IE39624B1 - Carbazole derivatives and anti-inflammatory preparations containing them - Google Patents
Carbazole derivatives and anti-inflammatory preparations containing themInfo
- Publication number
- IE39624B1 IE39624B1 IE1519/74A IE151974A IE39624B1 IE 39624 B1 IE39624 B1 IE 39624B1 IE 1519/74 A IE1519/74 A IE 1519/74A IE 151974 A IE151974 A IE 151974A IE 39624 B1 IE39624 B1 IE 39624B1
- Authority
- IE
- Ireland
- Prior art keywords
- carbazole derivatives
- preparations containing
- inflammatory preparations
- novel compounds
- inflammatory
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 125000000609 carbazolyl group Chemical class C1(=CC=CC=2C3=CC=CC=C3NC12)* 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- XKLNOVWDVMWTOB-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1h-carbazole Chemical class N1C2=CC=CC=C2C2=C1CCCC2 XKLNOVWDVMWTOB-UHFFFAOYSA-N 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2337154A DE2337154C2 (de) | 1973-07-18 | 1973-07-18 | Neue Carbazolderivate |
| DE2431292A DE2431292A1 (de) | 1974-06-27 | 1974-06-27 | Neue carbazol-derivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39624L IE39624L (en) | 1975-01-18 |
| IE39624B1 true IE39624B1 (en) | 1978-11-22 |
Family
ID=25765532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1519/74A IE39624B1 (en) | 1973-07-18 | 1974-07-18 | Carbazole derivatives and anti-inflammatory preparations containing them |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS5069072A (enExample) |
| AT (1) | AT342583B (enExample) |
| BG (1) | BG25793A3 (enExample) |
| CA (1) | CA1053682A (enExample) |
| CH (1) | CH619213A5 (enExample) |
| CS (1) | CS190431B2 (enExample) |
| DD (1) | DD114075A5 (enExample) |
| DK (1) | DK388074A (enExample) |
| ES (1) | ES428379A1 (enExample) |
| FI (1) | FI218874A7 (enExample) |
| FR (1) | FR2237628B1 (enExample) |
| GB (1) | GB1482771A (enExample) |
| HU (1) | HU173115B (enExample) |
| IE (1) | IE39624B1 (enExample) |
| IL (1) | IL45298A (enExample) |
| NL (1) | NL7409715A (enExample) |
| NO (1) | NO742601L (enExample) |
| RO (1) | RO72713A (enExample) |
| SE (1) | SE396602B (enExample) |
| SU (1) | SU511855A3 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005518375A (ja) * | 2001-12-14 | 2005-06-23 | ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｇタンパク質結合受容体（ｇｐｃｒ）のためのリガンドとしてのテトラヒドロカルバゾール誘導体 |
| WO2005026112A2 (en) * | 2003-09-12 | 2005-03-24 | Elixir Pharmaceuticals, Inc. | Methods of treating a disorder |
| US20060074124A1 (en) * | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| EP1817025A2 (en) | 2004-11-23 | 2007-08-15 | PTC Therapeutics, Inc. | Tetrahydrocarbazoles as active agents for inhibiting vegf production by translational control |
| AR088377A1 (es) | 2011-10-20 | 2014-05-28 | Siena Biotech Spa | Proceso para la preparacion de 6-cloro-2,3,4,9-tetrahidro-1h-carbazol-1-carboxamida y compuestos intermedios de esta |
| CN110753683B (zh) * | 2017-04-11 | 2024-02-09 | 吉斯诺治疗公司 | 咔唑化合物及其使用方法 |
| JP2021134141A (ja) * | 2020-02-21 | 2021-09-13 | エヌ・イーケムキャット株式会社 | 不均一系貴金属触媒を用いた芳香族化合物の製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7008628A (enExample) * | 1969-06-25 | 1970-12-29 |
-
1974
- 1974-07-15 BG BG027244A patent/BG25793A3/xx unknown
- 1974-07-16 DD DD179943A patent/DD114075A5/xx unknown
- 1974-07-17 ES ES428379A patent/ES428379A1/es not_active Expired
- 1974-07-17 FI FI2188/74A patent/FI218874A7/fi unknown
- 1974-07-17 HU HU24SC483A patent/HU173115B/hu unknown
- 1974-07-17 NO NO742601A patent/NO742601L/no unknown
- 1974-07-17 CS CS745109A patent/CS190431B2/cs unknown
- 1974-07-17 SE SE7409330A patent/SE396602B/xx unknown
- 1974-07-18 CA CA205,063A patent/CA1053682A/en not_active Expired
- 1974-07-18 FR FR7424991A patent/FR2237628B1/fr not_active Expired
- 1974-07-18 RO RO7479524A patent/RO72713A/ro unknown
- 1974-07-18 JP JP49082669A patent/JPS5069072A/ja active Pending
- 1974-07-18 DK DK388074A patent/DK388074A/da not_active Application Discontinuation
- 1974-07-18 CH CH990174A patent/CH619213A5/de not_active IP Right Cessation
- 1974-07-18 AT AT596074A patent/AT342583B/de active
- 1974-07-18 IE IE1519/74A patent/IE39624B1/xx unknown
- 1974-07-18 IL IL45298A patent/IL45298A/xx unknown
- 1974-07-18 SU SU2048652A patent/SU511855A3/ru active
- 1974-07-18 NL NL7409715A patent/NL7409715A/xx not_active Application Discontinuation
- 1974-07-18 GB GB31966/74A patent/GB1482771A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BG25793A3 (bg) | 1978-12-12 |
| IL45298A0 (en) | 1974-10-22 |
| RO72713A (ro) | 1982-09-09 |
| NL7409715A (nl) | 1975-01-21 |
| HU173115B (hu) | 1979-02-28 |
| SE396602B (sv) | 1977-09-26 |
| FR2237628A1 (enExample) | 1975-02-14 |
| JPS5069072A (enExample) | 1975-06-09 |
| FR2237628B1 (enExample) | 1977-05-20 |
| AT342583B (de) | 1978-04-10 |
| GB1482771A (en) | 1977-08-17 |
| FI218874A7 (enExample) | 1975-01-19 |
| IE39624L (en) | 1975-01-18 |
| IL45298A (en) | 1980-01-31 |
| ES428379A1 (es) | 1976-09-16 |
| NO742601L (enExample) | 1975-02-17 |
| SE7409330L (enExample) | 1975-01-20 |
| DD114075A5 (enExample) | 1975-07-12 |
| ATA596074A (de) | 1977-08-15 |
| DK388074A (enExample) | 1975-03-03 |
| SU511855A3 (ru) | 1976-04-25 |
| CS190431B2 (en) | 1979-05-31 |
| CA1053682A (en) | 1979-05-01 |
| CH619213A5 (en) | 1980-09-15 |
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