IE40389B1 - 2,5-dideoxystreptamines and 6,7-diaza-2,4-dihydroxy-bicyclo -(3,2,1)-octanes and methods for their preparation - Google Patents
2,5-dideoxystreptamines and 6,7-diaza-2,4-dihydroxy-bicyclo -(3,2,1)-octanes and methods for their preparationInfo
- Publication number
- IE40389B1 IE40389B1 IE1640/74A IE164074A IE40389B1 IE 40389 B1 IE40389 B1 IE 40389B1 IE 1640/74 A IE1640/74 A IE 1640/74A IE 164074 A IE164074 A IE 164074A IE 40389 B1 IE40389 B1 IE 40389B1
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- dideoxystreptamines
- octanes
- diaza
- bicyclo
- Prior art date
Links
- JCMPBRIIKYXMFO-UHFFFAOYSA-N 6,7-diazabicyclo[3.2.1]octane-2,4-diol Chemical class OC1CC(O)C2NNC1C2 JCMPBRIIKYXMFO-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 101100234822 Caenorhabditis elegans ltd-1 gene Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 101150009274 nhr-1 gene Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/42—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitrogen-to-nitrogen bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1428938 2,5 - Dideoxy - streptamines SCHERICO Ltd 1 Aug 1974 [6 Aug 1973] 33966/74 Heading C2C Novel compounds (I) and (III) and their acid addition salts in which one of R 1 and R 2 is hydrogen and the other is hydrogen or C 1-4 alkyl, are prepared by reacting cis-4,8-dioxatricyclo-[5,1,O,O<SP>3,5</SP>]-octane with a hydrazine NHR 1 -NHR 2 to form a compound III or a racemate thereof which may be resolved (when one of R 1 and R 2 is C 1-4 alkyl) and, if desired hydrogenolysing a compound (III) and isolating the compound (I) formed as such, as a racemic mixture (when one of R 1 and R 2 is C 1-4 alkyl) or in the form of an acid addition salt.
[GB1428938A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38576473A | 1973-08-06 | 1973-08-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE40389L IE40389L (en) | 1975-02-06 |
IE40389B1 true IE40389B1 (en) | 1979-05-23 |
Family
ID=23522782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1640/74A IE40389B1 (en) | 1973-08-06 | 1974-08-01 | 2,5-dideoxystreptamines and 6,7-diaza-2,4-dihydroxy-bicyclo -(3,2,1)-octanes and methods for their preparation |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS5047947A (en) |
BE (1) | BE818430A (en) |
CH (1) | CH602570A5 (en) |
DE (1) | DE2437115A1 (en) |
FR (1) | FR2240017B1 (en) |
GB (1) | GB1428938A (en) |
IE (1) | IE40389B1 (en) |
IL (1) | IL45386A (en) |
IT (1) | IT1033086B (en) |
NL (1) | NL7410359A (en) |
SE (1) | SE7409947L (en) |
ZA (1) | ZA744937B (en) |
-
1974
- 1974-07-31 CH CH1060074A patent/CH602570A5/xx not_active IP Right Cessation
- 1974-08-01 IE IE1640/74A patent/IE40389B1/en unknown
- 1974-08-01 ZA ZA00744937A patent/ZA744937B/en unknown
- 1974-08-01 SE SE7409947A patent/SE7409947L/xx not_active Application Discontinuation
- 1974-08-01 FR FR7426817A patent/FR2240017B1/fr not_active Expired
- 1974-08-01 GB GB3396674A patent/GB1428938A/en not_active Expired
- 1974-08-01 DE DE2437115A patent/DE2437115A1/en not_active Withdrawn
- 1974-08-01 IT IT25837/74A patent/IT1033086B/en active
- 1974-08-01 NL NL7410359A patent/NL7410359A/en not_active Application Discontinuation
- 1974-08-02 JP JP49088163A patent/JPS5047947A/ja active Pending
- 1974-08-02 IL IL45386A patent/IL45386A/en unknown
- 1974-08-02 BE BE147233A patent/BE818430A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR2240017B1 (en) | 1977-06-03 |
IE40389L (en) | 1975-02-06 |
FR2240017A1 (en) | 1975-03-07 |
JPS5047947A (en) | 1975-04-28 |
CH602570A5 (en) | 1978-07-31 |
DE2437115A1 (en) | 1975-02-20 |
IT1033086B (en) | 1979-07-10 |
NL7410359A (en) | 1975-02-10 |
IL45386A (en) | 1978-10-31 |
AU7194174A (en) | 1976-02-05 |
ZA744937B (en) | 1975-08-27 |
IL45386A0 (en) | 1974-11-29 |
GB1428938A (en) | 1976-03-24 |
SE7409947L (en) | 1975-02-07 |
BE818430A (en) | 1975-02-03 |
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