IE46036B1 - Prostacyclin and derivatives thereof - Google Patents

Prostacyclin and derivatives thereof

Info

Publication number
IE46036B1
IE46036B1 IE950/77A IE95077A IE46036B1 IE 46036 B1 IE46036 B1 IE 46036B1 IE 950/77 A IE950/77 A IE 950/77A IE 95077 A IE95077 A IE 95077A IE 46036 B1 IE46036 B1 IE 46036B1
Authority
IE
Ireland
Prior art keywords
compound
deoxy
didehydro
epoxyprostaglandin
prostaglandin
Prior art date
Application number
IE950/77A
Other languages
English (en)
Other versions
IE46036L (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE46036L publication Critical patent/IE46036L/xx
Publication of IE46036B1 publication Critical patent/IE46036B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Furan Compounds (AREA)
IE950/77A 1976-05-11 1977-05-10 Prostacyclin and derivatives thereof IE46036B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB19384/76A GB1583961A (en) 1976-05-11 1976-05-11 Prostacyclin and derivatives thereof
GB3415176 1976-08-17
GB3654776 1976-09-03
GB4344576 1976-10-20
GB5306076 1976-12-20
GB1338977 1977-03-30

Publications (2)

Publication Number Publication Date
IE46036L IE46036L (en) 1977-11-11
IE46036B1 true IE46036B1 (en) 1983-02-09

Family

ID=27546654

Family Applications (1)

Application Number Title Priority Date Filing Date
IE950/77A IE46036B1 (en) 1976-05-11 1977-05-10 Prostacyclin and derivatives thereof

Country Status (12)

Country Link
JP (1) JPS52136161A (de)
BE (1) BE854463A (de)
CH (1) CH637948A5 (de)
DE (1) DE2720999C2 (de)
DK (1) DK149953C (de)
FR (1) FR2351111A1 (de)
GB (1) GB1583961A (de)
IE (1) IE46036B1 (de)
IL (1) IL52053A (de)
NL (1) NL181973C (de)
NZ (1) NZ184057A (de)
SE (1) SE436647B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
IT1088036B (it) 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
ZA787353B (en) * 1978-05-17 1980-08-27 Wellcome Found Pharmaceutical formulations
US4430340A (en) * 1978-07-17 1984-02-07 The Upjohn Company Stabilization of PGI2 compounds with surfactants
IL58384A0 (en) 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
ZA815504B (en) * 1980-09-15 1982-08-25 Upjohn Co Crystalline pgi2 methyl ester
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
DE3438870A1 (de) * 1983-12-13 1985-06-13 Stellmacher, Gerhard, Ing.(grad.), 8501 Schwaig Spannvorrichtung fuer holzbearbeitungsmaschinen
JP5697260B2 (ja) 2009-11-13 2015-04-08 東レ株式会社 糖尿病の治療または予防薬
HU231031B1 (hu) 2016-03-23 2019-12-30 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Megnövelt stabilitású epoprostenol nátrium és eljárás előállítására

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs

Also Published As

Publication number Publication date
IE46036L (en) 1977-11-11
IL52053A0 (en) 1977-07-31
NL181973C (nl) 1987-12-16
DK149953C (da) 1987-06-29
JPS619953B2 (de) 1986-03-27
CH637948A5 (en) 1983-08-31
IL52053A (en) 1983-09-30
DK149953B (da) 1986-11-03
NZ184057A (en) 1979-10-25
DE2720999A1 (de) 1977-11-24
SE7705423L (sv) 1977-11-12
NL181973B (nl) 1987-07-16
NL7705141A (nl) 1977-11-15
DE2720999C2 (de) 1986-09-18
FR2351111A1 (fr) 1977-12-09
GB1583961A (en) 1981-02-04
DK205377A (da) 1977-11-12
JPS52136161A (en) 1977-11-14
BE854463A (fr) 1977-11-10
SE436647B (sv) 1985-01-14

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Legal Events

Date Code Title Description
MK9A Patent expired