IT1114869B - ACTIVE METHYLAMINE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND PROCEDURES TO PREPARE THE SAID DERIVATIVES AND THOSE COMPOSITIONS - Google Patents

ACTIVE METHYLAMINE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND PROCEDURES TO PREPARE THE SAID DERIVATIVES AND THOSE COMPOSITIONS

Info

Publication number
IT1114869B
IT1114869B IT24186/77A IT2418677A IT1114869B IT 1114869 B IT1114869 B IT 1114869B IT 24186/77 A IT24186/77 A IT 24186/77A IT 2418677 A IT2418677 A IT 2418677A IT 1114869 B IT1114869 B IT 1114869B
Authority
IT
Italy
Prior art keywords
derivatives
procedures
prepare
active
methylamine
Prior art date
Application number
IT24186/77A
Other languages
Italian (it)
Inventor
Charles Pigerol
Pierre Eymard
Jean-Claude Vernieres
Madelfine Broll
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Application granted granted Critical
Publication of IT1114869B publication Critical patent/IT1114869B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT24186/77A 1976-06-03 1977-05-31 ACTIVE METHYLAMINE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND PROCEDURES TO PREPARE THE SAID DERIVATIVES AND THOSE COMPOSITIONS IT1114869B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE167579A BE842528R (en) 1976-06-03 1976-06-03 METHYLAMINE ACTIVE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND THE PROCESSES FOR THE PREPARATION OF THESE DERIVATIVES AND COMPOSITIONS

Publications (1)

Publication Number Publication Date
IT1114869B true IT1114869B (en) 1986-01-27

Family

ID=3842891

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24186/77A IT1114869B (en) 1976-06-03 1977-05-31 ACTIVE METHYLAMINE DERIVATIVES, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND PROCEDURES TO PREPARE THE SAID DERIVATIVES AND THOSE COMPOSITIONS

Country Status (9)

Country Link
BE (1) BE842528R (en)
CA (1) CA1076482A (en)
CH (4) CH624922A5 (en)
DE (1) DE2725245C2 (en)
GB (3) GB1565023A (en)
HU (1) HU175776B (en)
IE (1) IE45730B1 (en)
IT (1) IT1114869B (en)
OA (1) OA05675A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR61148B (en) * 1976-06-03 1978-09-27 Labaz Preparation process of active methylamine derivatives
DE3362734D1 (en) * 1982-01-18 1986-05-07 Exxon Research Engineering Co Secondary and tertiary amino alcohols
DE19827166A1 (en) 1998-06-18 1999-12-23 Merck Patent Gmbh Process for the catalytic disubstitution of carboxamides with at least one Grignard reagent
DE19827161A1 (en) 1998-06-18 1999-12-23 Merck Patent Gmbh Process for the catalytic, symmetrical disubstitution of carboxamides with Grignard reagents
JP2003524588A (en) * 1998-06-18 2003-08-19 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング Geminal substituted amine

Also Published As

Publication number Publication date
GB1565021A (en) 1980-04-16
CH623559A5 (en) 1981-06-15
HU175776B (en) 1980-10-28
IE45730B1 (en) 1982-11-17
DE2725245A1 (en) 1977-12-15
CH623560A5 (en) 1981-06-15
CA1076482A (en) 1980-04-29
CH624389A5 (en) 1981-07-31
BE842528R (en) 1976-12-03
GB1565023A (en) 1980-04-16
DE2725245C2 (en) 1986-09-04
GB1565022A (en) 1980-04-16
CH624922A5 (en) 1981-08-31
OA05675A (en) 1981-05-31
IE45730L (en) 1977-12-03

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