IE41823L - Methylcobalamine - Google Patents

Methylcobalamine

Info

Publication number
IE41823L
IE41823L IE741654A IE165474A IE41823L IE 41823 L IE41823 L IE 41823L IE 741654 A IE741654 A IE 741654A IE 165474 A IE165474 A IE 165474A IE 41823 L IE41823 L IE 41823L
Authority
IE
Ireland
Prior art keywords
methylcobalamine
cyanocobalamine
aug
mono
added
Prior art date
Application number
IE741654A
Other versions
IE41823B1 (en
Original Assignee
L Opo Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7328998A external-priority patent/FR2240232A1/en
Priority claimed from FR7346829A external-priority patent/FR2256174A2/en
Application filed by L Opo Chemie filed Critical L Opo Chemie
Publication of IE41823L publication Critical patent/IE41823L/en
Publication of IE41823B1 publication Critical patent/IE41823B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Abstract

1419933 Methylcobalamine L'OPOCHIMIE 1 Aug 1974 [8 Aug 1973] 34008/74 Addition to 1355899 Heading C2V Methylcobalamine is prepared by the simultaneous reduction and methylation of cyanocobalamine in an aqueous methanolic solution containing at least 40 grams of cyanocobalamine per litre, through the action of mono-methyl oxalate and a metal powder. A cobalt salt may be added to the reaction mixture. In examples cyanocobalamine dissolved in aqueous methanol is converted to methylcobalamine by reaction with mono-methyl oxalate and zinc powder, cobalt chloride also being added to the reaction mixture. [GB1419933A]
IE1654/74A 1973-08-08 1974-08-06 Preparation of methylcobalamine IE41823B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7328998A FR2240232A1 (en) 1973-08-08 1973-08-08 Methylcobalamine prepn from cyanocobalamine - by reduction and methylation using methyl acid oxalate and a metal
FR7346829A FR2256174A2 (en) 1973-12-28 1973-12-28 Methylcobalamine prepn from cyanocobalamine - by reduction and methylation using methyl acid oxalate and a metal

Publications (2)

Publication Number Publication Date
IE41823L true IE41823L (en) 1975-02-08
IE41823B1 IE41823B1 (en) 1980-04-09

Family

ID=26217885

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1654/74A IE41823B1 (en) 1973-08-08 1974-08-06 Preparation of methylcobalamine

Country Status (16)

Country Link
JP (1) JPS5727119B2 (en)
AR (1) AR199756A1 (en)
CA (1) CA1019726A (en)
CH (1) CH583744A5 (en)
DE (1) DE2434967A1 (en)
DK (1) DK136775B (en)
ES (1) ES428798A1 (en)
GB (1) GB1419933A (en)
IE (1) IE41823B1 (en)
IL (1) IL45384A (en)
IN (1) IN139935B (en)
LU (1) LU70582A1 (en)
NL (1) NL7410061A (en)
NO (1) NO742545L (en)
OA (1) OA04753A (en)
SE (1) SE412589B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1394174B1 (en) 2001-06-05 2015-11-11 Eisai R&D Management Co., Ltd. Process for producing methylcobalamin
CN102391340A (en) * 2011-10-31 2012-03-28 河北玉星生物工程有限公司 Preparation method of mecobalamin
WO2018007035A1 (en) * 2016-07-08 2018-01-11 Interquim, S.A. Process for the purification of methylcobalamin
CN114874276A (en) * 2022-04-21 2022-08-09 南京工业大学 Improved method for synthesizing mecobalamin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789252A (en) * 1971-11-10 1973-03-26 Boige Jean METHOD FOR MANUFACTURING METHYLCOBALAMINE

Also Published As

Publication number Publication date
CA1019726A (en) 1977-10-25
SE412589B (en) 1980-03-10
JPS5727119B2 (en) 1982-06-08
DE2434967A1 (en) 1975-02-20
NL7410061A (en) 1975-02-11
DK136775B (en) 1977-11-21
OA04753A (en) 1980-08-31
IE41823B1 (en) 1980-04-09
ES428798A1 (en) 1976-09-16
CH583744A5 (en) 1977-01-14
AR199756A1 (en) 1974-09-23
IL45384A0 (en) 1974-11-29
IN139935B (en) 1976-08-21
DK386274A (en) 1975-04-01
DK136775C (en) 1978-05-08
IL45384A (en) 1976-09-30
NO742545L (en) 1975-03-10
JPS5041900A (en) 1975-04-16
LU70582A1 (en) 1976-05-31
AU7188674A (en) 1976-02-05
SE7410005L (en) 1975-02-10
GB1419933A (en) 1975-12-31

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