IE53883B1 - Preservative and fixative preparations for biological systems - Google Patents
Preservative and fixative preparations for biological systemsInfo
- Publication number
- IE53883B1 IE53883B1 IE208/83A IE20883A IE53883B1 IE 53883 B1 IE53883 B1 IE 53883B1 IE 208/83 A IE208/83 A IE 208/83A IE 20883 A IE20883 A IE 20883A IE 53883 B1 IE53883 B1 IE 53883B1
- Authority
- IE
- Ireland
- Prior art keywords
- mixture
- composition according
- weight
- plastic
- base strip
- Prior art date
Links
- 239000000834 fixative Substances 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 230000002335 preservative effect Effects 0.000 title claims description 14
- 239000003755 preservative agent Substances 0.000 title claims description 13
- 239000000203 mixture Substances 0.000 claims abstract description 107
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims abstract description 24
- 230000002380 cytological effect Effects 0.000 claims abstract description 16
- 239000004202 carbamide Substances 0.000 claims abstract description 14
- 229920005862 polyol Polymers 0.000 claims abstract description 13
- 150000003077 polyols Chemical class 0.000 claims abstract description 13
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 claims abstract description 12
- 150000003751 zinc Chemical class 0.000 claims abstract description 12
- 230000001900 immune effect Effects 0.000 claims abstract description 11
- 150000007522 mineralic acids Chemical class 0.000 claims abstract description 5
- 229920003023 plastic Polymers 0.000 claims description 18
- 239000004033 plastic Substances 0.000 claims description 18
- 239000002202 Polyethylene glycol Substances 0.000 claims description 17
- 229920001223 polyethylene glycol Polymers 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000012360 testing method Methods 0.000 claims description 13
- 239000004615 ingredient Substances 0.000 claims description 11
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical group [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 10
- 239000004246 zinc acetate Substances 0.000 claims description 10
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 9
- LEQAOMBKQFMDFZ-UHFFFAOYSA-N glyoxal Chemical group O=CC=O LEQAOMBKQFMDFZ-UHFFFAOYSA-N 0.000 claims description 8
- ZNZYKNKBJPZETN-WELNAUFTSA-N Dialdehyde 11678 Chemical compound N1C2=CC=CC=C2C2=C1[C@H](C[C@H](/C(=C/O)C(=O)OC)[C@@H](C=C)C=O)NCC2 ZNZYKNKBJPZETN-WELNAUFTSA-N 0.000 claims description 7
- 239000004793 Polystyrene Substances 0.000 claims description 7
- 239000003153 chemical reaction reagent Substances 0.000 claims description 7
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 claims description 7
- 239000011521 glass Substances 0.000 claims description 6
- 229920000193 polymethacrylate Polymers 0.000 claims description 6
- 229920002223 polystyrene Polymers 0.000 claims description 6
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical group [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims description 6
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 5
- 239000002250 absorbent Substances 0.000 claims description 5
- 230000002745 absorbent Effects 0.000 claims description 5
- 230000008021 deposition Effects 0.000 claims description 5
- 229940015043 glyoxal Drugs 0.000 claims description 4
- 239000011592 zinc chloride Substances 0.000 claims description 3
- 235000005074 zinc chloride Nutrition 0.000 claims description 3
- 229920000058 polyacrylate Polymers 0.000 claims 4
- 150000007524 organic acids Chemical class 0.000 abstract description 4
- 230000001590 oxidative effect Effects 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 13
- 239000000427 antigen Substances 0.000 description 9
- 102000036639 antigens Human genes 0.000 description 9
- 108091007433 antigens Proteins 0.000 description 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- -1 about 5 to 10% Substances 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 229960004319 trichloroacetic acid Drugs 0.000 description 5
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 239000000084 colloidal system Substances 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 239000004816 latex Substances 0.000 description 3
- 229920000126 latex Polymers 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 239000004926 polymethyl methacrylate Substances 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 3
- 239000004375 Dextrin Substances 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- WZUVPPKBWHMQCE-UHFFFAOYSA-N Haematoxylin Chemical compound C12=CC(O)=C(O)C=C2CC2(O)C1C1=CC=C(O)C(O)=C1OC2 WZUVPPKBWHMQCE-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 238000002405 diagnostic procedure Methods 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 229920001515 polyalkylene glycol Polymers 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 208000006379 syphilis Diseases 0.000 description 2
- 239000008096 xylene Substances 0.000 description 2
- AXDJCCTWPBKUKL-UHFFFAOYSA-N 4-[(4-aminophenyl)-(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]aniline;hydron;chloride Chemical compound Cl.C1=CC(=N)C(C)=CC1=C(C=1C=CC(N)=CC=1)C1=CC=C(N)C=C1 AXDJCCTWPBKUKL-UHFFFAOYSA-N 0.000 description 1
- HZLHRDBTVSZCBS-GHTYLULLSA-N 4-[(z)-(4-aminophenyl)-(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline;hydrochloride Chemical compound Cl.C1=CC(=N)C(C)=C\C1=C(C=1C=C(C)C(N)=CC=1)\C1=CC=C(N)C=C1 HZLHRDBTVSZCBS-GHTYLULLSA-N 0.000 description 1
- RZZPDXZPRHQOCG-OJAKKHQRSA-O CDP-choline(1+) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-O 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 229920005372 Plexiglas® Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 125000002877 alkyl aryl group Chemical group 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000536 complexating effect Effects 0.000 description 1
- 239000008139 complexing agent Substances 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000010944 ethyl methyl cellulose Nutrition 0.000 description 1
- 238000005189 flocculation Methods 0.000 description 1
- 230000016615 flocculation Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000001456 gonadotroph Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000000677 immunologic agent Substances 0.000 description 1
- 229940124541 immunological agent Drugs 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- VHGXRGXCDVQIKS-KRWDZBQOSA-N methyl (2s)-3-(4-methylphenyl)sulfonyloxy-2-(phenylmethoxycarbonylamino)propanoate Chemical compound C([C@@H](C(=O)OC)NC(=O)OCC=1C=CC=CC=1)OS(=O)(=O)C1=CC=C(C)C=C1 VHGXRGXCDVQIKS-KRWDZBQOSA-N 0.000 description 1
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 1
- 229920003087 methylethyl cellulose Polymers 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920005553 polystyrene-acrylate Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 238000010944 pre-mature reactiony Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- QOYONWHPQJZMOX-UHFFFAOYSA-N pyrrolidin-2-one;urea Chemical compound NC(N)=O.O=C1CCCN1 QOYONWHPQJZMOX-UHFFFAOYSA-N 0.000 description 1
- 238000012128 rapid plasma reagin Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000007447 staining method Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
- LIAVVEHHDCBKEB-UHFFFAOYSA-L zinc urea diacetate Chemical compound NC(=O)N.C(C)(=O)[O-].[Zn+2].C(C)(=O)[O-] LIAVVEHHDCBKEB-UHFFFAOYSA-L 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N2001/305—Fixative compositions
- G01N2001/307—Fixative compositions non-toxic, no Hg, no formaldehyde
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/02—Food
- G01N33/04—Dairy products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Sampling And Sample Adjustment (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Lubricants (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/345,589 US4493821A (en) | 1982-02-04 | 1982-02-04 | Preservative and fixative preparations for biological systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE830208L IE830208L (en) | 1983-08-04 |
| IE53883B1 true IE53883B1 (en) | 1989-03-29 |
Family
ID=23355638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE208/83A IE53883B1 (en) | 1982-02-04 | 1983-02-03 | Preservative and fixative preparations for biological systems |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4493821A (OSRAM) |
| JP (1) | JPS58206965A (OSRAM) |
| AR (1) | AR231355A1 (OSRAM) |
| AU (1) | AU557598B2 (OSRAM) |
| BE (1) | BE895827A (OSRAM) |
| BR (1) | BR8300573A (OSRAM) |
| CA (1) | CA1203150A (OSRAM) |
| DE (1) | DE3303788A1 (OSRAM) |
| DK (1) | DK41283A (OSRAM) |
| FR (1) | FR2521302B1 (OSRAM) |
| GB (1) | GB2114291B (OSRAM) |
| IE (1) | IE53883B1 (OSRAM) |
| IN (1) | IN159875B (OSRAM) |
| IT (1) | IT1193663B (OSRAM) |
| NL (1) | NL8300433A (OSRAM) |
| SE (1) | SE8300551L (OSRAM) |
| ZA (1) | ZA83751B (OSRAM) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4637986A (en) * | 1983-08-22 | 1987-01-20 | Ortho Diagnostic Systems, Inc. | Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count |
| US5188935A (en) * | 1984-05-31 | 1993-02-23 | Coulter Electronics, Inc. | Reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes |
| AU4966785A (en) * | 1984-10-04 | 1986-04-17 | Preco, Inc. | Stabilization of biological substances |
| US4745071A (en) * | 1985-09-05 | 1988-05-17 | Sequoia-Turner Corporation | Method for the volumetric differentiation of blood cells types |
| US4816410A (en) * | 1986-10-29 | 1989-03-28 | Coulter Corporation | Control slide for immunoassay kit and method of making same |
| US5045474A (en) * | 1987-05-28 | 1991-09-03 | Sequoia-Turner Corporation (Unipath) | Semi-automatic process for white cell differential count |
| US4946669A (en) * | 1987-10-09 | 1990-08-07 | Siegfried Barry A | Histological fixatives |
| US5008202A (en) * | 1988-11-29 | 1991-04-16 | Sequoia Turner Corporation | Blood diluent for red blood cell analysis |
| GB8830197D0 (en) * | 1988-12-23 | 1989-02-22 | Univ Dundee | Tissue preservation medium |
| US5411894A (en) * | 1990-03-20 | 1995-05-02 | Abbott Laboratories | Method of using tissue and cell adhesive preparations for biological test systems |
| US5256571A (en) * | 1991-05-01 | 1993-10-26 | Cytyc Corporation | Cell preservative solution |
| US5849517A (en) * | 1991-05-08 | 1998-12-15 | Streck Laboratories, Inc. | Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same |
| US5460797A (en) * | 1991-05-08 | 1995-10-24 | Streck Laboratories, Inc. | Method for fixing tissues and cells for analysis using oxazolidine compounds |
| US5459073A (en) * | 1991-05-08 | 1995-10-17 | Streck Laboratories, Inc. | Method and composition for preserving antigens and process for utilizing cytological material produced by same |
| JP2631796B2 (ja) * | 1991-06-20 | 1997-07-16 | 呉羽化学工業株式会社 | 診断用試験スライド及びその製造方法 |
| US5998483A (en) * | 1991-09-20 | 1999-12-07 | Camiener; Gerald W. | Glyoxal-containing preservative compositions |
| AU669673B2 (en) * | 1991-09-20 | 1996-06-20 | Gerald W. Camiener | Methods and compositions with aldehyde stabilizing solution |
| WO1994007532A1 (en) * | 1992-09-10 | 1994-04-14 | Streck Laboratories, Inc. | Method and composition for preserving antigens and process for utilizing cytological material produced by same |
| US5401625A (en) * | 1993-06-24 | 1995-03-28 | E. K. Industries, Inc. | Histological composition for light microscopy |
| AU3615297A (en) * | 1997-07-15 | 1999-02-10 | Bernard Pajak | Method for fixing and embedding tissues for histological preparations |
| EP1092141B1 (en) * | 1998-06-30 | 2004-06-02 | Lamina, Inc. | Cytological and histological fixative composition and methods of use |
| BR0112385A (pt) * | 2000-06-21 | 2003-06-17 | Digene Corp | Meio de coleta universal |
| ATE285070T1 (de) * | 2003-03-05 | 2005-01-15 | Milestone Srl | Fixierungslösung |
| US7368132B2 (en) * | 2004-10-27 | 2008-05-06 | Medical Chemical Corporation | Glyoxal/zinc fixative |
| US20090226059A1 (en) * | 2008-02-12 | 2009-09-10 | Richard Levenson | Tissue Processing And Assessment |
| US20130045503A1 (en) * | 2010-03-12 | 2013-02-21 | Riken | Clearing reagent for biological material, and use thereof |
| US8338130B2 (en) | 2011-02-25 | 2012-12-25 | Medical Chemical Corporation | Universal fecal fixative comprising a low molecular weight alcohol, a zinc salt and an organic acid |
| CN107300496B (zh) | 2011-05-20 | 2020-11-24 | 国立研究开发法人理化学研究所 | 生物材料用透明化试剂、及其利用 |
| WO2012176065A2 (en) * | 2011-06-24 | 2012-12-27 | Biotechnology Developers, S.A. | Method compositions and device for preparing cytological specimens |
| US10267714B2 (en) | 2013-08-14 | 2019-04-23 | Riken | Composition for preparing biomaterial with excellent light-transmitting property, and use thereof |
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| WO2025072741A1 (en) * | 2023-09-29 | 2025-04-03 | Board Of Regents, The University Of Texas System | Preservatives for molecular sample analysis with sample collection devices |
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| US3415361A (en) * | 1966-12-22 | 1968-12-10 | Miles Lab | Test device and container therefor |
| US2092566A (en) * | 1935-09-13 | 1937-09-07 | Wright Arthur | Tester |
| BE496199A (OSRAM) * | 1950-01-07 | 1900-01-01 | ||
| BE513161A (OSRAM) * | 1951-07-28 | |||
| US3088875A (en) * | 1959-10-27 | 1963-05-07 | Hyland Lab | Immunological diagnostics utilizing polystyrene latex particles of 0.15 to 0.25 micron |
| US3562384A (en) * | 1960-11-08 | 1971-02-09 | Miles Lab | Immunological indicator and test system |
| US3236732A (en) * | 1962-01-22 | 1966-02-22 | Edward R Arquilla | Pregnancy test method and immunological indicator therefor |
| BE613680A (OSRAM) * | 1961-03-07 | |||
| US3074853A (en) * | 1961-06-22 | 1963-01-22 | Hynson Westcott & Dunning Inc | Serological test card with color solid as visualizing agent |
| US3171783A (en) * | 1962-08-15 | 1965-03-02 | Hyland Lab | Diagnostic procedure |
| NL132816C (OSRAM) * | 1963-08-23 | |||
| NL125235C (OSRAM) * | 1965-04-15 | |||
| US3502437A (en) * | 1967-03-13 | 1970-03-24 | Haematronics Inc | Identification card |
| US3579306A (en) * | 1969-01-22 | 1971-05-18 | Organon | Diagnostic test device |
| US3624197A (en) * | 1969-09-04 | 1971-11-30 | Philip Schain | Water-soluble tissue infiltrating and embedding compositions |
| US3790663A (en) * | 1970-07-07 | 1974-02-05 | Us Health | Preparation of dry antiserum coated solid-phase for radioimmunoassay of antigens |
| US3737335A (en) * | 1970-07-17 | 1973-06-05 | S Feinberg | Method for preparing a specimen |
| US3666421A (en) * | 1971-04-05 | 1972-05-30 | Organon | Diagnostic test slide |
| US3862300A (en) * | 1973-03-07 | 1975-01-21 | Applied Bioscience | Histological fixative |
| US3966897A (en) * | 1973-04-02 | 1976-06-29 | Marine Colloids, Inc. | Medium for use in bioassay and method of using same |
| US3975162A (en) * | 1974-03-13 | 1976-08-17 | Marine Colloids, Inc. | Applying reagent to medium and device therefor |
| DE2826363C2 (de) * | 1978-06-16 | 1984-08-16 | Merck Patent Gmbh, 6100 Darmstadt | Deckfolie zur Verwendung in mikroskopischen Färbeverfahren und Verfahren zu ihrer Herstellung |
| US4234316A (en) * | 1979-04-02 | 1980-11-18 | Fmc Corporation | Device for delivering measured quantities of reagents into assay medium |
| US4387164A (en) * | 1980-11-05 | 1983-06-07 | Fmc Corporation | Method and apparatus for chemical analysis using reactive reagents dispersed in soluble film |
-
1982
- 1982-02-04 US US06/345,589 patent/US4493821A/en not_active Expired - Lifetime
-
1983
- 1983-01-31 CA CA000420577A patent/CA1203150A/en not_active Expired
- 1983-01-31 GB GB08302580A patent/GB2114291B/en not_active Expired
- 1983-02-02 DK DK41283A patent/DK41283A/da not_active Application Discontinuation
- 1983-02-02 SE SE8300551A patent/SE8300551L/ not_active Application Discontinuation
- 1983-02-03 AU AU10994/83A patent/AU557598B2/en not_active Ceased
- 1983-02-03 IE IE208/83A patent/IE53883B1/en unknown
- 1983-02-03 AR AR292029A patent/AR231355A1/es active
- 1983-02-04 DE DE19833303788 patent/DE3303788A1/de not_active Withdrawn
- 1983-02-04 BE BE0/210063A patent/BE895827A/fr not_active IP Right Cessation
- 1983-02-04 FR FR8301773A patent/FR2521302B1/fr not_active Expired
- 1983-02-04 NL NL8300433A patent/NL8300433A/nl not_active Application Discontinuation
- 1983-02-04 IT IT19451/83A patent/IT1193663B/it active
- 1983-02-04 ZA ZA83751A patent/ZA83751B/xx unknown
- 1983-02-04 BR BR8300573A patent/BR8300573A/pt unknown
- 1983-02-04 JP JP58017296A patent/JPS58206965A/ja active Pending
- 1983-02-11 IN IN166/CAL/83A patent/IN159875B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA83751B (en) | 1983-11-30 |
| CA1203150A (en) | 1986-04-15 |
| SE8300551L (sv) | 1983-08-05 |
| AR231355A1 (es) | 1984-10-31 |
| SE8300551D0 (sv) | 1983-02-02 |
| AU557598B2 (en) | 1986-12-24 |
| JPS58206965A (ja) | 1983-12-02 |
| BE895827A (fr) | 1983-05-30 |
| NL8300433A (nl) | 1983-09-01 |
| US4493821A (en) | 1985-01-15 |
| DE3303788A1 (de) | 1983-08-11 |
| IE830208L (en) | 1983-08-04 |
| GB2114291A (en) | 1983-08-17 |
| GB2114291B (en) | 1985-07-31 |
| IT8319451A0 (it) | 1983-02-04 |
| FR2521302A1 (fr) | 1983-08-12 |
| IN159875B (OSRAM) | 1987-06-13 |
| FR2521302B1 (fr) | 1986-12-26 |
| DK41283A (da) | 1983-08-05 |
| BR8300573A (pt) | 1983-11-08 |
| DK41283D0 (da) | 1983-02-02 |
| GB8302580D0 (en) | 1983-03-02 |
| IT1193663B (it) | 1988-07-21 |
| AU1099483A (en) | 1983-08-11 |
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