IE40745B1 - Cephem derivatives and preparation thereof - Google Patents
Cephem derivatives and preparation thereofInfo
- Publication number
- IE40745B1 IE40745B1 IE2113/74A IE211374A IE40745B1 IE 40745 B1 IE40745 B1 IE 40745B1 IE 2113/74 A IE2113/74 A IE 2113/74A IE 211374 A IE211374 A IE 211374A IE 40745 B1 IE40745 B1 IE 40745B1
- Authority
- IE
- Ireland
- Prior art keywords
- substituted
- methyl
- formula
- tetrazolyl
- phenyl
- Prior art date
Links
- 150000001782 cephems Chemical class 0.000 title abstract 2
- -1 2 - methyl - 1,3,4 - thiadiazolyl Chemical group 0.000 abstract 15
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- RDOXTESZEPMUJZ-UHFFFAOYSA-N anisole Chemical compound COC1=CC=CC=C1 RDOXTESZEPMUJZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000002541 furyl group Chemical group 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002883 imidazolyl group Chemical group 0.000 abstract 2
- 125000001786 isothiazolyl group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 2
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 2
- 125000000335 thiazolyl group Chemical group 0.000 abstract 2
- 125000001425 triazolyl group Chemical group 0.000 abstract 2
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000006710 (C2-C12) alkenyl group Chemical group 0.000 abstract 1
- 125000000081 (C5-C8) cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000002188 cycloheptatrienyl group Chemical group C1(=CC=CC=CC1)* 0.000 abstract 1
- JSYGRUBHOCKMGQ-UHFFFAOYSA-N dichloramine Chemical compound ClNCl JSYGRUBHOCKMGQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000006052 feed supplement Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- UZKWTJUDCOPSNM-UHFFFAOYSA-N methoxybenzene Substances CCCCOC=C UZKWTJUDCOPSNM-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000005633 phthalidyl group Chemical group 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000005030 pyridylthio group Chemical group N1=C(C=CC=C1)S* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE2180/77A IE40747B1 (en) | 1973-10-17 | 1974-10-14 | Cephem derivatives and preparation thereof |
| IE2179/77A IE40746B1 (en) | 1973-10-17 | 1974-10-14 | Cephem derivatives and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40709773A | 1973-10-17 | 1973-10-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40745L IE40745L (en) | 1975-04-17 |
| IE40745B1 true IE40745B1 (en) | 1979-08-15 |
Family
ID=23610572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2113/74A IE40745B1 (en) | 1973-10-17 | 1974-10-14 | Cephem derivatives and preparation thereof |
Country Status (22)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2833121A1 (en) * | 2011-04-28 | 2012-11-01 | Shionogi & Co., Ltd. | Novel cephem compound having catechol or pseudo-catechol structure |
| WO2013002215A1 (ja) * | 2011-06-27 | 2013-01-03 | 塩野義製薬株式会社 | ピリジニウム基を有するセフェム化合物 |
-
1974
- 1974-10-07 SE SE7412602A patent/SE429342B/xx unknown
- 1974-10-11 NO NO743667A patent/NO743667L/no unknown
- 1974-10-14 GB GB22873/76A patent/GB1481810A/en not_active Expired
- 1974-10-14 GB GB22871/76A patent/GB1481808A/en not_active Expired
- 1974-10-14 IL IL45849A patent/IL45849A0/xx unknown
- 1974-10-14 IE IE2113/74A patent/IE40745B1/xx unknown
- 1974-10-14 GB GB22872/76A patent/GB1481809A/en not_active Expired
- 1974-10-14 GB GB44350/74A patent/GB1481807A/en not_active Expired
- 1974-10-15 ZA ZA00746544A patent/ZA746544B/xx unknown
- 1974-10-15 MW MW40/74A patent/MW4074A1/xx unknown
- 1974-10-15 MW MW41/74A patent/MW4174A1/xx unknown
- 1974-10-16 DK DK542174A patent/DK542174A/da not_active Application Discontinuation
- 1974-10-16 CA CA211,504A patent/CA1064019A/en not_active Expired
- 1974-10-16 ES ES431069A patent/ES431069A1/es not_active Expired
- 1974-10-16 AR AR256116A patent/AR209283A1/es active
- 1974-10-16 DD DD181737A patent/DD114266A5/xx unknown
- 1974-10-16 DE DE19742449834 patent/DE2449834A1/de not_active Ceased
- 1974-10-17 NL NL7413643A patent/NL7413643A/xx not_active Application Discontinuation
- 1974-10-17 FR FR7435015A patent/FR2257298B1/fr not_active Expired
- 1974-10-17 BE BE1006235A patent/BE821164A/xx unknown
- 1974-10-17 LU LU71128A patent/LU71128A1/xx unknown
- 1974-10-17 JP JP49118743A patent/JPS50121293A/ja active Pending
- 1974-10-17 PL PL1974174893A patent/PL95747B1/pl unknown
- 1974-10-18 OA OA55326A patent/OA04935A/xx unknown
- 1974-11-04 ZM ZM161/74A patent/ZM16174A1/xx unknown
-
1975
- 1975-08-18 AR AR260031A patent/AR213726A1/es active
-
1976
- 1976-08-02 ES ES450398A patent/ES450398A1/es not_active Expired
- 1976-08-02 ES ES450397A patent/ES450397A1/es not_active Expired
- 1976-08-02 ES ES450399A patent/ES450399A1/es not_active Expired
-
1977
- 1977-09-23 SE SE7710697A patent/SE7710697L/xx not_active Application Discontinuation
-
1978
- 1978-06-28 SU SU782377452A patent/SU974936A3/ru active
-
1982
- 1982-01-20 JP JP57007361A patent/JPS5822480B2/ja not_active Expired
-
1983
- 1983-01-17 JP JP58005766A patent/JPS58131988A/ja active Pending
Also Published As
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