IE41040L - Complexes of biologically active substances with an¹insoluble carrier - Google Patents
Complexes of biologically active substances with an¹insoluble carrierInfo
- Publication number
- IE41040L IE41040L IE750996A IE99675A IE41040L IE 41040 L IE41040 L IE 41040L IE 750996 A IE750996 A IE 750996A IE 99675 A IE99675 A IE 99675A IE 41040 L IE41040 L IE 41040L
- Authority
- IE
- Ireland
- Prior art keywords
- biologically active
- poly
- active substances
- complexes
- carrier
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Polyesters Or Polycarbonates (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The biologically active substance is bound covalently to poly(hydroxymethylene) or poly(vinylenecarbonate) either directly or after reaction with a coupling component. The coupling component, which is optionally employed, is bound to the poly(hydroxymethylene) and the biologically active compound by a covalent bond in each case. When poly(vinylenecarbonate) is used, the remaining carbonate groups are hydrolysed. The biologically active substances which are obtained are suitable for use in affinity chromatography.
[GB1512651A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742421789 DE2421789C3 (en) | 1974-05-06 | Biologically active products and processes for their manufacture |
Publications (2)
Publication Number | Publication Date |
---|---|
IE41040L true IE41040L (en) | 1975-11-06 |
IE41040B1 IE41040B1 (en) | 1979-10-10 |
Family
ID=5914739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE996/75A IE41040B1 (en) | 1974-05-06 | 1975-05-05 | Biologically active compounds and process for their manufacture |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS599153B2 (en) |
AT (1) | AT338417B (en) |
BE (1) | BE828776A (en) |
CA (1) | CA1063049A (en) |
CH (1) | CH630410A5 (en) |
DK (1) | DK196175A (en) |
ES (1) | ES437153A1 (en) |
FI (1) | FI60216C (en) |
FR (1) | FR2270266B1 (en) |
GB (1) | GB1512651A (en) |
IE (1) | IE41040B1 (en) |
IT (1) | IT1054620B (en) |
LU (1) | LU72407A1 (en) |
NL (1) | NL181782C (en) |
NO (1) | NO144672C (en) |
SE (2) | SE427086B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2552510C3 (en) * | 1975-11-22 | 1981-02-19 | Behringwerke Ag, 3550 Marburg | Biologically active compounds and processes for their preparation |
WO2003070823A2 (en) * | 2002-02-20 | 2003-08-28 | The General Hospital Corporation | Conjugates comprising a biodegradable polymer and uses therefor |
JP6476934B2 (en) * | 2015-02-02 | 2019-03-06 | 東ソー株式会社 | Novel polymer and cell culture substrate having the same |
-
1975
- 1975-04-29 ES ES437153A patent/ES437153A1/en not_active Expired
- 1975-04-30 FI FI751299A patent/FI60216C/en not_active IP Right Cessation
- 1975-05-01 NL NLAANVRAGE7505152,A patent/NL181782C/en not_active IP Right Cessation
- 1975-05-02 CA CA226,193A patent/CA1063049A/en not_active Expired
- 1975-05-02 IT IT22967/75A patent/IT1054620B/en active
- 1975-05-05 GB GB18761/75A patent/GB1512651A/en not_active Expired
- 1975-05-05 AT AT342275A patent/AT338417B/en not_active IP Right Cessation
- 1975-05-05 NO NO751599A patent/NO144672C/en unknown
- 1975-05-05 CH CH575075A patent/CH630410A5/en not_active IP Right Cessation
- 1975-05-05 LU LU72407A patent/LU72407A1/xx unknown
- 1975-05-05 IE IE996/75A patent/IE41040B1/en unknown
- 1975-05-05 DK DK196175A patent/DK196175A/en not_active Application Discontinuation
- 1975-05-06 SE SE7505275A patent/SE427086B/en not_active IP Right Cessation
- 1975-05-06 BE BE156099A patent/BE828776A/en not_active IP Right Cessation
- 1975-05-06 JP JP50054436A patent/JPS599153B2/en not_active Expired
- 1975-05-06 FR FR7514177A patent/FR2270266B1/fr not_active Expired
-
1978
- 1978-05-16 SE SE7805544A patent/SE444947B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES437153A1 (en) | 1977-04-16 |
NL181782B (en) | 1987-06-01 |
FI60216B (en) | 1981-08-31 |
NL181782C (en) | 1987-11-02 |
SE7505275L (en) | 1975-11-07 |
GB1512651A (en) | 1978-06-01 |
ATA342275A (en) | 1976-12-15 |
FI751299A (en) | 1975-11-07 |
IE41040B1 (en) | 1979-10-10 |
NO751599L (en) | 1975-11-07 |
DK196175A (en) | 1975-11-07 |
NO144672C (en) | 1981-10-14 |
NO144672B (en) | 1981-07-06 |
DE2421789A1 (en) | 1975-11-13 |
CA1063049A (en) | 1979-09-25 |
AU8081875A (en) | 1976-11-11 |
SE427086B (en) | 1983-03-07 |
FR2270266B1 (en) | 1979-03-16 |
SE444947B (en) | 1986-05-20 |
BE828776A (en) | 1975-11-06 |
LU72407A1 (en) | 1977-02-09 |
FR2270266A1 (en) | 1975-12-05 |
IT1054620B (en) | 1981-11-30 |
DE2421789B2 (en) | 1976-10-07 |
JPS50155679A (en) | 1975-12-16 |
JPS599153B2 (en) | 1984-02-29 |
FI60216C (en) | 1981-12-10 |
CH630410A5 (en) | 1982-06-15 |
NL7505152A (en) | 1975-11-10 |
AT338417B (en) | 1977-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU502784B2 (en) | Immobilized biologically active substances | |
IE41328B1 (en) | 16-hydroxy prostanoic acid derivatives | |
JPS52104591A (en) | Carrier for organic compounds* process for preparing the same* biological reagent and catalyst containing the same | |
NL7413440A (en) | PROCEDURE FOR THE PREPARATION OF RECONSTRUCTED BUCKET WITH LOW NITRATE CONTENT. | |
AU502914B2 (en) | Immobilized antibodies, antigens, or antisera | |
CA1035810A (en) | Concentric brake booster with accumulator | |
ES453362A1 (en) | Carrier-bound biologically active substances and process for their manufacture | |
AU497803B2 (en) | Araliphatic nitrogen compounds | |
FR2433544B1 (en) | ||
CA1035709A (en) | Gleiter (sled) | |
IE41898L (en) | Decahydroisoquinolines | |
IE41040L (en) | Complexes of biologically active substances with an¹insoluble carrier | |
CA1018072A (en) | Utility vehicle | |
AU462701B2 (en) | Polymer biologically active protein complexes | |
AU1378976A (en) | Dimerisation catalyst | |
IE40296L (en) | Quinoline-and pyridine-carbamates | |
EP0172580A3 (en) | Modified polypeptide supports | |
IE37690B1 (en) | Compositions containing compounds of the eburnane structure | |
AU515037B2 (en) | Polymer bound catalyst containing manganese | |
CA1012888A (en) | Method of preparation of the dry hydrophilic polymeric carrier of biologically active compounds activated by cyanogen bromide | |
CA1035070A (en) | Adhesive composition | |
GB1523747A (en) | Process for producing methacrolein | |
CA1029747A (en) | Purification of n, n'-di-2-naphtyl-p-phenylenediamine using a mixed solvent system | |
JPS5291898A (en) | Water-insoluble tannin preparation | |
CA1028617A (en) | Iodophor formulation |