IE44093B1 - New salts of the dimethylaminoethyl ester of p-chlorophenoxy acetic acid - Google Patents
New salts of the dimethylaminoethyl ester of p-chlorophenoxy acetic acidInfo
- Publication number
- IE44093B1 IE44093B1 IE75376A IE75376A IE44093B1 IE 44093 B1 IE44093 B1 IE 44093B1 IE 75376 A IE75376 A IE 75376A IE 75376 A IE75376 A IE 75376A IE 44093 B1 IE44093 B1 IE 44093B1
- Authority
- IE
- Ireland
- Prior art keywords
- ethyl
- dimethylamino
- chlorophenoxyacetate
- benzoic acid
- hydroxybenzoyl
- Prior art date
Links
- -1 dimethylaminoethyl ester Chemical class 0.000 title claims description 28
- 150000003839 salts Chemical class 0.000 title abstract description 30
- SODPIMGUZLOIPE-UHFFFAOYSA-N (4-chlorophenoxy)acetic acid Chemical compound OC(=O)COC1=CC=C(Cl)C=C1 SODPIMGUZLOIPE-UHFFFAOYSA-N 0.000 title 1
- XZTYGFHCIAKPGJ-UHFFFAOYSA-N Meclofenoxate Chemical class CN(C)CCOC(=O)COC1=CC=C(Cl)C=C1 XZTYGFHCIAKPGJ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 3
- 150000001875 compounds Chemical class 0.000 claims description 18
- 238000004519 manufacturing process Methods 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 13
- 230000008569 process Effects 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 10
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 9
- 239000005711 Benzoic acid Substances 0.000 claims description 8
- 239000000825 pharmaceutical preparation Substances 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 235000010233 benzoic acid Nutrition 0.000 claims description 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 231100000252 nontoxic Toxicity 0.000 claims description 3
- 230000003000 nontoxic effect Effects 0.000 claims description 3
- 229910052783 alkali metal Inorganic materials 0.000 claims description 2
- 239000012442 inert solvent Substances 0.000 claims description 2
- 229910017053 inorganic salt Inorganic materials 0.000 claims description 2
- 150000002576 ketones Chemical class 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 2
- FBZWYFBNIGSUPS-UHFFFAOYSA-N (2-chlorophenyl) ethaneperoxoate Chemical compound CC(=O)OOC1=CC=CC=C1Cl FBZWYFBNIGSUPS-UHFFFAOYSA-N 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 235000019640 taste Nutrition 0.000 abstract description 13
- YGTUPRIZNBMOFV-UHFFFAOYSA-N 2-(4-hydroxybenzoyl)benzoic acid Chemical compound OC(=O)C1=CC=CC=C1C(=O)C1=CC=C(O)C=C1 YGTUPRIZNBMOFV-UHFFFAOYSA-N 0.000 abstract description 6
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 150000002148 esters Chemical class 0.000 abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 30
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- LBORPQYMABOVPW-UHFFFAOYSA-N 2-benzoyl-3-hydroxybenzoic acid Chemical class OC(=O)C1=CC=CC(O)=C1C(=O)C1=CC=CC=C1 LBORPQYMABOVPW-UHFFFAOYSA-N 0.000 description 4
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- NCXUNZWLEYGQAH-UHFFFAOYSA-N 1-(dimethylamino)propan-2-ol Chemical compound CC(O)CN(C)C NCXUNZWLEYGQAH-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
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- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752516046 DE2516046C2 (de) | 1975-04-12 | 1975-04-12 | Salze des p-chlorphenoxyessigsaeure- dimethylaminoaethylesters mit 2-(p- hydroxybenzoyl)-benzoesaeuren, verfahren zu deren herstellung und diese enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE44093L IE44093L (en) | 1976-10-12 |
| IE44093B1 true IE44093B1 (en) | 1981-08-12 |
Family
ID=5943708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE75376A IE44093B1 (en) | 1975-04-12 | 1976-04-09 | New salts of the dimethylaminoethyl ester of p-chlorophenoxy acetic acid |
Country Status (13)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007044184A1 (en) * | 2005-10-07 | 2007-04-19 | Albemarle Corporation | Water soluble photoinitiator |
-
1975
- 1975-04-12 DE DE19752516046 patent/DE2516046C2/de not_active Expired
-
1976
- 1976-04-08 CH CH441576A patent/CH617665A5/de not_active IP Right Cessation
- 1976-04-08 GB GB1429276A patent/GB1484986A/en not_active Expired
- 1976-04-09 IE IE75376A patent/IE44093B1/en unknown
- 1976-04-09 NL NL7603757A patent/NL7603757A/xx not_active Application Discontinuation
- 1976-04-09 DK DK167376A patent/DK140631B/da not_active IP Right Cessation
- 1976-04-09 JP JP3948376A patent/JPS51148009A/ja active Pending
- 1976-04-09 ES ES446837A patent/ES446837A1/es not_active Expired
- 1976-04-09 AT AT264376A patent/AT342580B/de not_active IP Right Cessation
- 1976-04-09 LU LU74729A patent/LU74729A1/xx unknown
- 1976-04-09 FR FR7610432A patent/FR2306688A1/fr active Granted
- 1976-04-12 BE BE6045436A patent/BE840672A/xx unknown
-
1981
- 1981-12-30 MY MY8100289A patent/MY8100289A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7603757A (nl) | 1976-10-14 |
| IE44093L (en) | 1976-10-12 |
| BE840672A (fr) | 1976-10-12 |
| DK140631C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1980-04-14 |
| DE2516046C2 (de) | 1977-03-10 |
| ATA264376A (de) | 1977-08-15 |
| FR2306688B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-08-25 |
| LU74729A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-06-03 |
| JPS51148009A (en) | 1976-12-18 |
| FR2306688A1 (fr) | 1976-11-05 |
| DE2516046B1 (de) | 1976-07-01 |
| ES446837A1 (es) | 1977-06-01 |
| MY8100289A (en) | 1981-12-31 |
| DK167376A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-10-13 |
| AT342580B (de) | 1978-04-10 |
| CH617665A5 (en) | 1980-06-13 |
| GB1484986A (en) | 1977-09-08 |
| DK140631B (da) | 1979-10-15 |
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