IE43213L - N-(6-acyloxybenzothiazol-2-yl)-n-phenyl ureas - Google Patents

N-(6-acyloxybenzothiazol-2-yl)-n-phenyl ureas

Info

Publication number
IE43213L
IE43213L IE760483A IE48376A IE43213L IE 43213 L IE43213 L IE 43213L IE 760483 A IE760483 A IE 760483A IE 48376 A IE48376 A IE 48376A IE 43213 L IE43213 L IE 43213L
Authority
IE
Ireland
Prior art keywords
acid
formula
carbon atoms
immune response
phenylurea
Prior art date
Application number
IE760483A
Other versions
IE43213B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/635,832 external-priority patent/US4046770A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE43213L publication Critical patent/IE43213L/en
Publication of IE43213B1 publication Critical patent/IE43213B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Novel phenylurea derivatives of the formula I are prepared by reacting an N-(6-hydroxybenzothiazol-2-yl)-N'-phenylurea of the formula II with an anhydride of acetic acid, propionic acid, isopropionic acid, butyric acid, isobutyric acid or benzoic acid in the presence of pyridine. In the formulae I and II, R is a hydrogen atom, a halogen atom, an alkyl group having 1-3 carbon atoms or an alkoxy group, and R' represents an alkyl radical having 1-3 carbon atoms or the phenyl radical. The novel phenylurea derivatives of the formula I are suitable for modifying the immune response, and they have a specific action against those cells which are active in the immune response. <IMAGE> [GB1535223A]
IE483/76A 1975-11-28 1976-03-09 N-(6-acyloxybenzothiazol-2-yl)-n'-phenyl (or substituted phenyl) ureas IE43213B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/635,832 US4046770A (en) 1974-08-30 1975-11-28 N-(6-acyloxybenzothiazol-2-yl)-N'-phenyl (or substituted phenyl)ureas

Publications (2)

Publication Number Publication Date
IE43213L true IE43213L (en) 1977-05-28
IE43213B1 IE43213B1 (en) 1981-01-14

Family

ID=24549286

Family Applications (1)

Application Number Title Priority Date Filing Date
IE483/76A IE43213B1 (en) 1975-11-28 1976-03-09 N-(6-acyloxybenzothiazol-2-yl)-n'-phenyl (or substituted phenyl) ureas

Country Status (24)

Country Link
JP (1) JPS5268176A (en)
AR (1) AR208767A1 (en)
AT (1) AT348539B (en)
AU (1) AU501516B2 (en)
BE (1) BE840048A (en)
CA (1) CA1067499A (en)
CH (1) CH608795A5 (en)
DD (1) DD126038A5 (en)
DE (1) DE2612541A1 (en)
DK (1) DK105676A (en)
ES (1) ES451021A1 (en)
FR (1) FR2332752A1 (en)
GB (1) GB1535223A (en)
GR (1) GR61856B (en)
HU (1) HU173987B (en)
IE (1) IE43213B1 (en)
IL (1) IL49187A (en)
MX (1) MX3136E (en)
NL (1) NL7602660A (en)
PL (1) PL100058B1 (en)
PT (1) PT64930B (en)
SE (1) SE417712B (en)
SU (1) SU648096A3 (en)
ZA (1) ZA761477B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4380640A (en) * 1980-01-21 1983-04-19 Ciba-Geigy Corporation Novel benzthiazolylurea derivatives, compositions containing them and their use as herbicides
ES2489297B1 (en) * 2013-01-22 2015-06-10 Consejo Superior De Investigaciones Científicas (Csic) BENZOTIAZOLES REPLACED AND ITS THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF HUMAN DISEASES

Also Published As

Publication number Publication date
NL7602660A (en) 1977-06-01
DE2612541A1 (en) 1977-06-02
BE840048A (en) 1976-09-27
DK105676A (en) 1977-05-29
SE7603521L (en) 1977-05-29
MX3136E (en) 1980-05-06
IE43213B1 (en) 1981-01-14
PT64930A (en) 1976-04-01
PL100058B1 (en) 1978-08-31
JPS5268176A (en) 1977-06-06
ES451021A1 (en) 1977-12-16
GB1535223A (en) 1978-12-13
FR2332752B1 (en) 1978-10-20
ZA761477B (en) 1977-10-26
FR2332752A1 (en) 1977-06-24
DD126038A5 (en) 1977-06-15
SU648096A3 (en) 1979-02-15
IL49187A0 (en) 1976-05-31
GR61856B (en) 1979-01-30
IL49187A (en) 1979-01-31
HU173987B (en) 1979-10-28
AU501516B2 (en) 1979-06-21
CH608795A5 (en) 1979-01-31
PT64930B (en) 1977-08-24
AR208767A1 (en) 1977-02-28
SE417712B (en) 1981-04-06
CA1067499A (en) 1979-12-04
AT348539B (en) 1979-02-26
AU1183676A (en) 1977-09-15
ATA217876A (en) 1978-07-15

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