ES453362A1 - Carrier-bound biologically active substances and process for their manufacture - Google Patents

Carrier-bound biologically active substances and process for their manufacture

Info

Publication number
ES453362A1
ES453362A1 ES453362A ES453362A ES453362A1 ES 453362 A1 ES453362 A1 ES 453362A1 ES 453362 A ES453362 A ES 453362A ES 453362 A ES453362 A ES 453362A ES 453362 A1 ES453362 A1 ES 453362A1
Authority
ES
Spain
Prior art keywords
biologically active
manufacture
carrier
active substances
bound biologically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES453362A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of ES453362A1 publication Critical patent/ES453362A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/091—Phenol resins; Amino resins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/50—Chemical modification of a polymer wherein the polymer is a copolymer and the modification is taking place only on one or more of the monomers present in minority

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A compound made from a copolymer of vinylene glycol and a biologically active substance chemically bonded thereto is prepared by reacting a copolymer of vinylene carbonate with a biologically active substance. The cyclocarbonate groups are converted into hydroxyl groups before or after the reaction. The novel compounds are used for affinity chromatography, for carrying out immune reactions or for carrying out enzyme reactions.
ES453362A 1975-11-22 1976-11-16 Carrier-bound biologically active substances and process for their manufacture Expired ES453362A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2552510A DE2552510C3 (en) 1975-11-22 1975-11-22 Biologically active compounds and processes for their preparation

Publications (1)

Publication Number Publication Date
ES453362A1 true ES453362A1 (en) 1977-11-16

Family

ID=5962419

Family Applications (1)

Application Number Title Priority Date Filing Date
ES453362A Expired ES453362A1 (en) 1975-11-22 1976-11-16 Carrier-bound biologically active substances and process for their manufacture

Country Status (20)

Country Link
JP (1) JPS6048524B2 (en)
AT (1) AT358275B (en)
AU (1) AU513890B2 (en)
BE (1) BE848601A (en)
CA (1) CA1069070A (en)
CH (1) CH636628A5 (en)
DE (1) DE2552510C3 (en)
DK (1) DK522976A (en)
ES (1) ES453362A1 (en)
FI (1) FI763314A (en)
FR (1) FR2332287A1 (en)
GB (1) GB1571182A (en)
IL (1) IL50940A (en)
IT (1) IT1121742B (en)
LU (1) LU76243A1 (en)
NL (1) NL7612771A (en)
NO (1) NO763975L (en)
SE (1) SE430066B (en)
YU (1) YU283676A (en)
ZA (1) ZA766942B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210722A (en) * 1977-11-14 1980-07-01 Minnesota Mining And Manufacturing Company Protein immobilizer
DE2757206A1 (en) * 1977-12-22 1979-07-05 Basf Ag POLYAMIDACETAL
GB2043996B (en) * 1978-12-27 1983-09-07 Nihon Dempa Kogyo Co Thickness shear quartz crystal oscillator
FR2450263A1 (en) * 1979-02-28 1980-09-26 Dow Chemical Co Coupling protein to latex particles having epoxy gps. - for use in immunological analysis esp. pregnancy testing
EP0015473A1 (en) * 1979-02-28 1980-09-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for immobilizing cells
DE3145082A1 (en) * 1981-11-13 1983-05-19 Behringwerke Ag, 3550 Marburg "A LATEX, BIOLOGICALLY ACTIVE LATEX CONJUGATES AND METHOD FOR THEIR PRODUCTION"
JPS58209984A (en) * 1982-05-28 1983-12-07 Japan Synthetic Rubber Co Ltd Carrier composed of granular polymer
DE3243591A1 (en) * 1982-11-25 1984-05-30 Hoechst Ag, 6230 Frankfurt VINYLENE CARBONATE POLYMERYSATE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
DE3344912A1 (en) * 1983-12-13 1985-06-20 Hoechst Ag, 6230 Frankfurt CROSSLINKED POLYMERISATES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
SE8401437D0 (en) * 1984-03-14 1984-03-14 Sven Gothe SURFACE MODIFIED PLASTIC SURFACES AND ITS APPLICATIONS FOR IMMUNOASSAYS (IA)
DE3413904A1 (en) * 1984-04-13 1985-10-24 Hoechst Ag, 6230 Frankfurt POLYMERISATES BASED ON POLYVINYLENE CARBONATE AND / OR POLYHYDROXYMETHYLENE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
GB8423228D0 (en) * 1984-09-14 1984-10-17 Unilever Plc Specific binding materials
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
DE3637421C1 (en) * 1986-11-03 1987-10-29 Nerbe Plus Ges Fuer Medizinisc Reaction vessel for the blood coagulation reaction
DE3811042A1 (en) * 1988-03-31 1989-10-19 Merck Patent Gmbh ION EXCHANGER
DE19715504C2 (en) 1997-04-14 2000-10-26 Max Planck Gesellschaft PMMA membranes with polyethylene glycol-coupled active substances
JP2001247738A (en) * 2000-03-06 2001-09-11 Unitika Chem Co Ltd Polyvinyl alcohol-based resin composition and paper coating agent consisting essentially of the same
JP6405669B2 (en) * 2014-03-31 2018-10-17 東ソー株式会社 Novel polymer and cell culture substrate having the same
CN108264604B (en) * 2016-12-30 2020-08-11 北京爱普聚合科技有限公司 Dry fracturing fluid drag reduction thickener and preparation method thereof
EP3502274A1 (en) * 2017-12-22 2019-06-26 Attomol GmbH Sample carrier and method of production
CN110504452B (en) * 2019-09-04 2022-06-21 中国科学院青岛生物能源与过程研究所 High-peel-strength polymer binder and application thereof in secondary lithium battery

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE810605A (en) * 1973-03-01 1974-05-29 ENZYMES AND OTHER PROTEINS LINKED TO POLYMERIC SUBSTRATES CONTAINING VINYLENE CARBONATE UNITS
ES437153A1 (en) * 1974-05-06 1977-04-16 Marburgnlahn Biologically active compounds and process for their manufacture

Also Published As

Publication number Publication date
ZA766942B (en) 1977-10-26
AU1981776A (en) 1978-05-25
BE848601A (en) 1977-05-23
ATA863176A (en) 1980-01-15
GB1571182A (en) 1980-07-09
AT358275B (en) 1980-08-25
DK522976A (en) 1977-05-23
NL7612771A (en) 1977-05-24
YU283676A (en) 1982-06-30
FI763314A (en) 1977-05-23
IL50940A0 (en) 1977-01-31
DE2552510B2 (en) 1980-06-04
FR2332287B1 (en) 1982-11-12
CA1069070A (en) 1980-01-01
FR2332287A1 (en) 1977-06-17
LU76243A1 (en) 1977-06-07
AU513890B2 (en) 1981-01-15
JPS5265596A (en) 1977-05-31
CH636628A5 (en) 1983-06-15
SE7612998L (en) 1977-05-23
IT1121742B (en) 1986-04-23
IL50940A (en) 1980-03-31
DE2552510C3 (en) 1981-02-19
DE2552510A1 (en) 1977-06-30
NO763975L (en) 1977-05-24
JPS6048524B2 (en) 1985-10-28
SE430066B (en) 1983-10-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103