IE43920B1 - Benzazepine derivatives and pharmceutical compositions containing them - Google Patents

Benzazepine derivatives and pharmceutical compositions containing them

Info

Publication number
IE43920B1
IE43920B1 IE1427/76A IE142776A IE43920B1 IE 43920 B1 IE43920 B1 IE 43920B1 IE 1427/76 A IE1427/76 A IE 1427/76A IE 142776 A IE142776 A IE 142776A IE 43920 B1 IE43920 B1 IE 43920B1
Authority
IE
Ireland
Prior art keywords
hydrogen
benzazepine
compound according
formula
renal
Prior art date
Application number
IE1427/76A
Other languages
English (en)
Other versions
IE43920L (en
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/592,708 external-priority patent/US4011319A/en
Priority claimed from US05/602,042 external-priority patent/US4052506A/en
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of IE43920L publication Critical patent/IE43920L/xx
Publication of IE43920B1 publication Critical patent/IE43920B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IE1427/76A 1975-07-02 1976-06-30 Benzazepine derivatives and pharmceutical compositions containing them IE43920B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/592,708 US4011319A (en) 1975-07-02 1975-07-02 Pharmaceutical compositions and methods involving benzazepine derivatives
US05/602,042 US4052506A (en) 1975-08-05 1975-08-05 Pharmaceutical compositions and method of producing anti-parkinsonism activity

Publications (2)

Publication Number Publication Date
IE43920L IE43920L (en) 1977-01-02
IE43920B1 true IE43920B1 (en) 1981-07-01

Family

ID=27081519

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1427/76A IE43920B1 (en) 1975-07-02 1976-06-30 Benzazepine derivatives and pharmceutical compositions containing them

Country Status (10)

Country Link
JP (1) JPS527981A (fr)
AU (1) AU507272B2 (fr)
CA (1) CA1079639A (fr)
DE (1) DE2629887A1 (fr)
FR (1) FR2315934A1 (fr)
GB (1) GB1561305A (fr)
IE (1) IE43920B1 (fr)
IL (1) IL49931A (fr)
LU (1) LU75269A1 (fr)
NL (1) NL7607184A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA777444B (en) * 1977-01-19 1978-10-25 Smithkline Corp Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines having dopaminergic activity
US4104379A (en) * 1977-01-19 1978-08-01 Smithkline Corporation Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4490392A (en) * 1977-08-11 1984-12-25 Tanabe Seiyaku Co., Ltd. Benzylalcohol derivative and process for preparing
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
EP0022330B1 (fr) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Compositions synergiques anti-hypertensives
EP0103830A3 (fr) * 1982-09-22 1985-07-31 Bayer Ag Dérivés de phényléthylamine comme stimulateurs de croissance
US5068326A (en) * 1989-04-03 1991-11-26 Kung Hank F Dopamine receptor ligands and imaging agents
GB9903671D0 (en) * 1999-02-17 1999-04-14 Cenes Ltd Dopamine D-1 receptor agonist compounds
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
JP2006526021A (ja) * 2003-05-22 2006-11-16 シェーリング　コーポレイション 肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
GB1118688A (en) * 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines

Also Published As

Publication number Publication date
FR2315934B1 (fr) 1978-11-17
NL7607184A (nl) 1977-01-04
CA1079639A (fr) 1980-06-17
AU507272B2 (en) 1980-02-07
LU75269A1 (fr) 1977-02-18
GB1561305A (en) 1980-02-20
FR2315934A1 (fr) 1977-01-28
AU1554076A (en) 1978-01-05
IL49931A0 (en) 1976-08-31
IE43920L (en) 1977-01-02
IL49931A (en) 1981-12-31
DE2629887A1 (de) 1977-01-20
JPS527981A (en) 1977-01-21

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