
JP4249012B2 (ja) 新規な２ｈ−ピリダジン−３−オン誘導体、該誘導体を含有する医薬組成物及びこの有効成分の製法
IE54065B1 (en) 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl-)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments
EP0091512B1 (en) 6-fluoro-3-(3-(1-heterocyclo)propyl)-1,2-benzisoxazoles, a process for their preparation, pharmaceutical compositions thereof and their use as medicaments
US4536578A (en) 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
EP0458234B1 (en) 3-[1,Thiazolidinylbutyl-4-piperazinyl]-1H-indazoles, a process for their preparation and their use as medicaments
US4604395A (en) 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4610988A (en) 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4390544A (en) {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4609658A (en) 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
JP2564719B2 (ja) ８−アザビシクロ〔３．２．１〕オクチルアルキルチアゾリジノン類
KR880002511B1 (ko) 1-[3-(6-플루오로-1,2-벤즈이속사졸-3-일)프로필]-4-(치환된)-피페리딘 및 이의 제조방법
US5102889A (en) 2-(4-piperidinyl)-1H-pyrido[4,3-b]indol-1-ones and related compounds
US4598152A (en) 6-fluoro-3-[3-(oxoheterocyclo)propyl]-1,2-benzisoxazoles
US4822796A (en) 1-((Phenothiazin-10-yl)alkyl)-alpha-phenyl-4-piperidinemethanols and pharmaceutical use
US4812456A (en) 1-(N-(2-alkylthio-10H-phenothiazin-10-yl)alkyl)-4-benzoylpiperidines and pharmaceutical use
US4591586A (en) 6-fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles for treatment of pain, hypertension and psychoses
US4524209A (en) 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles