IE45730L - Methylamine derivatives - Google Patents

Methylamine derivatives

Info

Publication number
IE45730L
IE45730L IE771131A IE113177A IE45730L IE 45730 L IE45730 L IE 45730L IE 771131 A IE771131 A IE 771131A IE 113177 A IE113177 A IE 113177A IE 45730 L IE45730 L IE 45730L
Authority
IE
Ireland
Prior art keywords
methylamine derivatives
toxic addition
methylamine
derivatives
gb1565021a
Prior art date
Application number
IE771131A
Other versions
IE45730B1 (en
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Priority to IE1277/82A priority Critical patent/IE45731B1/en
Priority to IE1278/82A priority patent/IE45732B1/en
Publication of IE45730L publication Critical patent/IE45730L/en
Publication of IE45730B1 publication Critical patent/IE45730B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The methylamine derivatives of general formula: <IMAGE> and their non-toxic addition salts, in which R represents n-propyl, isopropyl, isobutyl or allyl, are obtained by reducing the corresponding isocyanate by means of lithium aluminium hydride in an inert and anhydrous medium and then reacting the base obtained with an acid to produce a non-toxic addition salt. [GB1565021A]
IE1131/77A 1976-06-03 1977-06-01 Pharmaceutical compositions containing alkylamine derivatives IE45730B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IE1277/82A IE45731B1 (en) 1976-06-03 1977-06-01 Methylamine derivatives and process for preparing the same
IE1278/82A IE45732B1 (en) 1976-06-03 1977-06-01 Methylamine derivatives and process for preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE167579A BE842528R (en) 1976-06-03 1976-06-03 METHYLAMINE ACTIVE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND THE PROCESSES FOR THE PREPARATION OF THESE DERIVATIVES AND COMPOSITIONS

Publications (2)

Publication Number Publication Date
IE45730L true IE45730L (en) 1977-12-03
IE45730B1 IE45730B1 (en) 1982-11-17

Family

ID=3842891

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1131/77A IE45730B1 (en) 1976-06-03 1977-06-01 Pharmaceutical compositions containing alkylamine derivatives

Country Status (9)

Country Link
BE (1) BE842528R (en)
CA (1) CA1076482A (en)
CH (4) CH624922A5 (en)
DE (1) DE2725245C2 (en)
GB (3) GB1565023A (en)
HU (1) HU175776B (en)
IE (1) IE45730B1 (en)
IT (1) IT1114869B (en)
OA (1) OA05675A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR61148B (en) * 1976-06-03 1978-09-27 Labaz Preparation process of active methylamine derivatives
DE3362734D1 (en) * 1982-01-18 1986-05-07 Exxon Research Engineering Co Secondary and tertiary amino alcohols
DE19827166A1 (en) 1998-06-18 1999-12-23 Merck Patent Gmbh Process for the catalytic disubstitution of carboxamides with at least one Grignard reagent
DE19827161A1 (en) 1998-06-18 1999-12-23 Merck Patent Gmbh Process for the catalytic, symmetrical disubstitution of carboxamides with Grignard reagents
JP2003524588A (en) * 1998-06-18 2003-08-19 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング Geminal substituted amine

Also Published As

Publication number Publication date
GB1565021A (en) 1980-04-16
CH623559A5 (en) 1981-06-15
HU175776B (en) 1980-10-28
IE45730B1 (en) 1982-11-17
DE2725245A1 (en) 1977-12-15
CH623560A5 (en) 1981-06-15
CA1076482A (en) 1980-04-29
CH624389A5 (en) 1981-07-31
BE842528R (en) 1976-12-03
GB1565023A (en) 1980-04-16
IT1114869B (en) 1986-01-27
DE2725245C2 (en) 1986-09-04
GB1565022A (en) 1980-04-16
CH624922A5 (en) 1981-08-31
OA05675A (en) 1981-05-31

Similar Documents

Publication Publication Date Title
EP0397608A3 (en) High energy and high power lithium batteries, and method for producing the same
IE802702L (en) Improvements to a non-aqueous li/mno2 cell
IE45631L (en) 4-hydroxyphenylalkanolamine derivatives.
AU502909B2 (en) Reversible cathode for use with lithium alloy anodes
IE45730L (en) Methylamine derivatives
IE45109L (en) N-2-imidazolidinylidene-benzeneamine
ES469265A1 (en) {107 -Aminocarboxylic acid amide phosphates
IE45009L (en) Phenoxyphenoxy propionic acid esters
IE780198L (en) Oxadiazolopyrimidine derivatives
IE45222L (en) 2-loweralkyl-2- or -3-cephem-4-carboxylic acids.
IE38139L (en) 1-ethyl-imidazoles
GB1243593A (en) Improvements in or relating to alkyl prolines and the manufacture thereof
ES478643A1 (en) Therapeutically useful N-phenylaniline derivatives
IE42390L (en) Substituted indoles.
GB1448003A (en) 1,2,4-triazolin-5-ones and their use as herbicidal compounds
IE45606L (en) Prostanoic acid derivatives
IE42933L (en) Glyoxylic acid derivatives.
IE44862L (en) Cinnamides
IE42962L (en) Phthalimidine and benzisothiazoline derivatives.
GB1509457A (en) Pyridine derivatives
IE45436L (en) 12-azaprostanoic acid derivatives
ES445336A1 (en) Oxoindanylpropionic acids and process for the preparation thereof
GB1541185A (en) 5-fluorouracil derivatives and their preparation
AU559040B2 (en) Penicilline derivative
IE44951L (en) Pyridoindoles