IE41222B1 - New 1-aryl-uracils their production and their medicinal use - Google Patents

New 1-aryl-uracils their production and their medicinal use

Info

Publication number
IE41222B1
IE41222B1 IE660/75A IE66075A IE41222B1 IE 41222 B1 IE41222 B1 IE 41222B1 IE 660/75 A IE660/75 A IE 660/75A IE 66075 A IE66075 A IE 66075A IE 41222 B1 IE41222 B1 IE 41222B1
Authority
IE
Ireland
Prior art keywords
compounds
alkyl
represent hydrogen
different
aryl
Prior art date
Application number
IE660/75A
Other versions
IE41222L (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE41222L publication Critical patent/IE41222L/en
Publication of IE41222B1 publication Critical patent/IE41222B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)

Abstract

1456964 1-Aryl-uracils BAYER AG 25 March 1975 [26 March 1974 3 May 1974 30 Nov 1974] 12411/75 Heading C2C The invention comprises novel compounds (I) wherein Ar represents optionally substituted aryl, R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> can be identical or different and represent hydrogen, alkyl, halogen, alkoxy, nitro, acylamino, nitrile, alkoxycarbonyl, trifluoromethyl or the radicals wherein R<SP>8</SP> and B<SP>9</SP> can be identical or different and represent hydrogen, alkyl or alkenyl, or wherein R<SP>8</SP> and R<SP>9</SP> together with the nitrogen atom can form a heterocyclic ring which optionally contains further hetero-atoms and, R<SP>5</SP>, R<SP>6</SP> and R<SP>7</SP> can be identical or different and represent hydrogen, alkyl, alkenyl or cyano and X represents oxygen, sulphur, SO or SO 2 or a salt thereof. They are made by reacting compounds (II) (obtained from the corresponding nitro compounds) with (R<SP>10</SP> is alkyl) and cyclizing the compounds (IV) obtained, or by reacting (II) with (R<SP>11</SP> and R<SP>12</SP> are alkyl) and heating the compounds (VII) obtained to give the nitriles (VIII) which are hydrolysed to give (I) via compounds (IX). Pharmaceutical preparations active against coccidiosis contain (I) as active ingredient. Administration may be orally, parenterally or topically. [GB1456964A]
IE660/75A 1974-03-26 1975-03-25 New 1-aryl-uracils their production and their medicinal use IE41222B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2414612A DE2414612A1 (en) 1974-03-26 1974-03-26 1-ARYLURACILE, THE METHOD FOR MANUFACTURING IT AND ITS USE AS A MEDICINAL PRODUCT

Publications (2)

Publication Number Publication Date
IE41222L IE41222L (en) 1975-09-26
IE41222B1 true IE41222B1 (en) 1979-11-21

Family

ID=5911235

Family Applications (1)

Application Number Title Priority Date Filing Date
IE660/75A IE41222B1 (en) 1974-03-26 1975-03-25 New 1-aryl-uracils their production and their medicinal use

Country Status (20)

Country Link
JP (2) JPS50129720A (en)
AT (1) AT336039B (en)
BE (1) BE827119A (en)
CA (1) CA1036604A (en)
CS (1) CS188945B2 (en)
DD (1) DD119232A5 (en)
DE (1) DE2414612A1 (en)
DK (1) DK139138C (en)
ES (1) ES436034A1 (en)
FI (1) FI750870A (en)
FR (1) FR2265388B1 (en)
GB (1) GB1456964A (en)
HU (1) HU170782B (en)
IE (1) IE41222B1 (en)
IL (1) IL46890A0 (en)
LU (1) LU72124A1 (en)
NL (1) NL7503630A (en)
PH (1) PH12431A (en)
SE (1) SE7503470L (en)
ZA (1) ZA751883B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10040174A1 (en) 2000-08-17 2002-02-28 Bayer Ag Treatment of coccidiosis comprises administration of haloalkylsulfonyl substituted phenoxyphenyl-triazinetrione derivatives
WO2018157843A1 (en) * 2017-03-02 2018-09-07 中国科学院上海药物研究所 2-(substituted benzene matrix) aromatic formate fto inhibitor, preparation method therefor, and applications thereof
CN113166076A (en) * 2018-11-30 2021-07-23 大塚制药株式会社 Heterocyclic compounds for the treatment of epilepsy

Also Published As

Publication number Publication date
GB1456964A (en) 1976-12-01
DD119232A5 (en) 1976-04-12
ATA223675A (en) 1976-08-15
ES436034A1 (en) 1977-01-01
JPS50140467A (en) 1975-11-11
DK128175A (en) 1975-09-27
CS188945B2 (en) 1979-03-30
BE827119A (en) 1975-09-25
FR2265388B1 (en) 1978-08-04
SE7503470L (en) 1975-09-29
DK139138C (en) 1979-05-28
HU170782B (en) 1977-09-28
AU7952075A (en) 1976-09-30
CA1036604A (en) 1978-08-15
DE2414612A1 (en) 1975-10-16
AT336039B (en) 1977-04-12
ZA751883B (en) 1976-02-25
FR2265388A1 (en) 1975-10-24
DK139138B (en) 1978-12-27
PH12431A (en) 1979-02-22
IL46890A0 (en) 1975-05-22
FI750870A (en) 1975-09-27
JPS50129720A (en) 1975-10-14
NL7503630A (en) 1975-09-30
LU72124A1 (en) 1976-02-04
IE41222L (en) 1975-09-26

Similar Documents

Publication Publication Date Title
ES8607966A1 (en) Dihydropyridine derivatives, their production and use.
FI892787A0 (en) Analogous Process for Preparing Therapeutically Useful 1-Indolylalkyl-4- (Substituted Pyridinyl) Piperazines
GB1490306A (en) 3-amino-indazolecarboxylic acid derivatives process for their preparation and their use as medicaments
ES384015A1 (en) Heterocyclic-substituted n-imidazol plant-growth influencing agents
ES430119A1 (en) 2-(Phenyl-amino-2-imidazolines and salts thereof
GB1155937A (en) Novel Oxazolidinones
GB1397501A (en) Thienopyrimidine derivatives processes for producing them and compositions containing them
GB1429141A (en) 1-substituted pyrazol-5-ones their production and their medicinal use
IE41222B1 (en) New 1-aryl-uracils their production and their medicinal use
IE36127L (en) 3-benzylpyridines
GB1490507A (en) Piperazine derivatives
GB1454864A (en) Thioureas
GB1450801A (en) Pyridinecarboxamide sulphonylurea hypoglycemic agents
GB1462521A (en) Triazole derivatives
GB1324579A (en) N-substituted 3-aminoalkoxy-6-hydrazinopyridazines having antihypertensive activity and their preparation
GB1297401A (en)
GB1463582A (en) Pyridine derivatives
GB1423430A (en) Thioamides
GB1363203A (en) Thiophosphoric acid ester amides and their use as pesticides
GB1490406A (en) Oxadiazoles
IE40182L (en) Aminoethanol derivatives
GB1135947A (en) Novel biologically active derivatives of phenanthridone
SE7501871L (en)
GB1316674A (en) 1-disubstituted-amino pyrazoles and the production thereof
GB1382974A (en) Process for the production of thiosemicarbazides