IE40624L - Phenylpropanolamines - Google Patents
PhenylpropanolaminesInfo
- Publication number
- IE40624L IE40624L IE742101A IE210174A IE40624L IE 40624 L IE40624 L IE 40624L IE 742101 A IE742101 A IE 742101A IE 210174 A IE210174 A IE 210174A IE 40624 L IE40624 L IE 40624L
- Authority
- IE
- Ireland
- Prior art keywords
- protecting group
- reducing
- alkoxy
- formula
- oct
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/08—Amines; Quaternary ammonium compounds containing oxygen or sulfur
- A01N33/10—Amines; Quaternary ammonium compounds containing oxygen or sulfur having at least one oxygen or sulfur atom directly attached to an aromatic ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1475913 Phenylpropanolamines BOEHRINGER INGELHEIM GmbH 9 Oct 1974 [11 Oct 1973] 43792/74 Heading C2C Compounds of the general formula (R 1 = H, halogen, CF 3 , OH, C 1-4 alkyl or alkoxy; R 2 = H, C 1-4 alkyl, benzyl) and their salts are prepared by (a) reducing a compound of the formula (R 2 <SP>1</SP> = R 2 , C 1-4 alkanoyl, benzoyl; R 3 =alkoxy, substituted alkoxy) with a complex hydride and, if necessary, deacylating the product, (b) removing the protecting group(s) in a compound of the formula (R 4 = H, protecting group; R 5 = R 1 , OR 7 ; R 6 = R 2 , protecting group; R 7 = protecting group; at least one of M 4,6,7 =protecting group), (c) reducing the corresponding nitropropanol, (d) alkylating or benzylating the primary amine or (e) reducing the corresponding amide, optionally followed by resolution and/or salt formation. The above compounds are sympathicomimetics and increase blood pressure; they may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
[GB1475913A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732351027 DE2351027A1 (en) | 1973-10-11 | 1973-10-11 | PROPANOL DERIVATIVES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40624L true IE40624L (en) | 1975-04-11 |
| IE40624B1 IE40624B1 (en) | 1979-07-18 |
Family
ID=5895110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2101/74A IE40624B1 (en) | 1973-10-11 | 1974-10-10 | Phenylpropanolamines |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS5064236A (en) |
| AT (1) | AT343627B (en) |
| BE (1) | BE820938A (en) |
| BG (2) | BG24797A3 (en) |
| CA (1) | CA1041546A (en) |
| CS (2) | CS176284B2 (en) |
| DD (1) | DD115900A5 (en) |
| DE (1) | DE2351027A1 (en) |
| DK (1) | DK138848C (en) |
| ES (4) | ES430420A1 (en) |
| FI (1) | FI282074A (en) |
| FR (1) | FR2247221B1 (en) |
| GB (1) | GB1475913A (en) |
| HU (1) | HU167904B (en) |
| IE (1) | IE40624B1 (en) |
| IL (1) | IL45813A (en) |
| NL (1) | NL7413317A (en) |
| NO (1) | NO139384C (en) |
| PH (1) | PH12476A (en) |
| PL (2) | PL93938B1 (en) |
| RO (2) | RO70259A (en) |
| SE (1) | SE7412790L (en) |
| SU (2) | SU560528A3 (en) |
| ZA (1) | ZA746424B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4071552A (en) | 1976-05-19 | 1978-01-31 | Ayerst Mckenna And Harrison Ltd. | Aryloxy aminobutanols, their preparation and use thereof |
| US4170653A (en) | 1976-05-19 | 1979-10-09 | Ayerst McKenna and Harrison Limited | Antidepressant naphthyloxy piperidino and pyrrolidino propanol ethers |
| ATE386525T1 (en) | 2001-08-27 | 2008-03-15 | Arpida Ag | 3-SUBSTITUTED 6,7-DIHYDROXYTETRAHYDROISOCINOLINE DERIVATIVES FOR USE AS ANTIBATERAL AGENTS |
-
1973
- 1973-10-11 DE DE19732351027 patent/DE2351027A1/en active Pending
-
1974
- 1974-09-20 AT AT756274A patent/AT343627B/en not_active IP Right Cessation
- 1974-09-26 ES ES430420A patent/ES430420A1/en not_active Expired
- 1974-09-26 FI FI2820/74A patent/FI282074A/fi unknown
- 1974-09-27 CS CS6670A patent/CS176284B2/cs unknown
- 1974-09-27 CS CS7031A patent/CS176293B2/cs unknown
- 1974-10-03 RO RO7482882A patent/RO70259A/en unknown
- 1974-10-07 SU SU2064398A patent/SU560528A3/en active
- 1974-10-08 RO RO7480152A patent/RO68469A/en unknown
- 1974-10-09 JP JP49115688A patent/JPS5064236A/ja active Pending
- 1974-10-09 BG BG7400033086A patent/BG24797A3/en unknown
- 1974-10-09 GB GB4379274A patent/GB1475913A/en not_active Expired
- 1974-10-09 ZA ZA00746424A patent/ZA746424B/en unknown
- 1974-10-09 DD DD181592A patent/DD115900A5/xx unknown
- 1974-10-09 BG BG7400027898A patent/BG24796A3/en unknown
- 1974-10-09 HU HUBO1520A patent/HU167904B/hu unknown
- 1974-10-09 IL IL45813A patent/IL45813A/en unknown
- 1974-10-10 CA CA211,135A patent/CA1041546A/en not_active Expired
- 1974-10-10 NL NL7413317A patent/NL7413317A/en not_active Application Discontinuation
- 1974-10-10 PH PH16396A patent/PH12476A/en unknown
- 1974-10-10 NO NO743653A patent/NO139384C/en unknown
- 1974-10-10 DK DK529874A patent/DK138848C/en active
- 1974-10-10 PL PL1974174735A patent/PL93938B1/pl unknown
- 1974-10-10 BE BE149420A patent/BE820938A/en unknown
- 1974-10-10 PL PL1974183237A patent/PL93903B1/pl unknown
- 1974-10-10 SE SE7412790A patent/SE7412790L/xx unknown
- 1974-10-10 IE IE2101/74A patent/IE40624B1/en unknown
- 1974-10-11 FR FR7434294A patent/FR2247221B1/fr not_active Expired
-
1975
- 1975-10-23 ES ES442022A patent/ES442022A1/en not_active Expired
- 1975-10-23 ES ES442023A patent/ES442023A1/en not_active Expired
- 1975-10-23 ES ES442024A patent/ES442024A1/en not_active Expired
- 1975-10-28 SU SU752184011A patent/SU586835A3/en active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1205957A (en) | Pharmaceutical compositions comprising 1-pnenoxy-2-aminopropanes | |
| IE780515L (en) | Morphine derivatives | |
| YU54189A (en) | Process for obtaining cephem derivatives and midproducts for the same | |
| GB1147379A (en) | 4-alkyl-dialkoxy-ª‡-methylphenethylamines and pharmacologically acceptable salts | |
| GB1481219A (en) | Preparation of benzodiazepines | |
| EG19361A (en) | A process for the preparation of piperidine compound having local anaesthetica and analgetic | |
| DE3688087T2 (en) | CEPHEMIC COMPOUNDS, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME. | |
| IE40624L (en) | Phenylpropanolamines | |
| IE780514L (en) | Morphine derivatives | |
| EP1074554A3 (en) | 7-acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | |
| GB1409648A (en) | Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof | |
| GB1443692A (en) | 1,2-diphenylethanolamine derivatives and their salts and the preparation thereof | |
| GB1462095A (en) | Substituted triazolo-1,5-benzodiazepines | |
| IE873212L (en) | Medicaments based on derivatives of 3,4-di-phenylpiperidine,¹the use of the derivatives as medicaments, and novel¹3,4-diphenylpiperidine derivatives and a process for the¹preparation therefor | |
| GB1235399A (en) | Polymethylene diamine derivatives | |
| IE39661L (en) | New aluminium and/or magnesium salts | |
| GB1449426A (en) | Phenoxyalkylamine derivatives and preparation therof | |
| GB1468079A (en) | Ethanolamine derivatives | |
| EP0295783A3 (en) | A derivative of codeine | |
| GB1391081A (en) | Optically active benzodiazepines | |
| GB1199126A (en) | 3-Amino-1,2,3,4-Tetrahydrofluorenes | |
| ES8400397A1 (en) | New peptide, process for preparation thereof and use thereof. | |
| ES8302719A1 (en) | New cephem compounds, processes for preparation thereof and pharmaceutical composition comprising the same. | |
| IE36035L (en) | Benzodiazepines. | |
| IE36262B1 (en) | Benzodiazepines |